ko pathway ratio_in_study ratio_in_pop p_value ko04064 NF-kappa B signaling pathway 20/202 96/7206 1.1721021969e-12 ko04650 Natural killer cell mediated cytotoxicity 20/202 97/7206 1.44073536056e-12 ko04380 Osteoclast differentiation 23/202 134/7206 1.64385701946e-12 ko04060 Cytokine-cytokine receptor interaction 26/202 191/7206 1.34844903772e-11 ko05340 Primary immunodeficiency 11/202 30/7206 2.19491196185e-10 ko04621 NOD-like receptor signaling pathway 22/202 157/7206 3.20351748532e-10 ko04660 T cell receptor signaling pathway 19/202 124/7206 1.18781137129e-09 ko05140 Leishmaniasis 15/202 75/7206 1.60000041126e-09 ko05152 Tuberculosis 23/202 187/7206 1.73537228152e-09 ko05162 Measles 18/202 120/7206 4.71682050742e-09 ko05168 Herpes simplex infection 22/202 182/7206 5.58431033789e-09 ko05330 Allograft rejection 9/202 24/7206 8.12849611867e-09 ko04620 Toll-like receptor signaling pathway 16/202 100/7206 1.35917672407e-08 ko04662 B cell receptor signaling pathway 15/202 88/7206 1.61478045974e-08 ko05150 Staphylococcus aureus infection 10/202 36/7206 3.22979166701e-08 ko05164 Influenza A 19/202 167/7206 1.73639170479e-07 ko05144 Malaria 10/202 45/7206 3.25185571003e-07 ko05145 Toxoplasmosis 16/202 126/7206 3.79066194086e-07 ko04630 Jak-STAT signaling pathway 16/202 132/7206 7.21089664136e-07 ko05320 Autoimmune thyroid disease 8/202 29/7206 8.58883229353e-07 ko04622 RIG-I-like receptor signaling pathway 11/202 62/7206 9.29918055709e-07 ko05161 Hepatitis B 18/202 173/7206 1.41112502284e-06 ko05321 Inflammatory bowel disease (IBD) 10/202 56/7206 2.77337593833e-06 ko05332 Graft-versus-host disease 6/202 18/7206 6.31236700033e-06 ko04659 Th17 cell differentiation 13/202 106/7206 7.20583878112e-06 ko04664 Fc epsilon RI signaling pathway 11/202 77/7206 8.46026467451e-06 ko05142 Chagas disease (American trypanosomiasis) 14/202 130/7206 1.47110180495e-05 ko04940 Type I diabetes mellitus 7/202 32/7206 2.27385925715e-05 ko05167 Kaposi's sarcoma-associated herpesvirus infection 17/202 191/7206 2.28971487553e-05 ko05133 Pertussis 11/202 87/7206 2.77522461489e-05 ko04668 TNF signaling pathway 13/202 120/7206 2.80884913952e-05 ko04666 Fc gamma R-mediated phagocytosis 13/202 122/7206 3.35295849198e-05 ko04217 Necroptosis 16/202 178/7206 3.55662943203e-05 ko04210 Apoptosis 16/202 180/7206 4.07994668686e-05 ko04672 Intestinal immune network for IgA production 7/202 37/7206 6.174995967e-05 ko05310 Asthma 5/202 17/7206 7.74399891453e-05 ko04623 Cytosolic DNA-sensing pathway 7/202 41/7206 0.000122614689379 ko04612 Antigen processing and presentation 9/202 77/7206 0.00027696094018 ko04658 Th1 and Th2 cell differentiation 10/202 96/7206 0.000331397821568 ko05169 Epstein-Barr virus infection 15/202 206/7206 0.000638750479283 ko04610 Complement and coagulation cascades 8/202 79/7206 0.00157204045069 ko05143 African trypanosomiasis 5/202 32/7206 0.00179006997092 ko04145 Phagosome 12/202 162/7206 0.00191471431855 ko05131 Shigellosis 8/202 82/7206 0.00199948233869 ko04611 Platelet activation 12/202 163/7206 0.00201701641027 ko05160 Hepatitis C 11/202 153/7206 0.00369453081636 ko04062 Chemokine signaling pathway 13/202 201/7206 0.00414401093135 ko05166 HTLV-I infection 17/202 292/7206 0.00536036275077 ko04640 Hematopoietic cell lineage 6/202 64/7206 0.00874604840213 ko04670 Leukocyte transendothelial migration 10/202 151/7206 0.00973875879821 ko05323 Rheumatoid arthritis 7/202 89/7206 0.0121425029512 ko05134 Legionellosis 6/202 74/7206 0.0171834909209 ko05416 Viral myocarditis 5/202 55/7206 0.0184247928606 ko05146 Amoebiasis 7/202 99/7206 0.0207930265985 ko05020 Prion diseases 4/202 40/7206 0.0249244441474 ko05016 Huntington's disease 1/202 215/7206 0.0323999590099 ko04657 IL-17 signaling pathway 6/202 87/7206 0.0348421158139 ko00511 Other glycan degradation 3/202 26/7206 0.0351272054034 ko04020 Calcium signaling pathway 2/202 265/7206 0.0352192107085 ko04142 Lysosome 9/202 151/7206 0.0388107384298 ko00601 Glycosphingolipid biosynthesis - lacto and neolacto series 3/202 28/7206 0.0425034865946