ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	147/1064	423/7206	2.19195742817e-26
ko04020	Calcium signaling pathway	93/1064	265/7206	4.2673894114e-17
ko05033	Nicotine addiction	35/1064	56/7206	2.97150894594e-16
ko04724	Glutamatergic synapse	62/1064	152/7206	2.73827912901e-15
ko04713	Circadian entrainment	54/1064	136/7206	6.6410904474e-13
ko04024	cAMP signaling pathway	84/1064	279/7206	2.2405632635e-11
ko04727	GABAergic synapse	44/1064	110/7206	7.05432197304e-11
ko05032	Morphine addiction	44/1064	110/7206	7.05432197304e-11
ko04921	Oxytocin signaling pathway	65/1064	209/7206	1.09037153907e-09
ko04725	Cholinergic synapse	52/1064	160/7206	1.12450384193e-08
ko04022	cGMP-PKG signaling pathway	64/1064	216/7206	1.37432987055e-08
ko04911	Insulin secretion	41/1064	117/7206	3.73532589406e-08
ko03040	Spliceosome	2/1064	145/7206	4.08921952215e-08
ko03010	Ribosome	1/1064	129/7206	4.63899955638e-08
ko04726	Serotonergic synapse	45/1064	137/7206	6.83589472254e-08
ko04970	Salivary secretion	35/1064	95/7206	7.59506927909e-08
ko04721	Synaptic vesicle cycle	31/1064	80/7206	1.1130795467e-07
ko04723	Retrograde endocannabinoid signaling	52/1064	175/7206	3.74207762643e-07
ko03013	RNA transport	5/1064	166/7206	7.12045897289e-07
ko04728	Dopaminergic synapse	53/1064	185/7206	8.50884639505e-07
ko04720	Long-term potentiation	34/1064	99/7206	9.20070813097e-07
ko04261	Adrenergic signaling in cardiomyocytes	57/1064	205/7206	1.05623225047e-06
ko05322	Systemic lupus erythematosus	4/1064	151/7206	1.14894501732e-06
ko04925	Aldosterone synthesis and secretion	35/1064	105/7206	1.27947738949e-06
ko04971	Gastric acid secretion	33/1064	98/7206	2.06037999642e-06
ko04110	Cell cycle	4/1064	145/7206	2.45509025631e-06
ko04742	Taste transduction	23/1064	61/7206	8.32567634816e-06
ko05203	Viral carcinogenesis	17/1064	277/7206	8.61944079432e-06
ko05031	Amphetamine addiction	30/1064	91/7206	9.5102201306e-06
ko04070	Phosphatidylinositol signaling system	34/1064	112/7206	2.07437286293e-05
ko04730	Long-term depression	26/1064	78/7206	3.2155097915e-05
ko04072	Phospholipase D signaling pathway	51/1064	197/7206	3.68446510164e-05
ko04710	Circadian rhythm	17/1064	43/7206	6.20738268385e-05
ko04750	Inflammatory mediator regulation of TRP channels	34/1064	122/7206	0.000150672344878
ko04745	Phototransduction - fly	15/1064	38/7206	0.000170819376839
ko04922	Glucagon signaling pathway	35/1064	128/7206	0.000208662001633
ko04270	Vascular smooth muscle contraction	40/1064	154/7206	0.000211987400355
ko04744	Phototransduction	14/1064	36/7206	0.000337270432847
ko04972	Pancreatic secretion	30/1064	111/7206	0.000651240943018
ko04010	MAPK signaling pathway	69/1064	321/7206	0.000917234726689
ko05168	Herpes simplex infection	12/1064	182/7206	0.000936487474184
ko04014	Ras signaling pathway	61/1064	279/7206	0.00135859708586
ko04930	Type II diabetes mellitus	17/1064	54/7206	0.00157593395378
ko04260	Cardiac muscle contraction	26/1064	98/7206	0.00225128412679
ko04626	Plant-pathogen interaction	8/1064	18/7206	0.00242062876895
ko05169	Epstein-Barr virus infection	16/1064	206/7206	0.00269501640978
ko03050	Proteasome	1/1064	54/7206	0.00320901646433
ko04924	Renin secretion	23/1064	86/7206	0.00330568913232
ko00520	Amino sugar and nucleotide sugar metabolism	1/1064	55/7206	0.00332019873847
ko04141	Protein processing in endoplasmic reticulum	14/1064	184/7206	0.00424473359952
ko05224	Breast cancer	13/1064	174/7206	0.00464941575586
ko04657	IL-17 signaling pathway	4/1064	87/7206	0.00545232854585
ko04514	Cell adhesion molecules (CAMs)	31/1064	130/7206	0.00563930779631
ko04960	Aldosterone-regulated sodium reabsorption	13/1064	41/7206	0.00604877111615
ko04964	Proximal tubule bicarbonate reclamation	10/1064	29/7206	0.00652327207146
ko05164	Influenza A	13/1064	167/7206	0.00785268223032
ko04371	Apelin signaling pathway	39/1064	177/7206	0.00955991061534
ko04111	Cell cycle - yeast	5/1064	90/7206	0.0103109555724
ko04120	Ubiquitin mediated proteolysis	10/1064	138/7206	0.0104078834697
ko03420	Nucleotide excision repair	1/1064	46/7206	0.0107491760852
ko05030	Cocaine addiction	19/1064	73/7206	0.0116149468474
ko05130	Pathogenic Escherichia coli infection	4/1064	77/7206	0.0144016780892
ko05217	Basal cell carcinoma	3/1064	68/7206	0.0145803210042
ko04976	Bile secretion	20/1064	80/7206	0.0160718696653
ko03015	mRNA surveillance pathway	6/1064	93/7206	0.0184308814103
ko04011	MAPK signaling pathway - yeast	2/1064	53/7206	0.0186104818945
ko04550	Signaling pathways regulating pluripotency of stem cells	14/1064	165/7206	0.0194086848053
ko00120	Primary bile acid biosynthesis	7/1064	20/7206	0.0200765479776
ko05200	Pathways in cancer	55/1064	492/7206	0.0209994165994
ko00564	Glycerophospholipid metabolism	23/1064	99/7206	0.0219477643298
ko04923	Regulation of lipolysis in adipocytes	19/1064	77/7206	0.0221031032084
ko05205	Proteoglycans in cancer	27/1064	271/7206	0.022922693762
ko04623	Cytosolic DNA-sensing pathway	1/1064	41/7206	0.0241995045602
ko04217	Necroptosis	16/1064	178/7206	0.0247166913097
ko00680	Methane metabolism	10/1064	34/7206	0.0257218788106
ko05131	Shigellosis	5/1064	82/7206	0.0268505016167
ko04113	Meiosis - yeast	4/1064	70/7206	0.0274752696273
ko04214	Apoptosis - fly	4/1064	72/7206	0.0281145173079
ko05014	Amyotrophic lateral sclerosis (ALS)	18/1064	74/7206	0.0302948962137
ko04540	Gap junction	28/1064	128/7206	0.0314550041667
ko04711	Circadian rhythm - fly	5/1064	13/7206	0.0319928327385
ko05133	Pertussis	6/1064	87/7206	0.0333935278519
ko04341	Hedgehog signaling pathway - fly	1/1064	38/7206	0.0355599167091
ko03410	Base excision repair	1/1064	38/7206	0.0355599167091
ko04612	Antigen processing and presentation	5/1064	77/7206	0.0358354107031
ko04360	Axon guidance	46/1064	233/7206	0.0382512864164
ko05161	Hepatitis B	16/1064	173/7206	0.0388470632588
ko04621	NOD-like receptor signaling pathway	14/1064	157/7206	0.0397739020302
ko04919	Thyroid hormone signaling pathway	30/1064	143/7206	0.0421637510972
ko05166	HTLV-I infection	31/1064	292/7206	0.042950972109
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/1064	14/7206	0.0438761190151
ko04973	Carbohydrate digestion and absorption	11/1064	42/7206	0.0473065228455
ko04520	Adherens junction	8/1064	103/7206	0.0487941006271
ko00562	Inositol phosphate metabolism	20/1064	89/7206	0.0492416898126