ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	19/446	56/7206	3.78083161372e-10
ko04721	Synaptic vesicle cycle	19/446	80/7206	2.56668655575e-07
ko04727	GABAergic synapse	21/446	110/7206	2.87899941767e-06
ko04950	Maturity onset diabetes of the young	10/446	29/7206	5.13836828566e-06
ko04360	Axon guidance	33/446	233/7206	5.88466862342e-06
ko04728	Dopaminergic synapse	26/446	185/7206	7.04459142172e-05
ko05032	Morphine addiction	18/446	110/7206	0.000124531283372
ko04723	Retrograde endocannabinoid signaling	24/446	175/7206	0.000191878970271
ko04550	Signaling pathways regulating pluripotency of stem cells	23/446	165/7206	0.000214501341549
ko04724	Glutamatergic synapse	21/446	152/7206	0.0004621378429
ko04060	Cytokine-cytokine receptor interaction	2/446	191/7206	0.000690675780653
ko04611	Platelet activation	1/446	163/7206	0.000735498757986
ko05014	Amyotrophic lateral sclerosis (ALS)	12/446	74/7206	0.00178314443625
ko04080	Neuroactive ligand-receptor interaction	42/446	423/7206	0.002353961961
ko04911	Insulin secretion	16/446	117/7206	0.00269563046554
ko04514	Cell adhesion molecules (CAMs)	17/446	130/7206	0.00282217480179
ko04391	Hippo signaling pathway - fly	13/446	90/7206	0.00338669214286
ko04120	Ubiquitin mediated proteolysis	1/446	138/7206	0.00341863458831
ko04330	Notch signaling pathway	10/446	62/7206	0.00438241033363
ko04141	Protein processing in endoplasmic reticulum	3/446	184/7206	0.0048556882796
ko05030	Cocaine addiction	11/446	73/7206	0.00490719464078
ko04912	GnRH signaling pathway	1/446	122/7206	0.00686671287245
ko05168	Herpes simplex infection	3/446	182/7206	0.00709624457377
ko04932	Non-alcoholic fatty liver disease (NAFLD)	3/446	182/7206	0.00709624457377
ko03410	Base excision repair	7/446	38/7206	0.00785043435275
ko03040	Spliceosome	2/446	145/7206	0.00849628677653
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/446	14/7206	0.0088101262989
ko04261	Adrenergic signaling in cardiomyocytes	22/446	205/7206	0.0113547755742
ko04725	Cholinergic synapse	18/446	160/7206	0.011993944382
ko04140	Autophagy - animal	3/446	164/7206	0.013205479367
ko03013	RNA transport	3/446	166/7206	0.0133435478996
ko05203	Viral carcinogenesis	8/446	277/7206	0.0154684003619
ko04630	Jak-STAT signaling pathway	2/446	132/7206	0.0170383162334
ko04621	NOD-like receptor signaling pathway	3/446	157/7206	0.0183043212314
ko05322	Systemic lupus erythematosus	3/446	151/7206	0.0253461418926
ko04340	Hedgehog signaling pathway	8/446	58/7206	0.0253655970864
ko05012	Parkinson's disease	3/446	155/7206	0.0262282208396
ko04961	Endocrine and other factor-regulated calcium reabsorption	8/446	59/7206	0.0278200721912
ko04713	Circadian entrainment	15/446	136/7206	0.0285094895708
ko04512	ECM-receptor interaction	10/446	79/7206	0.0293521812049
ko04064	NF-kappa B signaling pathway	1/446	96/7206	0.0303063555192
ko05016	Huntington's disease	6/446	215/7206	0.0308893300582
ko05162	Measles	2/446	120/7206	0.0338932587498
ko04211	Longevity regulating pathway	2/446	123/7206	0.034837104666
ko05133	Pertussis	1/446	87/7206	0.0431779067232
ko04920	Adipocytokine signaling pathway	1/446	89/7206	0.0435356650031
ko04974	Protein digestion and absorption	11/446	96/7206	0.0496556452362