ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	160/983	423/7206	2.95146017366e-38
ko05033	Nicotine addiction	43/983	56/7206	8.9107608001e-27
ko04724	Glutamatergic synapse	74/983	152/7206	7.75517066357e-26
ko04728	Dopaminergic synapse	77/983	185/7206	1.72497235441e-21
ko04721	Synaptic vesicle cycle	46/983	80/7206	2.62656270266e-20
ko05032	Morphine addiction	55/983	110/7206	3.69183603299e-20
ko04727	GABAergic synapse	53/983	110/7206	1.53262009197e-18
ko04713	Circadian entrainment	58/983	136/7206	4.88372720733e-17
ko04725	Cholinergic synapse	63/983	160/7206	2.43211154256e-16
ko04723	Retrograde endocannabinoid signaling	65/983	175/7206	2.40737941039e-15
ko04024	cAMP signaling pathway	87/983	279/7206	9.62708001081e-15
ko04911	Insulin secretion	44/983	117/7206	5.40444150779e-11
ko04020	Calcium signaling pathway	76/983	265/7206	5.84538067661e-11
ko04726	Serotonergic synapse	48/983	137/7206	1.30491457165e-10
ko04261	Adrenergic signaling in cardiomyocytes	63/983	205/7206	1.37090785345e-10
ko04921	Oxytocin signaling pathway	61/983	209/7206	2.26993182103e-09
ko04360	Axon guidance	66/983	233/7206	2.32260452244e-09
ko05031	Amphetamine addiction	35/983	91/7206	2.56394307847e-09
ko04744	Phototransduction	20/983	36/7206	3.47408812185e-09
ko04742	Taste transduction	27/983	61/7206	4.76020836799e-09
ko05203	Viral carcinogenesis	10/983	277/7206	1.86238016944e-08
ko03040	Spliceosome	1/983	145/7206	2.34951641808e-08
ko04970	Salivary secretion	33/983	95/7206	1.32232885716e-07
ko04720	Long-term potentiation	33/983	99/7206	3.98888978096e-07
ko04060	Cytokine-cytokine receptor interaction	6/983	191/7206	1.03110424296e-06
ko04966	Collecting duct acid secretion	14/983	26/7206	1.38003330451e-06
ko05168	Herpes simplex infection	6/983	182/7206	3.0737236899e-06
ko03013	RNA transport	5/983	166/7206	5.32065113229e-06
ko05030	Cocaine addiction	25/983	73/7206	5.87551785858e-06
ko05322	Systemic lupus erythematosus	4/983	151/7206	5.96711293551e-06
ko04514	Cell adhesion molecules (CAMs)	37/983	130/7206	7.15176419453e-06
ko04971	Gastric acid secretion	30/983	98/7206	1.00694793221e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	24/983	74/7206	2.55414146322e-05
ko04120	Ubiquitin mediated proteolysis	4/983	138/7206	2.63075807232e-05
ko04022	cGMP-PKG signaling pathway	52/983	216/7206	2.89513309784e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	25/983	79/7206	3.66267820866e-05
ko04010	MAPK signaling pathway	70/983	321/7206	4.04536859276e-05
ko04070	Phosphatidylinositol signaling system	31/983	112/7206	7.31322633648e-05
ko05164	Influenza A	7/983	167/7206	8.32875972175e-05
ko04925	Aldosterone synthesis and secretion	29/983	105/7206	0.000138849703843
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/983	14/7206	0.000163258801776
ko04141	Protein processing in endoplasmic reticulum	9/983	184/7206	0.000178692679635
ko03008	Ribosome biogenesis in eukaryotes	1/983	79/7206	0.00020233269309
ko04621	NOD-like receptor signaling pathway	7/983	157/7206	0.000225463885475
ko04745	Phototransduction - fly	14/983	38/7206	0.000280604281713
ko04730	Long-term depression	23/983	78/7206	0.000328944390476
ko04972	Pancreatic secretion	29/983	111/7206	0.000395702926545
ko04014	Ras signaling pathway	59/983	279/7206	0.00047446911572
ko04260	Cardiac muscle contraction	26/983	98/7206	0.00056053277417
ko00240	Pyrimidine metabolism	4/983	110/7206	0.000688572866466
ko04064	NF-kappa B signaling pathway	3/983	96/7206	0.000845518657568
ko04740	Olfactory transduction	22/983	80/7206	0.000871729110544
ko05169	Epstein-Barr virus infection	13/983	206/7206	0.000932839362613
ko04924	Renin secretion	23/983	86/7206	0.00123189540416
ko04626	Plant-pathogen interaction	8/983	18/7206	0.00143408932899
ko05205	Proteoglycans in cancer	20/983	271/7206	0.00149853558847
ko04640	Hematopoietic cell lineage	1/983	64/7206	0.00152064227341
ko05140	Leishmaniasis	2/983	75/7206	0.00209407423021
ko04540	Gap junction	30/983	128/7206	0.00249397840224
ko04072	Phospholipase D signaling pathway	42/983	197/7206	0.00297239993005
ko04932	Non-alcoholic fatty liver disease (NAFLD)	12/983	182/7206	0.00306659987398
ko05414	Dilated cardiomyopathy	27/983	112/7206	0.00311183830793
ko05161	Hepatitis B	11/983	173/7206	0.00331376421405
ko04964	Proximal tubule bicarbonate reclamation	10/983	29/7206	0.00365680382186
ko05110	Vibrio cholerae infection	17/983	63/7206	0.0046858114149
ko00480	Glutathione metabolism	1/983	55/7206	0.00503356594072
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/983	59/7206	0.00624576003603
ko04915	Estrogen signaling pathway	29/983	131/7206	0.00668031660158
ko04612	Antigen processing and presentation	3/983	77/7206	0.0072806671813
ko00590	Arachidonic acid metabolism	1/983	52/7206	0.0074813088197
ko04140	Autophagy - animal	11/983	164/7206	0.0076569246677
ko04146	Peroxisome	4/983	89/7206	0.00769535153997
ko01200	Carbon metabolism	8/983	128/7206	0.0127807184579
ko00330	Arginine and proline metabolism	2/983	61/7206	0.0135438417294
ko05120	Epithelial cell signaling in Helicobacter pylori infection	21/983	92/7206	0.0140016280885
ko04110	Cell cycle	10/983	145/7206	0.0141181280817
ko04214	Apoptosis - fly	3/983	72/7206	0.0146367911239
ko00310	Lysine degradation	3/983	73/7206	0.0149255613228
ko03018	RNA degradation	4/983	84/7206	0.0151898040853
ko03420	Nucleotide excision repair	1/983	46/7206	0.0164475836093
ko05219	Bladder cancer	1/983	48/7206	0.01746751629
ko05410	Hypertrophic cardiomyopathy (HCM)	22/983	100/7206	0.0186373575334
ko04668	TNF signaling pathway	8/983	120/7206	0.0220865630041
ko05162	Measles	8/983	120/7206	0.0220865630041
ko04973	Carbohydrate digestion and absorption	11/983	42/7206	0.0241836853119
ko03022	Basal transcription factors	1/983	44/7206	0.0247981923944
ko05144	Malaria	1/983	45/7206	0.0257991337414
ko00071	Fatty acid degradation	1/983	45/7206	0.0257991337414
ko00280	Valine, leucine and isoleucine degradation	2/983	54/7206	0.0277116369726
ko05145	Toxoplasmosis	9/983	126/7206	0.0349355422163
ko00980	Metabolism of xenobiotics by cytochrome P450	1/983	40/7206	0.035892552814
ko00140	Steroid hormone biosynthesis	1/983	41/7206	0.0365963662037
ko04630	Jak-STAT signaling pathway	10/983	132/7206	0.0400556687556
ko04622	RIG-I-like receptor signaling pathway	3/983	62/7206	0.0401802168903
ko00561	Glycerolipid metabolism	3/983	63/7206	0.0405568585331
ko00562	Inositol phosphate metabolism	19/983	89/7206	0.0420447724484
ko05016	Huntington's disease	19/983	215/7206	0.0428284633594
ko04930	Type II diabetes mellitus	13/983	54/7206	0.042875358774
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/983	15/7206	0.0432327785994
ko04391	Hippo signaling pathway - fly	19/983	90/7206	0.0441401505096
ko05166	HTLV-I infection	28/983	292/7206	0.0447066016155
ko04217	Necroptosis	15/983	178/7206	0.0455850160982
ko00512	Mucin type O-glycan biosynthesis	8/983	29/7206	0.0498920094222