ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	94/662	423/7206	8.04714877684e-17
ko04724	Glutamatergic synapse	50/662	152/7206	1.4465905976e-16
ko04721	Synaptic vesicle cycle	35/662	80/7206	2.36330036804e-16
ko05032	Morphine addiction	41/662	110/7206	5.97993678847e-16
ko04713	Circadian entrainment	44/662	136/7206	2.04028301155e-14
ko05033	Nicotine addiction	27/662	56/7206	3.45615033276e-14
ko04727	GABAergic synapse	38/662	110/7206	1.22862454462e-13
ko04728	Dopaminergic synapse	51/662	185/7206	2.18840473673e-13
ko04723	Retrograde endocannabinoid signaling	47/662	175/7206	5.57622701607e-12
ko04024	cAMP signaling pathway	63/662	279/7206	7.09424232757e-12
ko04921	Oxytocin signaling pathway	51/662	209/7206	3.42293238468e-11
ko04911	Insulin secretion	34/662	117/7206	5.35419340396e-10
ko04725	Cholinergic synapse	38/662	160/7206	2.62248185395e-08
ko04966	Collecting duct acid secretion	13/662	26/7206	9.96541073265e-08
ko04726	Serotonergic synapse	33/662	137/7206	1.53886383836e-07
ko04744	Phototransduction	15/662	36/7206	2.13085786449e-07
ko04261	Adrenergic signaling in cardiomyocytes	42/662	205/7206	4.63338398013e-07
ko04742	Taste transduction	19/662	61/7206	1.13311257349e-06
ko04020	Calcium signaling pathway	49/662	265/7206	1.96894405907e-06
ko05031	Amphetamine addiction	23/662	91/7206	4.99116464291e-06
ko04972	Pancreatic secretion	26/662	111/7206	5.60828542014e-06
ko04970	Salivary secretion	23/662	95/7206	1.08370058038e-05
ko05322	Systemic lupus erythematosus	1/662	151/7206	1.16039571417e-05
ko04971	Gastric acid secretion	23/662	98/7206	1.8716315004e-05
ko04720	Long-term potentiation	23/662	99/7206	2.2315549517e-05
ko03040	Spliceosome	1/662	145/7206	2.74728682283e-05
ko05110	Vibrio cholerae infection	17/662	63/7206	3.44421717722e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	18/662	74/7206	9.11848155692e-05
ko05030	Cocaine addiction	17/662	73/7206	0.000250701012353
ko05120	Epithelial cell signaling in Helicobacter pylori infection	20/662	92/7206	0.00033404076465
ko05203	Viral carcinogenesis	10/662	277/7206	0.000414919466489
ko04925	Aldosterone synthesis and secretion	21/662	105/7206	0.000509595205857
ko04730	Long-term depression	17/662	78/7206	0.000575293591108
ko04964	Proximal tubule bicarbonate reclamation	9/662	29/7206	0.000820170381166
ko03013	RNA transport	4/662	166/7206	0.000913574818362
ko04010	MAPK signaling pathway	47/662	321/7206	0.00105419758923
ko04110	Cell cycle	3/662	145/7206	0.00113310598266
ko05162	Measles	2/662	120/7206	0.0012553363131
ko04070	Phosphatidylinositol signaling system	21/662	112/7206	0.00137914675593
ko04745	Phototransduction - fly	10/662	38/7206	0.00175602996216
ko05169	Epstein-Barr virus infection	7/662	206/7206	0.00198311765237
ko04060	Cytokine-cytokine receptor interaction	6/662	191/7206	0.00202189389737
ko04750	Inflammatory mediator regulation of TRP channels	22/662	122/7206	0.00214980258481
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/662	59/7206	0.00224445524488
ko04976	Bile secretion	16/662	80/7206	0.00259288036706
ko05164	Influenza A	5/662	167/7206	0.00259876398355
ko05168	Herpes simplex infection	6/662	182/7206	0.00265655773209
ko00680	Methane metabolism	9/662	34/7206	0.00283088137643
ko04022	cGMP-PKG signaling pathway	33/662	216/7206	0.00372335996974
ko04260	Cardiac muscle contraction	18/662	98/7206	0.00399813924102
ko05161	Hepatitis B	6/662	173/7206	0.00492955103371
ko04120	Ubiquitin mediated proteolysis	4/662	138/7206	0.00668247390482
ko04924	Renin secretion	16/662	86/7206	0.00696717691456
ko00010	Glycolysis / Gluconeogenesis	14/662	74/7206	0.00748057637824
ko05323	Rheumatoid arthritis	16/662	89/7206	0.00832304930737
ko04071	Sphingolipid signaling pathway	25/662	162/7206	0.00855940322467
ko04145	Phagosome	25/662	162/7206	0.00855940322467
ko04510	Focal adhesion	11/662	240/7206	0.00877311306536
ko04072	Phospholipase D signaling pathway	29/662	197/7206	0.0115785182505
ko05215	Prostate cancer	3/662	111/7206	0.0121429810075
ko05166	HTLV-I infection	15/662	292/7206	0.0126572429802
ko04915	Estrogen signaling pathway	21/662	131/7206	0.0132533461058
ko05140	Leishmaniasis	1/662	75/7206	0.0136339784479
ko04014	Ras signaling pathway	38/662	279/7206	0.0144311673222
ko04710	Circadian rhythm	9/662	43/7206	0.0144617401491
ko00190	Oxidative phosphorylation	20/662	127/7206	0.0184379025699
ko04922	Glucagon signaling pathway	20/662	128/7206	0.0189646119542
ko04540	Gap junction	20/662	128/7206	0.0189646119542
ko04626	Plant-pathogen interaction	5/662	18/7206	0.0200866450991
ko04514	Cell adhesion molecules (CAMs)	20/662	130/7206	0.0203096978681
ko00030	Pentose phosphate pathway	7/662	32/7206	0.0235512826186
ko04350	TGF-beta signaling pathway	3/662	103/7206	0.0238068763418
ko00562	Inositol phosphate metabolism	15/662	89/7206	0.0239664431049
ko04978	Mineral absorption	8/662	40/7206	0.0266672416936
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	13/662	79/7206	0.0311310155371
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/662	14/7206	0.0334962700337
ko01230	Biosynthesis of amino acids	14/662	85/7206	0.0343609278265
ko04660	T cell receptor signaling pathway	5/662	124/7206	0.0412851306027
ko04330	Notch signaling pathway	1/662	62/7206	0.042310647281
ko00290	Valine, leucine and isoleucine biosynthesis	2/662	4/7206	0.0446035121865
ko05414	Dilated cardiomyopathy	17/662	112/7206	0.0452343116152
ko04371	Apelin signaling pathway	24/662	177/7206	0.0476069020798
ko04960	Aldosterone-regulated sodium reabsorption	8/662	41/7206	0.0495790303709