ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	86/761	145/7206	8.67474905377e-48
ko03013	RNA transport	70/761	166/7206	1.13314213737e-26
ko04110	Cell cycle	63/761	145/7206	5.98457939698e-25
ko04111	Cell cycle - yeast	46/761	90/7206	3.86525765299e-22
ko03008	Ribosome biogenesis in eukaryotes	40/761	79/7206	3.30971726986e-19
ko03030	DNA replication	26/761	38/7206	2.18653314212e-17
ko04113	Meiosis - yeast	34/761	70/7206	8.51515643739e-16
ko05322	Systemic lupus erythematosus	50/761	151/7206	3.20493672961e-14
ko03440	Homologous recombination	23/761	41/7206	8.13022878593e-13
ko03015	mRNA surveillance pathway	34/761	93/7206	2.02535969907e-11
ko04020	Calcium signaling pathway	2/761	265/7206	7.28212696499e-11
ko00240	Pyrimidine metabolism	36/761	110/7206	2.00751538547e-10
ko03460	Fanconi anemia pathway	22/761	51/7206	1.96163592427e-09
ko03430	Mismatch repair	14/761	22/7206	2.72866246038e-09
ko04060	Cytokine-cytokine receptor interaction	1/761	191/7206	1.51369062315e-08
ko03018	RNA degradation	27/761	84/7206	5.84100462968e-08
ko03420	Nucleotide excision repair	19/761	46/7206	5.92673312946e-08
ko03410	Base excision repair	17/761	38/7206	7.17917767153e-08
ko04024	cAMP signaling pathway	6/761	279/7206	7.76433174741e-08
ko03020	RNA polymerase	14/761	29/7206	3.25182364139e-07
ko05034	Alcoholism	51/761	238/7206	5.19779370983e-07
ko05010	Alzheimer's disease	3/761	202/7206	5.89116361389e-07
ko04725	Cholinergic synapse	1/761	160/7206	6.39902704783e-07
ko05012	Parkinson's disease	1/761	155/7206	9.2051229207e-07
ko04723	Retrograde endocannabinoid signaling	2/761	175/7206	1.17743633798e-06
ko04144	Endocytosis	12/761	342/7206	1.35005175724e-06
ko04921	Oxytocin signaling pathway	4/761	209/7206	1.79779851589e-06
ko04151	PI3K-Akt signaling pathway	16/761	390/7206	3.73446365135e-06
ko04932	Non-alcoholic fatty liver disease (NAFLD)	3/761	182/7206	3.96375389744e-06
ko04022	cGMP-PKG signaling pathway	5/761	216/7206	4.86298461243e-06
ko04726	Serotonergic synapse	1/761	137/7206	7.1424155116e-06
ko04915	Estrogen signaling pathway	1/761	131/7206	1.02888535314e-05
ko00190	Oxidative phosphorylation	1/761	127/7206	1.53994974796e-05
ko04062	Chemokine signaling pathway	5/761	201/7206	2.04942002847e-05
ko04911	Insulin secretion	1/761	117/7206	5.15360495466e-05
ko04270	Vascular smooth muscle contraction	3/761	154/7206	5.50437948269e-05
ko04114	Oocyte meiosis	30/761	139/7206	0.000119375672397
ko04514	Cell adhesion molecules (CAMs)	2/761	130/7206	0.000126121246905
ko05203	Viral carcinogenesis	50/761	277/7206	0.000128778784217
ko04261	Adrenergic signaling in cardiomyocytes	7/761	205/7206	0.00019822879117
ko04015	Rap1 signaling pathway	12/761	278/7206	0.000203579745965
ko04668	TNF signaling pathway	2/761	120/7206	0.000260905452136
ko04014	Ras signaling pathway	13/761	279/7206	0.000466343325448
ko05169	Epstein-Barr virus infection	38/761	206/7206	0.000502097466404
ko05414	Dilated cardiomyopathy	2/761	112/7206	0.000554721998841
ko04371	Apelin signaling pathway	6/761	177/7206	0.000706134639365
ko04360	Axon guidance	10/761	233/7206	0.000707498589065
ko00230	Purine metabolism	36/761	194/7206	0.000780535625282
ko04920	Adipocytokine signaling pathway	1/761	89/7206	0.000821397370874
ko05166	HTLV-I infection	49/761	292/7206	0.000881724496658
ko04621	NOD-like receptor signaling pathway	5/761	157/7206	0.00090924706366
ko04728	Dopaminergic synapse	7/761	185/7206	0.000986525482471
ko04914	Progesterone-mediated oocyte maturation	22/761	104/7206	0.00115957724521
ko04925	Aldosterone synthesis and secretion	2/761	105/7206	0.00116944973526
ko04510	Focal adhesion	11/761	240/7206	0.00122926152635
ko04662	B cell receptor signaling pathway	1/761	88/7206	0.00126413790134
ko04810	Regulation of actin cytoskeleton	13/761	264/7206	0.00144170663399
ko04380	Osteoclast differentiation	4/761	134/7206	0.00163715748192
ko05231	Choline metabolism in cancer	4/761	134/7206	0.00163715748192
ko03060	Protein export	8/761	23/7206	0.00172072971589
ko04611	Platelet activation	6/761	163/7206	0.0018251306538
ko04010	MAPK signaling pathway	18/761	321/7206	0.00206493068197
ko04630	Jak-STAT signaling pathway	4/761	132/7206	0.00233411767119
ko05146	Amoebiasis	2/761	99/7206	0.00251152164979
ko05410	Hypertrophic cardiomyopathy (HCM)	2/761	100/7206	0.00258897340717
ko04721	Synaptic vesicle cycle	1/761	80/7206	0.00272586114086
ko04976	Bile secretion	1/761	80/7206	0.00272586114086
ko03450	Non-homologous end-joining	6/761	15/7206	0.00294364166863
ko04120	Ubiquitin mediated proteolysis	26/761	138/7206	0.00298827668388
ko00670	One carbon pool by folate	7/761	20/7206	0.00321545773249
ko05145	Toxoplasmosis	4/761	126/7206	0.00321651715066
ko00010	Glycolysis / Gluconeogenesis	1/761	74/7206	0.00391092183694
ko04923	Regulation of lipolysis in adipocytes	1/761	77/7206	0.00413120462996
ko04218	Cellular senescence	31/761	177/7206	0.00413280860934
ko04972	Pancreatic secretion	3/761	111/7206	0.00435717021121
ko03022	Basal transcription factors	11/761	44/7206	0.00496136147973
ko04146	Peroxisome	2/761	89/7206	0.00508845006616
ko05031	Amphetamine addiction	2/761	91/7206	0.00518836414636
ko05168	Herpes simplex infection	31/761	182/7206	0.00677390878424
ko04918	Thyroid hormone synthesis	2/761	86/7206	0.00733340490305
ko05152	Tuberculosis	9/761	187/7206	0.00752448737338
ko04620	Toll-like receptor signaling pathway	3/761	100/7206	0.00822937922405
ko04922	Glucagon signaling pathway	5/761	128/7206	0.00877352107761
ko04540	Gap junction	5/761	128/7206	0.00877352107761
ko04072	Phospholipase D signaling pathway	10/761	197/7206	0.00921155178631
ko04658	Th1 and Th2 cell differentiation	3/761	96/7206	0.0115602537027
ko04650	Natural killer cell mediated cytotoxicity	3/761	97/7206	0.0116328767837
ko04070	Phosphatidylinositol signaling system	4/761	112/7206	0.012148771449
ko04640	Hematopoietic cell lineage	1/761	64/7206	0.0125852883972
ko04139	Mitophagy - yeast	9/761	37/7206	0.012797561415
ko04730	Long-term depression	2/761	78/7206	0.0150016729385
ko04931	Insulin resistance	6/761	137/7206	0.0159792058589
ko04912	GnRH signaling pathway	5/761	122/7206	0.0164336714621
ko04750	Inflammatory mediator regulation of TRP channels	5/761	122/7206	0.0164336714621
ko04961	Endocrine and other factor-regulated calcium reabsorption	1/761	59/7206	0.0182369354289
ko04152	AMPK signaling pathway	8/761	161/7206	0.0186337374712
ko05321	Inflammatory bowel disease (IBD)	1/761	56/7206	0.0268719767975
ko04141	Protein processing in endoplasmic reticulum	29/761	184/7206	0.0277441173308
ko04962	Vasopressin-regulated water reabsorption	1/761	58/7206	0.0282311792459
ko05164	Influenza A	9/761	167/7206	0.0291908401606
ko04712	Circadian rhythm - plant	3/761	7/7206	0.0296518504089
ko05167	Kaposi's sarcoma-associated herpesvirus infection	11/761	191/7206	0.0306902830925
ko00564	Glycerophospholipid metabolism	4/761	99/7206	0.0311132958753
ko05200	Pathways in cancer	38/761	492/7206	0.0332260909273
ko04310	Wnt signaling pathway	28/761	181/7206	0.0365361252931
ko04066	HIF-1 signaling pathway	6/761	123/7206	0.037381852539
ko04071	Sphingolipid signaling pathway	9/761	162/7206	0.0374721328211
ko04660	T cell receptor signaling pathway	6/761	124/7206	0.0376435056142
ko00590	Arachidonic acid metabolism	1/761	52/7206	0.0391734904216
ko05202	Transcriptional misregulation in cancer	29/761	188/7206	0.0396858531791
ko04012	ErbB signaling pathway	5/761	109/7206	0.0401006432548
ko04933	AGE-RAGE signaling pathway in diabetic complications	7/761	135/7206	0.0460461982398
ko04530	Tight junction	15/761	228/7206	0.0481694144031