ko pathway ratio_in_study ratio_in_pop p_value ko04658 Th1 and Th2 cell differentiation 13/129 96/7206 1.20749603372e-08 ko05168 Herpes simplex infection 17/129 182/7206 1.97099716995e-08 ko05162 Measles 14/129 120/7206 2.28955281935e-08 ko05164 Influenza A 16/129 167/7206 3.71723107211e-08 ko04659 Th17 cell differentiation 13/129 106/7206 4.09148941966e-08 ko04621 NOD-like receptor signaling pathway 15/129 157/7206 1.06319028718e-07 ko04060 Cytokine-cytokine receptor interaction 16/129 191/7206 2.44230353807e-07 ko05145 Toxoplasmosis 13/129 126/7206 3.24203953978e-07 ko05340 Primary immunodeficiency 7/129 30/7206 7.23310902274e-07 ko04380 Osteoclast differentiation 12/129 134/7206 4.27907046876e-06 ko04650 Natural killer cell mediated cytotoxicity 10/129 97/7206 8.01263582706e-06 ko04612 Antigen processing and presentation 9/129 77/7206 8.24168567317e-06 ko04620 Toll-like receptor signaling pathway 10/129 100/7206 1.0539331798e-05 ko04660 T cell receptor signaling pathway 11/129 124/7206 1.19975980652e-05 ko04622 RIG-I-like receptor signaling pathway 8/129 62/7206 1.27466308477e-05 ko04630 Jak-STAT signaling pathway 11/129 132/7206 2.17504143455e-05 ko05140 Leishmaniasis 8/129 75/7206 5.23484851854e-05 ko05161 Hepatitis B 12/129 173/7206 5.70790872844e-05 ko05152 Tuberculosis 12/129 187/7206 0.000120985803033 ko05133 Pertussis 8/129 87/7206 0.000151516070464 ko04064 NF-kappa B signaling pathway 8/129 96/7206 0.000300565891677 ko03050 Proteasome 6/129 54/7206 0.000374202471095 ko05160 Hepatitis C 10/129 153/7206 0.000392122042569 ko05150 Staphylococcus aureus infection 5/129 36/7206 0.000410837229576 ko05321 Inflammatory bowel disease (IBD) 6/129 56/7206 0.000456890898054 ko04672 Intestinal immune network for IgA production 5/129 37/7206 0.000468281440125 ko04610 Complement and coagulation cascades 7/129 79/7206 0.000497648941129 ko05167 Kaposi's sarcoma-associated herpesvirus infection 11/129 191/7206 0.000592941010994 ko04623 Cytosolic DNA-sensing pathway 5/129 41/7206 0.000760324646084 ko05330 Allograft rejection 4/129 24/7206 0.000788935953619 ko04062 Chemokine signaling pathway 11/129 201/7206 0.000906901194849 ko05320 Autoimmune thyroid disease 4/129 29/7206 0.00164559769927 ko05166 HTLV-I infection 13/129 292/7206 0.00209993243522 ko05416 Viral myocarditis 5/129 55/7206 0.00289112292899 ko05310 Asthma 3/129 17/7206 0.00317196277318 ko05131 Shigellosis 6/129 82/7206 0.00337588898325 ko05332 Graft-versus-host disease 3/129 18/7206 0.00375697400837 ko04666 Fc gamma R-mediated phagocytosis 7/129 122/7206 0.00610559953927 ko05202 Transcriptional misregulation in cancer 9/129 188/7206 0.00642788538438 ko04145 Phagosome 8/129 162/7206 0.0083880401419 ko05142 Chagas disease (American trypanosomiasis) 7/129 130/7206 0.00856444025583 ko05169 Epstein-Barr virus infection 9/129 206/7206 0.0113880300166 ko04217 Necroptosis 8/129 178/7206 0.0142972981508 ko04940 Type I diabetes mellitus 3/129 32/7206 0.0190431270047 ko04668 TNF signaling pathway 6/129 120/7206 0.020365992274 ko04662 B cell receptor signaling pathway 5/129 88/7206 0.0204317993029 ko05323 Rheumatoid arthritis 5/129 89/7206 0.0213466434465 ko00760 Nicotinate and nicotinamide metabolism 3/129 34/7206 0.0223901221367 ko04514 Cell adhesion molecules (CAMs) 6/129 130/7206 0.0288189480638 ko05144 Malaria 3/129 45/7206 0.0461163783382 ko05215 Prostate cancer 5/129 111/7206 0.0485009056598 ko04664 Fc epsilon RI signaling pathway 4/129 77/7206 0.0487589826315 ko00120 Primary bile acid biosynthesis 2/129 20/7206 0.0489684736446