ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	188/1207	423/7206	1.23862981873e-43
ko04724	Glutamatergic synapse	86/1207	152/7206	1.85462867885e-29
ko05033	Nicotine addiction	45/1207	56/7206	1.33853637436e-25
ko05032	Morphine addiction	66/1207	110/7206	7.73806018712e-25
ko04713	Circadian entrainment	74/1207	136/7206	4.87550942658e-24
ko04727	GABAergic synapse	62/1207	110/7206	2.15652963925e-21
ko04728	Dopaminergic synapse	80/1207	185/7206	7.66895231918e-18
ko04024	cAMP signaling pathway	105/1207	279/7206	1.08902176611e-17
ko04725	Cholinergic synapse	72/1207	160/7206	2.56874784294e-17
ko04020	Calcium signaling pathway	100/1207	265/7206	6.09037371585e-17
ko04723	Retrograde endocannabinoid signaling	75/1207	175/7206	1.57045769992e-16
ko04921	Oxytocin signaling pathway	81/1207	209/7206	1.0497593633e-14
ko04721	Synaptic vesicle cycle	43/1207	80/7206	3.25646051482e-14
ko04911	Insulin secretion	53/1207	117/7206	3.27912860197e-13
ko04726	Serotonergic synapse	57/1207	137/7206	3.33204830243e-12
ko04742	Taste transduction	33/1207	61/7206	2.58857335579e-11
ko04360	Axon guidance	79/1207	233/7206	8.57231742759e-11
ko04261	Adrenergic signaling in cardiomyocytes	72/1207	205/7206	1.1166799638e-10
ko05031	Amphetamine addiction	40/1207	91/7206	8.3162643181e-10
ko03040	Spliceosome	2/1207	145/7206	1.56398282029e-09
ko03010	Ribosome	1/1207	129/7206	2.60363762462e-09
ko04720	Long-term potentiation	41/1207	99/7206	4.48152947975e-09
ko04744	Phototransduction	21/1207	36/7206	1.87117281981e-08
ko04022	cGMP-PKG signaling pathway	69/1207	216/7206	2.60135880334e-08
ko04970	Salivary secretion	38/1207	95/7206	7.48345042356e-08
ko04010	MAPK signaling pathway	91/1207	321/7206	9.8116419241e-08
ko04072	Phospholipase D signaling pathway	62/1207	197/7206	2.94982033316e-07
ko05322	Systemic lupus erythematosus	5/1207	151/7206	3.85960397501e-07
ko04925	Aldosterone synthesis and secretion	39/1207	105/7206	4.33030657598e-07
ko04014	Ras signaling pathway	79/1207	279/7206	7.42891344134e-07
ko03013	RNA transport	7/1207	166/7206	8.52164362907e-07
ko04070	Phosphatidylinositol signaling system	40/1207	112/7206	1.10601870442e-06
ko04730	Long-term depression	31/1207	78/7206	1.58659898344e-06
ko05168	Herpes simplex infection	10/1207	182/7206	7.08032573584e-06
ko05030	Cocaine addiction	28/1207	73/7206	9.07249226667e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	28/1207	74/7206	1.15465461921e-05
ko03008	Ribosome biogenesis in eukaryotes	1/1207	79/7206	1.26725829361e-05
ko04514	Cell adhesion molecules (CAMs)	42/1207	130/7206	1.30470582033e-05
ko04971	Gastric acid secretion	34/1207	98/7206	1.42119757835e-05
ko05203	Viral carcinogenesis	22/1207	277/7206	1.7787990108e-05
ko04540	Gap junction	41/1207	128/7206	1.98519620368e-05
ko04915	Estrogen signaling pathway	40/1207	131/7206	7.74275520655e-05
ko04972	Pancreatic secretion	35/1207	111/7206	9.86204828614e-05
ko04120	Ubiquitin mediated proteolysis	8/1207	138/7206	0.000188546233261
ko04745	Phototransduction - fly	16/1207	38/7206	0.000193637868894
ko04371	Apelin signaling pathway	49/1207	177/7206	0.000213338942141
ko04710	Circadian rhythm	17/1207	43/7206	0.000306350036859
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	26/1207	79/7206	0.000380466457338
ko04141	Protein processing in endoplasmic reticulum	14/1207	184/7206	0.000412060463927
ko04740	Olfactory transduction	26/1207	80/7206	0.000448316936813
ko04621	NOD-like receptor signaling pathway	11/1207	157/7206	0.000477345588473
ko04750	Inflammatory mediator regulation of TRP channels	36/1207	122/7206	0.000513385746381
ko04015	Rap1 signaling pathway	69/1207	278/7206	0.000538239051936
ko05231	Choline metabolism in cancer	38/1207	134/7206	0.000637642068489
ko04146	Peroxisome	4/1207	89/7206	0.000826917476897
ko04930	Type II diabetes mellitus	19/1207	54/7206	0.000830140704912
ko05164	Influenza A	13/1207	167/7206	0.00104622439985
ko04626	Plant-pathogen interaction	9/1207	18/7206	0.00115510902029
ko04110	Cell cycle	11/1207	145/7206	0.00157473932473
ko04923	Regulation of lipolysis in adipocytes	24/1207	77/7206	0.00177005040301
ko00240	Pyrimidine metabolism	7/1207	110/7206	0.00182823248317
ko04924	Renin secretion	26/1207	86/7206	0.0019273924748
ko05414	Dilated cardiomyopathy	32/1207	112/7206	0.00193136375948
ko05214	Glioma	24/1207	79/7206	0.00224001193301
ko04612	Antigen processing and presentation	4/1207	77/7206	0.00335239959743
ko04976	Bile secretion	24/1207	80/7206	0.00363315232546
ko04260	Cardiac muscle contraction	28/1207	98/7206	0.00375268012322
ko04060	Cytokine-cytokine receptor interaction	18/1207	191/7206	0.00431843407408
ko00071	Fatty acid degradation	1/1207	45/7206	0.00433068858039
ko05169	Epstein-Barr virus infection	20/1207	206/7206	0.00443492537525
ko03420	Nucleotide excision repair	1/1207	46/7206	0.00446617269236
ko04964	Proximal tubule bicarbonate reclamation	11/1207	29/7206	0.0051276849185
ko04960	Aldosterone-regulated sodium reabsorption	14/1207	41/7206	0.00562807245688
ko04270	Vascular smooth muscle contraction	39/1207	154/7206	0.0061086829662
ko04966	Collecting duct acid secretion	10/1207	26/7206	0.00671313765308
ko03022	Basal transcription factors	1/1207	44/7206	0.00689652264893
ko04961	Endocrine and other factor-regulated calcium reabsorption	18/1207	59/7206	0.0078733415027
ko04064	NF-kappa B signaling pathway	7/1207	96/7206	0.00882880237207
ko04622	RIG-I-like receptor signaling pathway	3/1207	62/7206	0.00927721666049
ko04610	Complement and coagulation cascades	5/1207	79/7206	0.00946322804153
ko05410	Hypertrophic cardiomyopathy (HCM)	27/1207	100/7206	0.00968131549503
ko00980	Metabolism of xenobiotics by cytochrome P450	1/1207	40/7206	0.00977347184179
ko05230	Central carbon metabolism in cancer	23/1207	81/7206	0.0099595640482
ko04973	Carbohydrate digestion and absorption	14/1207	42/7206	0.0106967265111
ko00380	Tryptophan metabolism	2/1207	50/7206	0.0120690722274
ko04711	Circadian rhythm - fly	6/1207	13/7206	0.0128949914267
ko04722	Neurotrophin signaling pathway	39/1207	160/7206	0.0132878219285
ko04666	Fc gamma R-mediated phagocytosis	31/1207	122/7206	0.0139184086993
ko04071	Sphingolipid signaling pathway	39/1207	162/7206	0.0142964928369
ko04217	Necroptosis	18/1207	178/7206	0.0144936428052
ko00982	Drug metabolism - cytochrome P450	1/1207	37/7206	0.0146518200886
ko03410	Base excision repair	1/1207	38/7206	0.0147715516633
ko04922	Glucagon signaling pathway	32/1207	128/7206	0.0163238680941
ko04115	p53 signaling pathway	5/1207	74/7206	0.0180815244336
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1207	14/7206	0.0194231095912
ko05205	Proteoglycans in cancer	32/1207	271/7206	0.0250808179355
ko05144	Malaria	2/1207	45/7206	0.0254712790594
ko05162	Measles	11/1207	120/7206	0.0256508784147
ko00280	Valine, leucine and isoleucine degradation	3/1207	54/7206	0.0264005521013
ko04912	GnRH signaling pathway	30/1207	122/7206	0.0268222965615
ko04012	ErbB signaling pathway	27/1207	109/7206	0.027990621472
ko04114	Oocyte meiosis	33/1207	139/7206	0.0293847733473
ko04916	Melanogenesis	34/1207	142/7206	0.0301573105546
ko00562	Inositol phosphate metabolism	23/1207	89/7206	0.0307218491818
ko04919	Thyroid hormone signaling pathway	34/1207	143/7206	0.03080805613
ko03320	PPAR signaling pathway	5/1207	69/7206	0.0339754579021
ko04113	Meiosis - yeast	5/1207	70/7206	0.0346629550678
ko00330	Arginine and proline metabolism	4/1207	61/7206	0.0366450457793
ko00590	Arachidonic acid metabolism	3/1207	52/7206	0.037809794323
ko03018	RNA degradation	7/1207	84/7206	0.0386757139529
ko05110	Vibrio cholerae infection	17/1207	63/7206	0.0400516533638
ko05210	Colorectal cancer	22/1207	86/7206	0.0402899072068
ko05140	Leishmaniasis	6/1207	75/7206	0.0423708911712
ko04142	Lysosome	16/1207	151/7206	0.0465282106905
ko00512	Mucin type O-glycan biosynthesis	9/1207	29/7206	0.0470121134267
ko05340	Primary immunodeficiency	1/1207	30/7206	0.0486680612182