ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	33/698	56/7206	6.3064667445e-20
ko04724	Glutamatergic synapse	55/698	152/7206	3.12913433971e-19
ko04080	Neuroactive ligand-receptor interaction	98/698	423/7206	2.42191345313e-17
ko04727	GABAergic synapse	41/698	110/7206	3.86764772994e-15
ko04728	Dopaminergic synapse	54/698	185/7206	2.79989719065e-14
ko04721	Synaptic vesicle cycle	33/698	80/7206	6.58037770898e-14
ko05032	Morphine addiction	39/698	110/7206	1.24065209401e-13
ko04713	Circadian entrainment	43/698	136/7206	6.45271134093e-13
ko04723	Retrograde endocannabinoid signaling	48/698	175/7206	9.89372942069e-12
ko04725	Cholinergic synapse	45/698	160/7206	1.76885029304e-11
ko04360	Axon guidance	51/698	233/7206	1.43449770844e-08
ko04514	Cell adhesion molecules (CAMs)	34/698	130/7206	4.13363721385e-08
ko04024	cAMP signaling pathway	56/698	279/7206	7.64095903841e-08
ko05030	Cocaine addiction	23/698	73/7206	1.76467376792e-07
ko04911	Insulin secretion	29/698	117/7206	1.38771821628e-06
ko04742	Taste transduction	19/698	61/7206	2.52907619384e-06
ko04726	Serotonergic synapse	31/698	137/7206	5.58336661662e-06
ko03040	Spliceosome	1/698	145/7206	1.15174293294e-05
ko05031	Amphetamine addiction	23/698	91/7206	1.20831035442e-05
ko04744	Phototransduction	13/698	36/7206	1.65696975809e-05
ko05203	Viral carcinogenesis	9/698	277/7206	4.52370274242e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	19/698	74/7206	5.43115187179e-05
ko04261	Adrenergic signaling in cardiomyocytes	37/698	205/7206	0.000166769343698
ko04120	Ubiquitin mediated proteolysis	2/698	138/7206	0.000198945033906
ko04950	Maturity onset diabetes of the young	10/698	29/7206	0.000247032052914
ko04010	MAPK signaling pathway	51/698	321/7206	0.000320434849517
ko03013	RNA transport	4/698	166/7206	0.000446656072482
ko04060	Cytokine-cytokine receptor interaction	6/698	191/7206	0.000726553895867
ko04621	NOD-like receptor signaling pathway	4/698	157/7206	0.00088213310675
ko05322	Systemic lupus erythematosus	4/698	151/7206	0.00121739560864
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/698	14/7206	0.00122842686322
ko05164	Influenza A	5/698	167/7206	0.00132423906423
ko05168	Herpes simplex infection	6/698	182/7206	0.00138188323428
ko00240	Pyrimidine metabolism	2/698	110/7206	0.00176890186622
ko04140	Autophagy - animal	5/698	164/7206	0.00186261892982
ko01200	Carbon metabolism	3/698	128/7206	0.00217990758793
ko04391	Hippo signaling pathway - fly	18/698	90/7206	0.00319857105257
ko04141	Protein processing in endoplasmic reticulum	7/698	184/7206	0.00352026790187
ko04740	Olfactory transduction	16/698	80/7206	0.00397175922468
ko04921	Oxytocin signaling pathway	33/698	209/7206	0.00420072062473
ko03018	RNA degradation	1/698	84/7206	0.00431013267008
ko05162	Measles	3/698	120/7206	0.00441106100992
ko04970	Salivary secretion	18/698	95/7206	0.00462794689374
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/698	182/7206	0.00480998869814
ko05169	Epstein-Barr virus infection	9/698	206/7206	0.00580281335355
ko04540	Gap junction	22/698	128/7206	0.00642455774528
ko04064	NF-kappa B signaling pathway	2/698	96/7206	0.00790287283281
ko00310	Lysine degradation	1/698	73/7206	0.00877019014564
ko00010	Glycolysis / Gluconeogenesis	1/698	74/7206	0.0088727393531
ko04730	Long-term depression	15/698	78/7206	0.0103008277731
ko04146	Peroxisome	2/698	89/7206	0.0108140948085
ko04974	Protein digestion and absorption	17/698	96/7206	0.013490561531
ko04720	Long-term potentiation	17/698	99/7206	0.0162111172356
ko04640	Hematopoietic cell lineage	1/698	64/7206	0.0187443134374
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	14/698	79/7206	0.0212822981004
ko04512	ECM-receptor interaction	14/698	79/7206	0.0212822981004
ko04138	Autophagy - yeast	2/698	81/7206	0.02198838189
ko04137	Mitophagy - animal	2/698	82/7206	0.0222541086149
ko00564	Glycerophospholipid metabolism	3/698	99/7206	0.0240150991863
ko04962	Vasopressin-regulated water reabsorption	11/698	58/7206	0.0243202351895
ko04924	Renin secretion	15/698	86/7206	0.0250997454985
ko04961	Endocrine and other factor-regulated calcium reabsorption	11/698	59/7206	0.0267842063436
ko00561	Glycerolipid metabolism	1/698	63/7206	0.0287360147836
ko03008	Ribosome biogenesis in eukaryotes	2/698	79/7206	0.0323416812529
ko04966	Collecting duct acid secretion	6/698	26/7206	0.034544508431
ko05205	Proteoglycans in cancer	16/698	271/7206	0.0354158632868
ko04260	Cardiac muscle contraction	16/698	98/7206	0.0366724025478
ko04214	Apoptosis - fly	2/698	72/7206	0.043890108714
ko04550	Signaling pathways regulating pluripotency of stem cells	24/698	165/7206	0.0442407422957
ko05133	Pertussis	3/698	87/7206	0.0443755790936
ko05140	Leishmaniasis	2/698	75/7206	0.0459310096331
ko04110	Cell cycle	7/698	145/7206	0.0461260142959
ko04910	Insulin signaling pathway	9/698	172/7206	0.0491066324412