ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	160/932	423/7206	2.31777534348e-41
ko05033	Nicotine addiction	43/932	56/7206	9.49242956193e-28
ko04721	Synaptic vesicle cycle	52/932	80/7206	1.43898861346e-27
ko04724	Glutamatergic synapse	71/932	152/7206	6.94033462859e-25
ko05032	Morphine addiction	55/932	110/7206	2.80881951594e-21
ko04728	Dopaminergic synapse	72/932	185/7206	1.59531839637e-19
ko04713	Circadian entrainment	59/932	136/7206	6.98733252618e-19
ko04727	GABAergic synapse	51/932	110/7206	5.39479249032e-18
ko04725	Cholinergic synapse	62/932	160/7206	7.5884519953e-17
ko04723	Retrograde endocannabinoid signaling	65/932	175/7206	1.61951322558e-16
ko04726	Serotonergic synapse	52/932	137/7206	6.90043776799e-14
ko04024	cAMP signaling pathway	81/932	279/7206	4.08221388336e-13
ko04911	Insulin secretion	44/932	117/7206	8.76665585587e-12
ko04921	Oxytocin signaling pathway	63/932	209/7206	3.14712977745e-11
ko05031	Amphetamine addiction	36/932	91/7206	1.32171285556e-10
ko04020	Calcium signaling pathway	72/932	265/7206	2.62760933529e-10
ko04742	Taste transduction	27/932	61/7206	1.44284382251e-09
ko04720	Long-term potentiation	35/932	99/7206	8.17899741875e-09
ko04261	Adrenergic signaling in cardiomyocytes	57/932	205/7206	8.49323761822e-09
ko03040	Spliceosome	1/932	145/7206	5.74346767582e-08
ko04966	Collecting duct acid secretion	15/932	26/7206	8.20486139251e-08
ko04360	Axon guidance	59/932	233/7206	2.4083446488e-07
ko04970	Salivary secretion	31/932	95/7206	4.63766848629e-07
ko04744	Phototransduction	17/932	36/7206	5.30444760948e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	26/932	74/7206	7.8885311939e-07
ko04060	Cytokine-cytokine receptor interaction	5/932	191/7206	9.0300892534e-07
ko05203	Viral carcinogenesis	12/932	277/7206	1.52412459634e-06
ko04120	Ubiquitin mediated proteolysis	2/932	138/7206	2.07174156244e-06
ko05030	Cocaine addiction	25/932	73/7206	2.20843062818e-06
ko05168	Herpes simplex infection	5/932	182/7206	2.80396546362e-06
ko05110	Vibrio cholerae infection	22/932	63/7206	6.22421421648e-06
ko04514	Cell adhesion molecules (CAMs)	36/932	130/7206	7.42393197614e-06
ko04010	MAPK signaling pathway	70/932	321/7206	7.74004150085e-06
ko04740	Olfactory transduction	25/932	80/7206	1.40617621944e-05
ko03013	RNA transport	5/932	166/7206	1.74121527182e-05
ko04925	Aldosterone synthesis and secretion	30/932	105/7206	2.214070707e-05
ko04971	Gastric acid secretion	28/932	98/7206	4.668542876e-05
ko04730	Long-term depression	24/932	78/7206	4.68746667369e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/932	14/7206	0.000111047965044
ko04022	cGMP-PKG signaling pathway	48/932	216/7206	0.000119886295763
ko04745	Phototransduction - fly	14/932	38/7206	0.000158180960386
ko04540	Gap junction	32/932	128/7206	0.000162505277411
ko04924	Renin secretion	24/932	86/7206	0.000243338326424
ko05164	Influenza A	7/932	167/7206	0.000243847562294
ko04961	Endocrine and other factor-regulated calcium reabsorption	18/932	59/7206	0.000309011181686
ko05322	Systemic lupus erythematosus	6/932	151/7206	0.000314001017456
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/932	79/7206	0.000317120820445
ko05162	Measles	4/932	120/7206	0.000506406042433
ko03008	Ribosome biogenesis in eukaryotes	1/932	79/7206	0.000514499849893
ko04014	Ras signaling pathway	56/932	279/7206	0.000695253331793
ko04146	Peroxisome	2/932	89/7206	0.000698970190391
ko05120	Epithelial cell signaling in Helicobacter pylori infection	24/932	92/7206	0.000768479906948
ko04626	Plant-pathogen interaction	8/932	18/7206	0.00100283387181
ko04141	Protein processing in endoplasmic reticulum	10/932	184/7206	0.00113610926727
ko04621	NOD-like receptor signaling pathway	8/932	157/7206	0.00162399608247
ko04110	Cell cycle	7/932	145/7206	0.00163845642242
ko04260	Cardiac muscle contraction	24/932	98/7206	0.00199747174085
ko04972	Pancreatic secretion	26/932	111/7206	0.00235772994836
ko04750	Inflammatory mediator regulation of TRP channels	28/932	122/7206	0.00238193478713
ko04612	Antigen processing and presentation	2/932	77/7206	0.0031786983791
ko00561	Glycerolipid metabolism	1/932	63/7206	0.0036954421789
ko05205	Proteoglycans in cancer	20/932	271/7206	0.00409550711557
ko00310	Lysine degradation	2/932	73/7206	0.00458133607767
ko00240	Pyrimidine metabolism	5/932	110/7206	0.00590837394647
ko05169	Epstein-Barr virus infection	14/932	206/7206	0.00592498943861
ko04214	Apoptosis - fly	2/932	72/7206	0.00692849710047
ko04932	Non-alcoholic fatty liver disease (NAFLD)	12/932	182/7206	0.00710919256959
ko05166	HTLV-I infection	23/932	292/7206	0.00735259430374
ko00280	Valine, leucine and isoleucine degradation	1/932	54/7206	0.00771498398939
ko00480	Glutathione metabolism	1/932	55/7206	0.00772305651559
ko05161	Hepatitis B	11/932	173/7206	0.00787331590837
ko05321	Inflammatory bowel disease (IBD)	1/932	56/7206	0.00789613360833
ko04915	Estrogen signaling pathway	28/932	131/7206	0.00790498661383
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	6/932	15/7206	0.00816845915286
ko04064	NF-kappa B signaling pathway	4/932	96/7206	0.00826530810566
ko04371	Apelin signaling pathway	35/932	177/7206	0.0087972998166
ko05323	Rheumatoid arthritis	20/932	89/7206	0.0106238964619
ko00590	Arachidonic acid metabolism	1/932	52/7206	0.0114561302364
ko04145	Phagosome	32/932	162/7206	0.0124939451619
ko04640	Hematopoietic cell lineage	2/932	64/7206	0.0138394666474
ko05140	Leishmaniasis	3/932	75/7206	0.0149368674591
ko00260	Glycine, serine and threonine metabolism	1/932	48/7206	0.0168368743087
ko04630	Jak-STAT signaling pathway	8/932	132/7206	0.0174769250141
ko00330	Arginine and proline metabolism	2/932	61/7206	0.0199272697696
ko03018	RNA degradation	4/932	84/7206	0.0211367026376
ko05414	Dilated cardiomyopathy	23/932	112/7206	0.0221729475641
ko04015	Rap1 signaling pathway	49/932	278/7206	0.0222732491802
ko01200	Carbon metabolism	8/932	128/7206	0.0228389726898
ko03420	Nucleotide excision repair	1/932	46/7206	0.0251167546225
ko04391	Hippo signaling pathway - fly	19/932	90/7206	0.0261902182329
ko00983	Drug metabolism - other enzymes	1/932	42/7206	0.0365677086493
ko03022	Basal transcription factors	1/932	44/7206	0.038304261065
ko04916	Melanogenesis	27/932	142/7206	0.0419358291938
ko04071	Sphingolipid signaling pathway	30/932	162/7206	0.0429561201989
ko04964	Proximal tubule bicarbonate reclamation	8/932	29/7206	0.0447967687539
ko00564	Glycerophospholipid metabolism	6/932	99/7206	0.0479226492793
ko05034	Alcoholism	41/932	238/7206	0.0493005595313