ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	176/1175	423/7206	9.96188576145e-38
ko04724	Glutamatergic synapse	81/1175	152/7206	3.17531883317e-26
ko05033	Nicotine addiction	41/1175	56/7206	3.6844932272e-21
ko04713	Circadian entrainment	65/1175	136/7206	5.26267379633e-18
ko05032	Morphine addiction	56/1175	110/7206	2.93754584643e-17
ko04727	GABAergic synapse	55/1175	110/7206	1.60902568901e-16
ko04020	Calcium signaling pathway	96/1175	265/7206	1.27665998879e-15
ko04728	Dopaminergic synapse	75/1175	185/7206	1.34516938912e-15
ko04024	cAMP signaling pathway	98/1175	279/7206	4.5727558627e-15
ko04725	Cholinergic synapse	66/1175	160/7206	2.6776675451e-14
ko04723	Retrograde endocannabinoid signaling	70/1175	175/7206	4.72192832859e-14
ko04721	Synaptic vesicle cycle	42/1175	80/7206	7.35001245436e-14
ko04921	Oxytocin signaling pathway	76/1175	209/7206	1.27624595207e-12
ko05031	Amphetamine addiction	41/1175	91/7206	8.44513798435e-11
ko04911	Insulin secretion	48/1175	117/7206	1.20630750659e-10
ko04726	Serotonergic synapse	53/1175	137/7206	1.99257843678e-10
ko03010	Ribosome	1/1175	129/7206	4.10263300775e-09
ko04742	Taste transduction	29/1175	61/7206	1.10602276088e-08
ko04744	Phototransduction	21/1175	36/7206	1.1417553011e-08
ko04970	Salivary secretion	38/1175	95/7206	2.40869989989e-08
ko04720	Long-term potentiation	39/1175	99/7206	2.60277523461e-08
ko04261	Adrenergic signaling in cardiomyocytes	65/1175	205/7206	2.68537671654e-08
ko05322	Systemic lupus erythematosus	4/1175	151/7206	8.86630387404e-08
ko04022	cGMP-PKG signaling pathway	66/1175	216/7206	1.07256850382e-07
ko03040	Spliceosome	4/1175	145/7206	2.95474293167e-07
ko04925	Aldosterone synthesis and secretion	38/1175	105/7206	6.68078229712e-07
ko04971	Gastric acid secretion	36/1175	98/7206	1.16257474723e-06
ko05203	Viral carcinogenesis	19/1175	277/7206	2.73870125604e-06
ko05030	Cocaine addiction	28/1175	73/7206	6.59534300451e-06
ko04110	Cell cycle	6/1175	145/7206	6.86850468416e-06
ko03013	RNA transport	8/1175	166/7206	9.28122365478e-06
ko04730	Long-term depression	28/1175	78/7206	2.03011102934e-05
ko04070	Phosphatidylinositol signaling system	36/1175	112/7206	2.69146365766e-05
ko04922	Glucagon signaling pathway	40/1175	128/7206	2.78605769511e-05
ko04745	Phototransduction - fly	17/1175	38/7206	3.38550523154e-05
ko04710	Circadian rhythm	18/1175	43/7206	5.92511427009e-05
ko04966	Collecting duct acid secretion	13/1175	26/7206	6.93072650017e-05
ko04072	Phospholipase D signaling pathway	54/1175	197/7206	7.59537486519e-05
ko04371	Apelin signaling pathway	49/1175	177/7206	0.000114882195782
ko03008	Ribosome biogenesis in eukaryotes	2/1175	79/7206	0.00017159569126
ko04010	MAPK signaling pathway	77/1175	321/7206	0.000265697764038
ko04750	Inflammatory mediator regulation of TRP channels	36/1175	122/7206	0.000268467864681
ko05168	Herpes simplex infection	13/1175	182/7206	0.000331776111021
ko04014	Ras signaling pathway	68/1175	279/7206	0.000477317516976
ko04924	Renin secretion	27/1175	86/7206	0.000556663978962
ko05014	Amyotrophic lateral sclerosis (ALS)	24/1175	74/7206	0.000659112462183
ko05110	Vibrio cholerae infection	21/1175	63/7206	0.000835223770883
ko04270	Vascular smooth muscle contraction	41/1175	154/7206	0.000890481862577
ko04120	Ubiquitin mediated proteolysis	9/1175	138/7206	0.00098436496726
ko05169	Epstein-Barr virus infection	17/1175	206/7206	0.00104523658694
ko04740	Olfactory transduction	25/1175	80/7206	0.00110277467078
ko00520	Amino sugar and nucleotide sugar metabolism	1/1175	55/7206	0.00135565665644
ko04915	Estrogen signaling pathway	35/1175	131/7206	0.00256244162742
ko05219	Bladder cancer	1/1175	48/7206	0.00295239968669
ko04141	Protein processing in endoplasmic reticulum	16/1175	184/7206	0.0032483428059
ko04514	Cell adhesion molecules (CAMs)	34/1175	130/7206	0.0037685084512
ko04060	Cytokine-cytokine receptor interaction	17/1175	191/7206	0.00381204137095
ko04972	Pancreatic secretion	30/1175	111/7206	0.00399278155531
ko03420	Nucleotide excision repair	1/1175	46/7206	0.0044224828294
ko04626	Plant-pathogen interaction	8/1175	18/7206	0.00459533366989
ko05161	Hepatitis B	15/1175	173/7206	0.00467592211684
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/1175	79/7206	0.00510494236806
ko04540	Gap junction	33/1175	128/7206	0.00527643889624
ko05205	Proteoglycans in cancer	28/1175	271/7206	0.00554444015318
ko04360	Axon guidance	54/1175	233/7206	0.00658175282992
ko03022	Basal transcription factors	1/1175	44/7206	0.00668565214836
ko05144	Malaria	1/1175	45/7206	0.00696239903118
ko05164	Influenza A	15/1175	167/7206	0.00780528877683
ko04214	Apoptosis - fly	4/1175	72/7206	0.00964411219347
ko04623	Cytosolic DNA-sensing pathway	1/1175	41/7206	0.00995422724447
ko04711	Circadian rhythm - fly	6/1175	13/7206	0.0113083702681
ko04064	NF-kappa B signaling pathway	7/1175	96/7206	0.0121649221342
ko04923	Regulation of lipolysis in adipocytes	21/1175	77/7206	0.0126692425751
ko05133	Pertussis	6/1175	87/7206	0.0128314845226
ko03410	Base excision repair	1/1175	38/7206	0.0149025968667
ko04960	Aldosterone-regulated sodium reabsorption	13/1175	41/7206	0.0167973721331
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1175	14/7206	0.0171042403361
ko05140	Leishmaniasis	5/1175	75/7206	0.0183500135929
ko04260	Cardiac muscle contraction	25/1175	98/7206	0.0184572981077
ko04964	Proximal tubule bicarbonate reclamation	10/1175	29/7206	0.0187615504315
ko00562	Inositol phosphate metabolism	23/1175	89/7206	0.0200232241751
ko04621	NOD-like receptor signaling pathway	15/1175	157/7206	0.0211599472956
ko04630	Jak-STAT signaling pathway	12/1175	132/7206	0.0232047111355
ko05131	Shigellosis	6/1175	82/7206	0.0236471784148
ko00280	Valine, leucine and isoleucine degradation	3/1175	54/7206	0.026502225025
ko05414	Dilated cardiomyopathy	27/1175	112/7206	0.0284195000382
ko04916	Melanogenesis	33/1175	142/7206	0.0288882066282
ko00120	Primary bile acid biosynthesis	7/1175	20/7206	0.0331528604084
ko05162	Measles	11/1175	120/7206	0.0334066703195
ko00860	Porphyrin and chlorophyll metabolism	1/1175	34/7206	0.0334923762436
ko04113	Meiosis - yeast	5/1175	70/7206	0.0342553353568
ko04622	RIG-I-like receptor signaling pathway	4/1175	62/7206	0.0365617489579
ko00240	Pyrimidine metabolism	10/1175	110/7206	0.0372833143152
ko00010	Glycolysis / Gluconeogenesis	19/1175	74/7206	0.0381869106274
ko04930	Type II diabetes mellitus	15/1175	54/7206	0.0391353299152
ko04657	IL-17 signaling pathway	7/1175	87/7206	0.0395139813457
ko05410	Hypertrophic cardiomyopathy (HCM)	24/1175	100/7206	0.0408757138665
ko05010	Alzheimer's disease	44/1175	202/7206	0.0418008210371
ko05130	Pathogenic Escherichia coli infection	6/1175	77/7206	0.0428795144742
ko04612	Antigen processing and presentation	6/1175	77/7206	0.0428795144742
ko05166	HTLV-I infection	35/1175	292/7206	0.0429375643566
ko05231	Choline metabolism in cancer	31/1175	134/7206	0.0436835251456