ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	27/437	56/7206	9.00881681595e-19
ko04724	Glutamatergic synapse	43/437	152/7206	2.15098264859e-18
ko04080	Neuroactive ligand-receptor interaction	73/437	423/7206	5.06101465695e-17
ko04727	GABAergic synapse	34/437	110/7206	4.70859571687e-16
ko04744	Phototransduction	20/437	36/7206	8.79553788651e-16
ko04713	Circadian entrainment	35/437	136/7206	8.54308377047e-14
ko04728	Dopaminergic synapse	40/437	185/7206	6.79969943681e-13
ko05032	Morphine addiction	30/437	110/7206	1.05512213436e-12
ko04723	Retrograde endocannabinoid signaling	37/437	175/7206	1.06039812283e-11
ko04740	Olfactory transduction	24/437	80/7206	2.24923460973e-11
ko04725	Cholinergic synapse	33/437	160/7206	2.9193387241e-10
ko04721	Synaptic vesicle cycle	21/437	80/7206	6.121046738e-09
ko05014	Amyotrophic lateral sclerosis (ALS)	20/437	74/7206	8.18159291814e-09
ko04024	cAMP signaling pathway	42/437	279/7206	2.7211340113e-08
ko04726	Serotonergic synapse	27/437	137/7206	3.542573906e-08
ko04742	Taste transduction	17/437	61/7206	6.69174136565e-08
ko05031	Amphetamine addiction	20/437	91/7206	3.45840382178e-07
ko05030	Cocaine addiction	17/437	73/7206	1.11813563341e-06
ko04911	Insulin secretion	22/437	117/7206	1.550070583e-06
ko04970	Salivary secretion	19/437	95/7206	3.09874382307e-06
ko04261	Adrenergic signaling in cardiomyocytes	29/437	205/7206	1.68140271908e-05
ko04921	Oxytocin signaling pathway	27/437	209/7206	0.000167902058002
ko04730	Long-term depression	14/437	78/7206	0.000210287783702
ko05164	Influenza A	1/437	167/7206	0.000751113944405
ko04720	Long-term potentiation	15/437	99/7206	0.000840174017921
ko04060	Cytokine-cytokine receptor interaction	2/437	191/7206	0.00101353797823
ko05016	Huntington's disease	3/437	215/7206	0.00123633716255
ko04150	mTOR signaling pathway	2/437	184/7206	0.00145158626177
ko05322	Systemic lupus erythematosus	1/437	151/7206	0.00152519449385
ko04924	Renin secretion	13/437	86/7206	0.00187429848426
ko04260	Cardiac muscle contraction	14/437	98/7206	0.002206271194
ko03040	Spliceosome	1/437	145/7206	0.00224626818178
ko04120	Ubiquitin mediated proteolysis	1/437	138/7206	0.00326061029913
ko05166	HTLV-I infection	7/437	292/7206	0.00539449139837
ko04745	Phototransduction - fly	7/437	38/7206	0.00703993803274
ko04514	Cell adhesion molecules (CAMs)	16/437	130/7206	0.0077411981748
ko04972	Pancreatic secretion	14/437	111/7206	0.00784594509853
ko05034	Alcoholism	25/437	238/7206	0.0078560804138
ko04978	Mineral absorption	7/437	40/7206	0.00937047945171
ko05203	Viral carcinogenesis	7/437	277/7206	0.00956109854143
ko05162	Measles	1/437	120/7206	0.0103227341036
ko04010	MAPK signaling pathway	31/437	321/7206	0.0112819780469
ko05205	Proteoglycans in cancer	7/437	271/7206	0.0128224973676
ko04931	Insulin resistance	2/437	137/7206	0.0172638925285
ko04022	cGMP-PKG signaling pathway	22/437	216/7206	0.0191056106105
ko04062	Chemokine signaling pathway	20/437	201/7206	0.0243817861263
ko04020	Calcium signaling pathway	25/437	265/7206	0.0251025778349
ko04217	Necroptosis	4/437	178/7206	0.0253513256539
ko05168	Herpes simplex infection	4/437	182/7206	0.0258851672807
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/437	182/7206	0.0258851672807
ko04621	NOD-like receptor signaling pathway	3/437	157/7206	0.0259288297362
ko04964	Proximal tubule bicarbonate reclamation	5/437	29/7206	0.0284574082034
ko00564	Glycerophospholipid metabolism	1/437	99/7206	0.0307420097048
ko04110	Cell cycle	3/437	145/7206	0.0349070577151
ko04925	Aldosterone synthesis and secretion	12/437	105/7206	0.0351049961062
ko00830	Retinol metabolism	6/437	42/7206	0.0394443921755
ko04140	Autophagy - animal	4/437	164/7206	0.0463448824746
ko03013	RNA transport	4/437	166/7206	0.046620378171
ko00350	Tyrosine metabolism	5/437	33/7206	0.0467245713903
ko04971	Gastric acid secretion	11/437	98/7206	0.049803105915