ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	26/407	56/7206	2.25620405084e-18
ko04724	Glutamatergic synapse	39/407	152/7206	2.99648251816e-16
ko04728	Dopaminergic synapse	42/407	185/7206	2.32972682462e-15
ko04727	GABAergic synapse	31/407	110/7206	2.33913944011e-14
ko04080	Neuroactive ligand-receptor interaction	65/407	423/7206	3.22141448297e-14
ko04721	Synaptic vesicle cycle	26/407	80/7206	7.38986869701e-14
ko04723	Retrograde endocannabinoid signaling	35/407	175/7206	2.75437077367e-11
ko05032	Morphine addiction	25/407	110/7206	1.28076231989e-09
ko05030	Cocaine addiction	19/407	73/7206	1.19913231677e-08
ko04713	Circadian entrainment	26/407	136/7206	2.87862434305e-08
ko04514	Cell adhesion molecules (CAMs)	25/407	130/7206	4.73639805961e-08
ko04725	Cholinergic synapse	26/407	160/7206	8.34538065534e-07
ko04010	MAPK signaling pathway	40/407	321/7206	1.5813274467e-06
ko04911	Insulin secretion	21/407	117/7206	1.87833739829e-06
ko04726	Serotonergic synapse	23/407	137/7206	2.03763201867e-06
ko05031	Amphetamine addiction	18/407	91/7206	2.43220658973e-06
ko04024	cAMP signaling pathway	35/407	279/7206	7.13603414408e-06
ko05203	Viral carcinogenesis	2/407	277/7206	2.52449919547e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	14/407	74/7206	5.42936020604e-05
ko04261	Adrenergic signaling in cardiomyocytes	24/407	205/7206	0.000583550426975
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	12/407	79/7206	0.00145945772987
ko04742	Taste transduction	10/407	61/7206	0.00199409672929
ko04060	Cytokine-cytokine receptor interaction	2/407	191/7206	0.00212156680878
ko05205	Proteoglycans in cancer	5/407	271/7206	0.00290435214767
ko03040	Spliceosome	1/407	145/7206	0.00325083441819
ko04360	Axon guidance	24/407	233/7206	0.00363858959521
ko04730	Long-term depression	11/407	78/7206	0.00412651427105
ko05164	Influenza A	2/407	167/7206	0.00607343748949
ko02024	Quorum sensing	4/407	15/7206	0.00831785476163
ko04611	Platelet activation	2/407	163/7206	0.00883092208896
ko04140	Autophagy - animal	2/407	164/7206	0.00894743361791
ko04260	Cardiac muscle contraction	12/407	98/7206	0.0120397986448
ko04217	Necroptosis	3/407	178/7206	0.0133601221404
ko05169	Epstein-Barr virus infection	4/407	206/7206	0.0137537859112
ko04150	mTOR signaling pathway	3/407	184/7206	0.0137794401237
ko04211	Longevity regulating pathway	1/407	123/7206	0.0154824891855
ko04110	Cell cycle	2/407	145/7206	0.0172622052732
ko00240	Pyrimidine metabolism	1/407	110/7206	0.0209892299575
ko04070	Phosphatidylinositol signaling system	1/407	112/7206	0.0211859580454
ko04120	Ubiquitin mediated proteolysis	2/407	138/7206	0.0243313056341
ko03013	RNA transport	3/407	166/7206	0.0256676178566
ko00230	Purine metabolism	4/407	194/7206	0.0258003304089
ko04720	Long-term potentiation	11/407	99/7206	0.0263310921429
ko05166	HTLV-I infection	8/407	292/7206	0.0268010880756
ko05410	Hypertrophic cardiomyopathy (HCM)	11/407	100/7206	0.0277623569453
ko04930	Type II diabetes mellitus	7/407	54/7206	0.0310793327492
ko04940	Type I diabetes mellitus	5/407	32/7206	0.0320045218082
ko04014	Ras signaling pathway	24/407	279/7206	0.0341782704701
ko04141	Protein processing in endoplasmic reticulum	4/407	184/7206	0.0346037801797
ko04621	NOD-like receptor signaling pathway	3/407	157/7206	0.035157831621
ko00604	Glycosphingolipid biosynthesis - ganglio series	3/407	14/7206	0.0408803519717
ko00430	Taurine and hypotaurine metabolism	3/407	14/7206	0.0408803519717
ko04921	Oxytocin signaling pathway	19/407	209/7206	0.0456904531207
ko05168	Herpes simplex infection	4/407	182/7206	0.0482312140499
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/407	182/7206	0.0482312140499
ko01200	Carbon metabolism	2/407	128/7206	0.0495161512385