ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	128/606	423/7206	5.67920834609e-42
ko04724	Glutamatergic synapse	65/606	152/7206	4.18793902089e-31
ko05033	Nicotine addiction	38/606	56/7206	2.33296240654e-28
ko04727	GABAergic synapse	48/606	110/7206	1.23166834193e-23
ko05032	Morphine addiction	47/606	110/7206	1.10275015917e-22
ko04723	Retrograde endocannabinoid signaling	55/606	175/7206	7.04913653849e-19
ko04713	Circadian entrainment	45/606	136/7206	1.37098010411e-16
ko04728	Dopaminergic synapse	51/606	185/7206	6.14067175241e-15
ko04020	Calcium signaling pathway	60/606	265/7206	3.72907132727e-13
ko05030	Cocaine addiction	28/606	73/7206	1.40354567663e-12
ko04911	Insulin secretion	36/606	117/7206	1.97128860832e-12
ko05031	Amphetamine addiction	30/606	91/7206	2.04111892279e-11
ko04725	Cholinergic synapse	41/606	160/7206	4.04458821027e-11
ko04721	Synaptic vesicle cycle	26/606	80/7206	6.5165939981e-10
ko04024	cAMP signaling pathway	55/606	279/7206	1.45630076192e-09
ko04726	Serotonergic synapse	34/606	137/7206	4.82283542182e-09
ko04742	Taste transduction	21/606	61/7206	9.17358019784e-09
ko04720	Long-term potentiation	26/606	99/7206	9.42881994117e-08
ko05203	Viral carcinogenesis	3/606	277/7206	1.05321478181e-07
ko04921	Oxytocin signaling pathway	39/606	209/7206	1.54350639976e-06
ko04060	Cytokine-cytokine receptor interaction	1/606	191/7206	1.78464707935e-06
ko04072	Phospholipase D signaling pathway	36/606	197/7206	6.2801490689e-06
ko04970	Salivary secretion	22/606	95/7206	8.78724264629e-06
ko04925	Aldosterone synthesis and secretion	23/606	105/7206	1.47211124562e-05
ko04261	Adrenergic signaling in cardiomyocytes	36/606	205/7206	1.70743078476e-05
ko04010	MAPK signaling pathway	50/606	321/7206	1.84965510995e-05
ko04744	Phototransduction	12/606	36/7206	2.1324683219e-05
ko03040	Spliceosome	1/606	145/7206	5.99271286328e-05
ko04972	Pancreatic secretion	22/606	111/7206	0.000166093545763
ko04730	Long-term depression	17/606	78/7206	0.000202734142209
ko05414	Dilated cardiomyopathy	21/606	112/7206	0.000406434635153
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	16/606	79/7206	0.000736867256368
ko05168	Herpes simplex infection	4/606	182/7206	0.000962911681452
ko04540	Gap junction	22/606	128/7206	0.00105876813269
ko04971	Gastric acid secretion	18/606	98/7206	0.00135767949635
ko04070	Phosphatidylinositol signaling system	20/606	112/7206	0.00150031537982
ko05169	Epstein-Barr virus infection	6/606	206/7206	0.00201264512133
ko04915	Estrogen signaling pathway	22/606	131/7206	0.00203412521274
ko04110	Cell cycle	3/606	145/7206	0.00226403678918
ko04022	cGMP-PKG signaling pathway	31/606	216/7206	0.00267662928908
ko04141	Protein processing in endoplasmic reticulum	5/606	184/7206	0.00272071640711
ko04740	Olfactory transduction	15/606	80/7206	0.00325813604045
ko04514	Cell adhesion molecules (CAMs)	21/606	130/7206	0.00345741152519
ko04750	Inflammatory mediator regulation of TRP channels	20/606	122/7206	0.00428192221943
ko05231	Choline metabolism in cancer	21/606	134/7206	0.00440966450252
ko05014	Amyotrophic lateral sclerosis (ALS)	14/606	74/7206	0.00449578578736
ko04621	NOD-like receptor signaling pathway	4/606	157/7206	0.00506454805435
ko04923	Regulation of lipolysis in adipocytes	14/606	77/7206	0.00554972785795
ko05110	Vibrio cholerae infection	12/606	63/7206	0.00556172577723
ko04630	Jak-STAT signaling pathway	3/606	132/7206	0.00640250294662
ko05322	Systemic lupus erythematosus	4/606	151/7206	0.00689162155795
ko05205	Proteoglycans in cancer	11/606	271/7206	0.00698403390992
ko00240	Pyrimidine metabolism	2/606	110/7206	0.00818279774202
ko03018	RNA degradation	1/606	84/7206	0.00918511976406
ko04932	Non-alcoholic fatty liver disease (NAFLD)	6/606	182/7206	0.00941631311264
ko04550	Signaling pathways regulating pluripotency of stem cells	5/606	165/7206	0.00972286766125
ko04530	Tight junction	9/606	228/7206	0.0104902410055
ko04218	Cellular senescence	6/606	177/7206	0.0126714193034
ko05131	Shigellosis	1/606	82/7206	0.014020822737
ko00515	Mannose type O-glycan biosynthesis	6/606	25/7206	0.0153026166494
ko04966	Collecting duct acid secretion	6/606	26/7206	0.0185186214046
ko00562	Inositol phosphate metabolism	14/606	89/7206	0.0194366385884
ko04140	Autophagy - animal	6/606	164/7206	0.0222655664021
ko05164	Influenza A	6/606	167/7206	0.0226927346938
ko05034	Alcoholism	30/606	238/7206	0.0233803627582
ko05215	Prostate cancer	3/606	111/7206	0.0240263880782
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/606	14/7206	0.0250735898487
ko05410	Hypertrophic cardiomyopathy (HCM)	15/606	100/7206	0.0269544510658
ko00512	Mucin type O-glycan biosynthesis	6/606	29/7206	0.0308501942836
ko05145	Toxoplasmosis	4/606	126/7206	0.0333183905988
ko05200	Pathways in cancer	29/606	492/7206	0.0353949461239
ko05418	Fluid shear stress and atherosclerosis	7/606	173/7206	0.0363622168753
ko00290	Valine, leucine and isoleucine biosynthesis	2/606	4/7206	0.037781514389
ko04640	Hematopoietic cell lineage	1/606	64/7206	0.0410853342938
ko04120	Ubiquitin mediated proteolysis	5/606	138/7206	0.0423896952975
ko04260	Cardiac muscle contraction	14/606	98/7206	0.042753822246
ko05162	Measles	4/606	120/7206	0.0447021712987
ko05016	Huntington's disease	10/606	215/7206	0.0450248352788
ko04014	Ras signaling pathway	33/606	279/7206	0.0465806872977
ko03013	RNA transport	7/606	166/7206	0.0472200027183
ko04068	FoxO signaling pathway	7/606	167/7206	0.0473187523151