ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko00071	Fatty acid degradation	15/435	45/7206	2.61478051984e-08
ko00120	Primary bile acid biosynthesis	10/435	20/7206	6.20479767023e-08
ko01200	Carbon metabolism	25/435	128/7206	1.26573598246e-07
ko00360	Phenylalanine metabolism	9/435	17/7206	1.54540934549e-07
ko00350	Tyrosine metabolism	12/435	33/7206	2.23512308558e-07
ko00380	Tryptophan metabolism	14/435	50/7206	8.72768422531e-07
ko04146	Peroxisome	19/435	89/7206	1.02126111045e-06
ko03320	PPAR signaling pathway	16/435	69/7206	2.31928447202e-06
ko00500	Starch and sucrose metabolism	11/435	35/7206	3.80435704245e-06
ko00362	Benzoate degradation	5/435	6/7206	4.47242683559e-06
ko00950	Isoquinoline alkaloid biosynthesis	6/435	10/7206	7.97865892842e-06
ko00640	Propanoate metabolism	10/435	34/7206	2.04386308912e-05
ko01212	Fatty acid metabolism	13/435	60/7206	4.48406309624e-05
ko04974	Protein digestion and absorption	17/435	96/7206	5.08624393885e-05
ko00620	Pyruvate metabolism	11/435	46/7206	6.64262814271e-05
ko00020	Citrate cycle (TCA cycle)	9/435	35/7206	0.000168931213612
ko00330	Arginine and proline metabolism	12/435	61/7206	0.000233420391161
ko05034	Alcoholism	3/435	238/7206	0.000435679104832
ko00140	Steroid hormone biosynthesis	9/435	41/7206	0.000606561265104
ko00960	Tropane, piperidine and pyridine alkaloid biosynthesis	3/435	4/7206	0.000834904538254
ko00643	Styrene degradation	3/435	4/7206	0.000834904538254
ko03040	Spliceosome	1/435	145/7206	0.00222951380476
ko04610	Complement and coagulation cascades	12/435	79/7206	0.00255846191085
ko00720	Carbon fixation pathways in prokaryotes	5/435	17/7206	0.00264394591181
ko05203	Viral carcinogenesis	6/435	277/7206	0.00292950650098
ko04060	Cytokine-cytokine receptor interaction	22/435	191/7206	0.00303976431811
ko00130	Ubiquinone and other terpenoid-quinone biosynthesis	4/435	11/7206	0.00307490204625
ko00340	Histidine metabolism	6/435	25/7206	0.00309432640316
ko00983	Drug metabolism - other enzymes	8/435	42/7206	0.00316811374794
ko00310	Lysine degradation	11/435	73/7206	0.00406345562451
ko00561	Glycerolipid metabolism	10/435	63/7206	0.00413104957345
ko03013	RNA transport	2/435	166/7206	0.00431997848223
ko00592	alpha-Linolenic acid metabolism	5/435	19/7206	0.00449480681245
ko00010	Glycolysis / Gluconeogenesis	11/435	74/7206	0.00452136847057
ko04922	Glucagon signaling pathway	16/435	128/7206	0.00454163418848
ko00280	Valine, leucine and isoleucine degradation	9/435	54/7206	0.0045887150773
ko03010	Ribosome	1/435	129/7206	0.00467940504471
ko00982	Drug metabolism - cytochrome P450	7/435	37/7206	0.00590230639563
ko00630	Glyoxylate and dicarboxylate metabolism	7/435	38/7206	0.00686872201334
ko00260	Glycine, serine and threonine metabolism	8/435	48/7206	0.00738094760628
ko04380	Osteoclast differentiation	16/435	134/7206	0.00874605401082
ko00830	Retinol metabolism	7/435	42/7206	0.011934505399
ko00220	Arginine biosynthesis	5/435	24/7206	0.0128097157332
ko04710	Circadian rhythm	7/435	43/7206	0.0135372447871
ko05032	Morphine addiction	1/435	110/7206	0.0143734623536
ko01040	Biosynthesis of unsaturated fatty acids	5/435	25/7206	0.0152385630657
ko05012	Parkinson's disease	17/435	155/7206	0.0155257848989
ko00410	beta-Alanine metabolism	6/435	35/7206	0.0170344996187
ko04975	Fat digestion and absorption	6/435	35/7206	0.0170344996187
ko00040	Pentose and glucuronate interconversions	5/435	26/7206	0.0179569051759
ko00650	Butanoate metabolism	5/435	26/7206	0.0179569051759
ko00072	Synthesis and degradation of ketone bodies	3/435	10/7206	0.019061409179
ko05150	Staphylococcus aureus infection	6/435	36/7206	0.0194331600773
ko00471	D-Glutamine and D-glutamate metabolism	2/435	4/7206	0.0201082167853
ko00965	Betalain biosynthesis	2/435	4/7206	0.0201082167853
ko04614	Renin-angiotensin system	4/435	18/7206	0.0203747355663
ko00710	Carbon fixation in photosynthetic organisms	5/435	27/7206	0.0209770940866
ko04360	Axon guidance	6/435	233/7206	0.0238805749709
ko00250	Alanine, aspartate and glutamate metabolism	6/435	38/7206	0.024898906165
ko02010	ABC transporters	6/435	39/7206	0.0279809224749
ko05100	Bacterial invasion of epithelial cells	1/435	99/7206	0.0305922710879
ko00980	Metabolism of xenobiotics by cytochrome P450	6/435	40/7206	0.031304564371
ko05340	Primary immunodeficiency	5/435	30/7206	0.0319522973402
ko00400	Phenylalanine, tyrosine and tryptophan biosynthesis	2/435	5/7206	0.0321845891453
ko00281	Geraniol degradation	2/435	5/7206	0.0321845891453
ko05162	Measles	13/435	120/7206	0.0330982655076
ko00100	Steroid biosynthesis	4/435	21/7206	0.0345641801268
ko04659	Th17 cell differentiation	12/435	106/7206	0.035685306475
ko05322	Systemic lupus erythematosus	3/435	151/7206	0.0357571634704
ko01230	Biosynthesis of amino acids	10/435	85/7206	0.0361265267155
ko00053	Ascorbate and aldarate metabolism	4/435	22/7206	0.0402973285402
ko04111	Cell cycle - yeast	1/435	90/7206	0.043378625007
ko05120	Epithelial cell signaling in Helicobacter pylori infection	1/435	92/7206	0.0439581567242
ko04080	Neuroactive ligand-receptor interaction	16/435	423/7206	0.0451138152911
ko04020	Calcium signaling pathway	24/435	265/7206	0.0470759325511