ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04060	Cytokine-cytokine receptor interaction	45/509	191/7206	2.1440328768e-13
ko04070	Phosphatidylinositol signaling system	23/509	112/7206	2.50638244816e-06
ko04072	Phospholipase D signaling pathway	33/509	197/7206	2.7767048213e-06
ko04710	Circadian rhythm	13/509	43/7206	4.77766250317e-06
ko04020	Calcium signaling pathway	39/509	265/7206	1.20767543875e-05
ko05230	Central carbon metabolism in cancer	16/509	81/7206	0.00013827417304
ko04014	Ras signaling pathway	37/509	279/7206	0.0001762915298
ko04064	NF-kappa B signaling pathway	17/509	96/7206	0.000344684836394
ko04630	Jak-STAT signaling pathway	21/509	132/7206	0.000398486370468
ko05321	Inflammatory bowel disease (IBD)	12/509	56/7206	0.000429147805182
ko04380	Osteoclast differentiation	21/509	134/7206	0.000469918249847
ko05231	Choline metabolism in cancer	21/509	134/7206	0.000469918249847
ko04725	Cholinergic synapse	23/509	160/7206	0.000896628973767
ko04650	Natural killer cell mediated cytotoxicity	16/509	97/7206	0.0011398150364
ko04662	B cell receptor signaling pathway	15/509	88/7206	0.00114242010799
ko04711	Circadian rhythm - fly	5/509	13/7206	0.00137793080977
ko04015	Rap1 signaling pathway	34/509	278/7206	0.00168167946893
ko04933	AGE-RAGE signaling pathway in diabetic complications	20/509	135/7206	0.00171200857788
ko05322	Systemic lupus erythematosus	2/509	151/7206	0.00198919372372
ko04921	Oxytocin signaling pathway	27/509	209/7206	0.00221544328208
ko00590	Arachidonic acid metabolism	10/509	52/7206	0.00301169083014
ko05160	Hepatitis C	21/509	153/7206	0.00339095522549
ko04621	NOD-like receptor signaling pathway	21/509	157/7206	0.00405985996226
ko00562	Inositol phosphate metabolism	14/509	89/7206	0.00499708324596
ko04668	TNF signaling pathway	17/509	120/7206	0.00578810534737
ko05162	Measles	17/509	120/7206	0.00578810534737
ko05167	Kaposi's sarcoma-associated herpesvirus infection	24/509	191/7206	0.00581658232211
ko04666	Fc gamma R-mediated phagocytosis	17/509	122/7206	0.0064131365742
ko04611	Platelet activation	21/509	163/7206	0.00754155614882
ko05200	Pathways in cancer	50/509	492/7206	0.00795892431312
ko04925	Aldosterone synthesis and secretion	15/509	105/7206	0.0105409178694
ko04659	Th17 cell differentiation	15/509	106/7206	0.0108974245474
ko04610	Complement and coagulation cascades	12/509	79/7206	0.0119164625094
ko05214	Glioma	12/509	79/7206	0.0119164625094
ko04672	Intestinal immune network for IgA production	7/509	37/7206	0.0135357167106
ko05215	Prostate cancer	15/509	111/7206	0.0135945124319
ko04022	cGMP-PKG signaling pathway	25/509	216/7206	0.014255729179
ko04120	Ubiquitin mediated proteolysis	3/509	138/7206	0.0179480009361
ko04750	Inflammatory mediator regulation of TRP channels	16/509	122/7206	0.0181981565938
ko04010	MAPK signaling pathway	34/509	321/7206	0.0184777955416
ko04066	HIF-1 signaling pathway	16/509	123/7206	0.0187083542011
ko05152	Tuberculosis	22/509	187/7206	0.0192268062111
ko01521	EGFR tyrosine kinase inhibitor resistance	14/509	106/7206	0.0202205742188
ko04960	Aldosterone-regulated sodium reabsorption	7/509	41/7206	0.0231880478835
ko04080	Neuroactive ligand-receptor interaction	42/509	423/7206	0.0238763347628
ko05223	Non-small cell lung cancer	10/509	66/7206	0.0243546650004
ko04726	Serotonergic synapse	17/509	137/7206	0.0262615181062
ko00471	D-Glutamine and D-glutamate metabolism	2/509	4/7206	0.0271515145549
ko05146	Amoebiasis	13/509	99/7206	0.0272087030324
ko04620	Toll-like receptor signaling pathway	13/509	100/7206	0.0285174649815
ko04919	Thyroid hormone signaling pathway	17/509	143/7206	0.0307809727177
ko01200	Carbon metabolism	3/509	128/7206	0.0346476870821
ko04062	Chemokine signaling pathway	22/509	201/7206	0.0356269405031
ko04270	Vascular smooth muscle contraction	18/509	154/7206	0.0363956162621
ko04217	Necroptosis	20/509	178/7206	0.0366472093158
ko00600	Sphingolipid metabolism	9/509	63/7206	0.0413985090657
ko04931	Insulin resistance	16/509	137/7206	0.0418973005421
ko04640	Hematopoietic cell lineage	9/509	64/7206	0.0436851266729
ko04658	Th1 and Th2 cell differentiation	12/509	96/7206	0.0441083999792
ko05164	Influenza A	19/509	167/7206	0.0446488071799
ko04110	Cell cycle	4/509	145/7206	0.0468285715659
ko00120	Primary bile acid biosynthesis	4/509	20/7206	0.0482230074405
ko05161	Hepatitis B	19/509	173/7206	0.0497358153924