ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	75/835	152/7206	2.02573424053e-31
ko05033	Nicotine addiction	43/835	56/7206	9.0969076906e-30
ko04080	Neuroactive ligand-receptor interaction	132/835	423/7206	2.99341981955e-29
ko04727	GABAergic synapse	56/835	110/7206	1.51594286257e-24
ko05032	Morphine addiction	55/835	110/7206	1.25632011132e-23
ko04713	Circadian entrainment	58/835	136/7206	1.681484791e-20
ko04728	Dopaminergic synapse	69/835	185/7206	3.03594571753e-20
ko04744	Phototransduction	28/835	36/7206	4.98269534743e-20
ko04723	Retrograde endocannabinoid signaling	66/835	175/7206	1.04865403233e-19
ko04725	Cholinergic synapse	55/835	160/7206	1.45184053004e-14
ko04721	Synaptic vesicle cycle	36/835	80/7206	4.72069897381e-14
ko04742	Taste transduction	30/835	61/7206	3.44180848717e-13
ko04726	Serotonergic synapse	47/835	137/7206	1.38752361218e-12
ko04740	Olfactory transduction	34/835	80/7206	1.82901532817e-12
ko04024	cAMP signaling pathway	72/835	279/7206	2.07788374917e-11
ko04911	Insulin secretion	39/835	117/7206	3.12180268055e-10
ko04020	Calcium signaling pathway	65/835	265/7206	1.81286231791e-09
ko05031	Amphetamine addiction	32/835	91/7206	2.7589818856e-09
ko04921	Oxytocin signaling pathway	54/835	209/7206	7.54849375059e-09
ko04261	Adrenergic signaling in cardiomyocytes	52/835	205/7206	2.4458354454e-08
ko04970	Salivary secretion	30/835	95/7206	1.40923400464e-07
ko05203	Viral carcinogenesis	8/835	277/7206	1.50087045194e-07
ko05030	Cocaine addiction	25/835	73/7206	2.73749284343e-07
ko04720	Long-term potentiation	30/835	99/7206	3.87925715891e-07
ko03040	Spliceosome	1/835	145/7206	5.46097904113e-07
ko04010	MAPK signaling pathway	64/835	321/7206	9.84697591436e-06
ko04730	Long-term depression	23/835	78/7206	1.4545224784e-05
ko05164	Influenza A	4/835	167/7206	2.22051300751e-05
ko04514	Cell adhesion molecules (CAMs)	32/835	130/7206	2.39047083568e-05
ko04022	cGMP-PKG signaling pathway	46/835	216/7206	3.21209732879e-05
ko04260	Cardiac muscle contraction	26/835	98/7206	3.7859950625e-05
ko04925	Aldosterone synthesis and secretion	27/835	105/7206	4.44391980976e-05
ko04060	Cytokine-cytokine receptor interaction	6/835	191/7206	4.55945377721e-05
ko04120	Ubiquitin mediated proteolysis	3/835	138/7206	7.37273441021e-05
ko05162	Measles	2/835	120/7206	7.71847295735e-05
ko05322	Systemic lupus erythematosus	4/835	151/7206	9.31440382152e-05
ko04621	NOD-like receptor signaling pathway	5/835	157/7206	0.000220105745249
ko04924	Renin secretion	22/835	86/7206	0.000254101339716
ko05014	Amyotrophic lateral sclerosis (ALS)	20/835	74/7206	0.000302772611032
ko04971	Gastric acid secretion	24/835	98/7206	0.000324225937276
ko05168	Herpes simplex infection	7/835	182/7206	0.00036393124148
ko05169	Epstein-Barr virus infection	9/835	206/7206	0.000369620343987
ko04972	Pancreatic secretion	26/835	111/7206	0.000430335618911
ko03013	RNA transport	6/835	166/7206	0.000490877022406
ko05166	HTLV-I infection	16/835	292/7206	0.000498370305801
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	20/835	79/7206	0.000563662704863
ko04745	Phototransduction - fly	12/835	38/7206	0.000833525178279
ko05205	Proteoglycans in cancer	15/835	271/7206	0.000917118620188
ko04964	Proximal tubule bicarbonate reclamation	10/835	29/7206	0.00104892043614
ko04072	Phospholipase D signaling pathway	38/835	197/7206	0.00142036377966
ko04141	Protein processing in endoplasmic reticulum	9/835	184/7206	0.00227128623364
ko04110	Cell cycle	6/835	145/7206	0.00239029483807
ko04214	Apoptosis - fly	1/835	72/7206	0.00253413797795
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/835	59/7206	0.00303998959402
ko04932	Non-alcoholic fatty liver disease (NAFLD)	9/835	182/7206	0.00308524841552
ko05215	Prostate cancer	4/835	111/7206	0.00430043508946
ko03018	RNA degradation	2/835	84/7206	0.00511580568257
ko05161	Hepatitis B	9/835	173/7206	0.00541868991966
ko04064	NF-kappa B signaling pathway	3/835	96/7206	0.00565909103494
ko04070	Phosphatidylinositol signaling system	23/835	112/7206	0.00655520241798
ko03008	Ribosome biogenesis in eukaryotes	2/835	79/7206	0.0070902252442
ko04966	Collecting duct acid secretion	8/835	26/7206	0.00727088665381
ko04014	Ras signaling pathway	47/835	279/7206	0.00735197128688
ko04540	Gap junction	25/835	128/7206	0.0076441976912
ko04330	Notch signaling pathway	1/835	62/7206	0.00825178358227
ko04630	Jak-STAT signaling pathway	6/835	132/7206	0.00843412164625
ko04930	Type II diabetes mellitus	13/835	54/7206	0.00865517935342
ko04217	Necroptosis	10/835	178/7206	0.00882008629655
ko04974	Protein digestion and absorption	20/835	96/7206	0.00905594464192
ko04750	Inflammatory mediator regulation of TRP channels	24/835	122/7206	0.00933683239831
ko05140	Leishmaniasis	2/835	75/7206	0.0101308421566
ko05034	Alcoholism	40/835	238/7206	0.0133379451518
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/835	14/7206	0.0168737706281
ko00520	Amino sugar and nucleotide sugar metabolism	1/835	55/7206	0.0178895529625
ko00480	Glutathione metabolism	1/835	55/7206	0.0178895529625
ko04978	Mineral absorption	10/835	40/7206	0.0208161987841
ko00830	Retinol metabolism	10/835	42/7206	0.0247688505422
ko04150	mTOR signaling pathway	12/835	184/7206	0.0264913311241
ko04640	Hematopoietic cell lineage	2/835	64/7206	0.0295223304042
ko04146	Peroxisome	4/835	89/7206	0.0301657475022
ko05016	Huntington's disease	15/835	215/7206	0.0302109823686
ko04371	Apelin signaling pathway	30/835	177/7206	0.0314618512594
ko05145	Toxoplasmosis	7/835	126/7206	0.0338988754973
ko03420	Nucleotide excision repair	1/835	46/7206	0.0379661272373
ko04915	Estrogen signaling pathway	23/835	131/7206	0.0380585699584
ko00564	Glycerophospholipid metabolism	5/835	99/7206	0.0390329455753
ko05220	Chronic myeloid leukemia	4/835	85/7206	0.0412080791111
ko04657	IL-17 signaling pathway	4/835	87/7206	0.0414698900813
ko00310	Lysine degradation	3/835	73/7206	0.0423958695574
ko04115	p53 signaling pathway	3/835	74/7206	0.0427068641433
ko00562	Inositol phosphate metabolism	17/835	89/7206	0.0429696897866
ko04668	TNF signaling pathway	7/835	120/7206	0.0441167141646
ko04360	Axon guidance	37/835	233/7206	0.0471754818455
ko04140	Autophagy - animal	11/835	164/7206	0.0479729353348
ko04960	Aldosterone-regulated sodium reabsorption	9/835	41/7206	0.0480222585135
ko00240	Pyrimidine metabolism	6/835	110/7206	0.049085802466