ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	180/1292	423/7206	4.11769452784e-34
ko04724	Glutamatergic synapse	76/1292	152/7206	8.4055499866e-20
ko05033	Nicotine addiction	40/1292	56/7206	1.76159797764e-18
ko04727	GABAergic synapse	56/1292	110/7206	2.39888918048e-15
ko05032	Morphine addiction	56/1292	110/7206	2.39888918048e-15
ko04020	Calcium signaling pathway	100/1292	265/7206	9.71514125242e-15
ko04721	Synaptic vesicle cycle	45/1292	80/7206	1.13802199515e-14
ko04713	Circadian entrainment	61/1292	136/7206	2.23081338371e-13
ko04024	cAMP signaling pathway	97/1292	279/7206	8.08697398146e-12
ko04728	Dopaminergic synapse	72/1292	185/7206	8.94800966534e-12
ko04725	Cholinergic synapse	65/1292	160/7206	9.5698152614e-12
ko04726	Serotonergic synapse	56/1292	137/7206	2.3572205636e-10
ko03010	Ribosome	1/1292	129/7206	3.38050028518e-10
ko04911	Insulin secretion	49/1292	117/7206	1.0706938293e-09
ko04921	Oxytocin signaling pathway	74/1292	209/7206	1.11041925378e-09
ko04723	Retrograde endocannabinoid signaling	65/1292	175/7206	1.36482907162e-09
ko03040	Spliceosome	3/1292	145/7206	2.40404236765e-09
ko04742	Taste transduction	31/1292	61/7206	4.67561230967e-09
ko04744	Phototransduction	22/1292	36/7206	9.32564355882e-09
ko03013	RNA transport	6/1292	166/7206	2.77200750139e-08
ko05322	Systemic lupus erythematosus	5/1292	151/7206	6.94081398702e-08
ko04110	Cell cycle	5/1292	145/7206	1.44807098036e-07
ko04022	cGMP-PKG signaling pathway	70/1292	216/7206	1.83651404871e-07
ko04261	Adrenergic signaling in cardiomyocytes	67/1292	205/7206	2.40360565e-07
ko05203	Viral carcinogenesis	20/1292	277/7206	2.44196348437e-07
ko05031	Amphetamine addiction	37/1292	91/7206	2.93983986236e-07
ko04970	Salivary secretion	38/1292	95/7206	4.55987003139e-07
ko03008	Ribosome biogenesis in eukaryotes	1/1292	79/7206	4.76120598698e-06
ko04966	Collecting duct acid secretion	15/1292	26/7206	6.24906021206e-06
ko04720	Long-term potentiation	36/1292	99/7206	1.44079501439e-05
ko04971	Gastric acid secretion	35/1292	98/7206	2.51739589508e-05
ko04925	Aldosterone synthesis and secretion	37/1292	105/7206	2.6977646053e-05
ko04070	Phosphatidylinositol signaling system	38/1292	112/7206	5.01023081935e-05
ko04141	Protein processing in endoplasmic reticulum	14/1292	184/7206	8.3444775032e-05
ko04072	Phospholipase D signaling pathway	57/1292	197/7206	0.000142375947757
ko04730	Long-term depression	28/1292	78/7206	0.000143804447133
ko04922	Glucagon signaling pathway	40/1292	128/7206	0.000255931171183
ko05030	Cocaine addiction	26/1292	73/7206	0.000300921281067
ko04924	Renin secretion	29/1292	86/7206	0.000349515501001
ko04972	Pancreatic secretion	35/1292	111/7206	0.000419918247445
ko04745	Phototransduction - fly	16/1292	38/7206	0.000434864210992
ko03050	Proteasome	1/1292	54/7206	0.000510726183667
ko04514	Cell adhesion molecules (CAMs)	39/1292	130/7206	0.000715884186364
ko04964	Proximal tubule bicarbonate reclamation	13/1292	29/7206	0.000729212867534
ko04010	MAPK signaling pathway	81/1292	321/7206	0.000779967903287
ko04710	Circadian rhythm	17/1292	43/7206	0.000897792471188
ko00120	Primary bile acid biosynthesis	10/1292	20/7206	0.00106794869252
ko05168	Herpes simplex infection	17/1292	182/7206	0.00161178125226
ko04350	TGF-beta signaling pathway	7/1292	103/7206	0.00170838208137
ko03420	Nucleotide excision repair	1/1292	46/7206	0.00178498520468
ko05016	Huntington's disease	22/1292	215/7206	0.0020504919736
ko05169	Epstein-Barr virus infection	21/1292	206/7206	0.00228689002518
ko04014	Ras signaling pathway	70/1292	279/7206	0.00238706785848
ko00520	Amino sugar and nucleotide sugar metabolism	2/1292	55/7206	0.00242134387659
ko03022	Basal transcription factors	1/1292	44/7206	0.00269129519148
ko05110	Vibrio cholerae infection	21/1292	63/7206	0.00272511187288
ko04750	Inflammatory mediator regulation of TRP channels	35/1292	122/7206	0.00283703007385
ko04371	Apelin signaling pathway	47/1292	177/7206	0.00383870648362
ko04270	Vascular smooth muscle contraction	42/1292	154/7206	0.00388965369128
ko04623	Cytosolic DNA-sensing pathway	1/1292	41/7206	0.00645600590564
ko05130	Pathogenic Escherichia coli infection	5/1292	77/7206	0.00652321302228
ko04540	Gap junction	35/1292	128/7206	0.00727092344235
ko04976	Bile secretion	24/1292	80/7206	0.0077329153362
ko04626	Plant-pathogen interaction	8/1292	18/7206	0.00833719821575
ko03410	Base excision repair	1/1292	38/7206	0.00940707507026
ko05205	Proteoglycans in cancer	33/1292	271/7206	0.0120714589306
ko04960	Aldosterone-regulated sodium reabsorption	14/1292	41/7206	0.012385898284
ko04214	Apoptosis - fly	5/1292	72/7206	0.0125919631014
ko04120	Ubiquitin mediated proteolysis	14/1292	138/7206	0.0135559012213
ko05014	Amyotrophic lateral sclerosis (ALS)	22/1292	74/7206	0.0136400722675
ko04210	Apoptosis	20/1292	180/7206	0.0137563493947
ko05161	Hepatitis B	19/1292	173/7206	0.0156247624921
ko00562	Inositol phosphate metabolism	25/1292	89/7206	0.0172646439523
ko04113	Meiosis - yeast	5/1292	70/7206	0.0175937190537
ko04550	Signaling pathways regulating pluripotency of stem cells	18/1292	165/7206	0.0176989653675
ko04740	Olfactory transduction	23/1292	80/7206	0.0178560070083
ko04711	Circadian rhythm - fly	6/1292	13/7206	0.0179051395372
ko05200	Pathways in cancer	69/1292	492/7206	0.0205139144323
ko00860	Porphyrin and chlorophyll metabolism	1/1292	34/7206	0.0219289511177
ko04923	Regulation of lipolysis in adipocytes	22/1292	77/7206	0.0236141155161
ko05215	Prostate cancer	11/1292	111/7206	0.0244840495155
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1292	14/7206	0.0266724442537
ko04930	Type II diabetes mellitus	16/1292	54/7206	0.0316996059183
ko04260	Cardiac muscle contraction	26/1292	98/7206	0.0329678623132
ko04657	IL-17 signaling pathway	8/1292	87/7206	0.0339225452536
ko05414	Dilated cardiomyopathy	29/1292	112/7206	0.0340256659176
ko05323	Rheumatoid arthritis	24/1292	89/7206	0.0356483902346
ko05219	Bladder cancer	3/1292	48/7206	0.0358893788264
ko05206	MicroRNAs in cancer	21/1292	177/7206	0.036581345521
ko03015	mRNA surveillance pathway	9/1292	93/7206	0.0401458714283
ko05164	Influenza A	20/1292	167/7206	0.0412796301718
ko03018	RNA degradation	8/1292	84/7206	0.0445312893345
ko05224	Breast cancer	21/1292	174/7206	0.0448360647862
ko05220	Chronic myeloid leukemia	8/1292	85/7206	0.045038907908
ko00010	Glycolysis / Gluconeogenesis	20/1292	74/7206	0.0472045140043
ko05140	Leishmaniasis	7/1292	75/7206	0.0495488447176