ko pathway ratio_in_study ratio_in_pop p_value ko05340 Primary immunodeficiency 14/217 30/7206 3.15712825462e-14 ko05140 Leishmaniasis 19/217 75/7206 3.68132293393e-13 ko04380 Osteoclast differentiation 24/217 134/7206 9.65486769382e-13 ko05162 Measles 22/217 120/7206 5.55489417689e-12 ko05152 Tuberculosis 26/217 187/7206 4.28763831525e-11 ko04660 T cell receptor signaling pathway 21/217 124/7206 8.34928342666e-11 ko05145 Toxoplasmosis 21/217 126/7206 1.14188260663e-10 ko05164 Influenza A 24/217 167/7206 1.25512296045e-10 ko04621 NOD-like receptor signaling pathway 23/217 157/7206 2.11225827181e-10 ko04064 NF-kappa B signaling pathway 18/217 96/7206 3.51639651244e-10 ko04060 Cytokine-cytokine receptor interaction 25/217 191/7206 3.91599767039e-10 ko04650 Natural killer cell mediated cytotoxicity 18/217 97/7206 4.20393160643e-10 ko04612 Antigen processing and presentation 16/217 77/7206 7.08182028502e-10 ko04620 Toll-like receptor signaling pathway 18/217 100/7206 7.08540781779e-10 ko05168 Herpes simplex infection 24/217 182/7206 7.72404386599e-10 ko05150 Staphylococcus aureus infection 11/217 36/7206 4.44683803589e-09 ko05321 Inflammatory bowel disease (IBD) 13/217 56/7206 7.04184487102e-09 ko04672 Intestinal immune network for IgA production 10/217 37/7206 8.52430494457e-08 ko04659 Th17 cell differentiation 15/217 106/7206 5.36131869013e-07 ko04658 Th1 and Th2 cell differentiation 14/217 96/7206 8.92231280855e-07 ko05161 Hepatitis B 19/217 173/7206 9.23709171964e-07 ko05320 Autoimmune thyroid disease 8/217 29/7206 1.47854877015e-06 ko04630 Jak-STAT signaling pathway 16/217 132/7206 1.87719568485e-06 ko04662 B cell receptor signaling pathway 13/217 88/7206 1.90686522076e-06 ko05330 Allograft rejection 7/217 24/7206 4.55987127802e-06 ko04217 Necroptosis 18/217 178/7206 5.9407406641e-06 ko04145 Phagosome 17/217 162/7206 6.60638670777e-06 ko04062 Chemokine signaling pathway 19/217 201/7206 8.75849063065e-06 ko05167 Kaposi's sarcoma-associated herpesvirus infection 18/217 191/7206 1.58879974001e-05 ko05142 Chagas disease (American trypanosomiasis) 14/217 130/7206 3.29295540711e-05 ko05144 Malaria 8/217 45/7206 4.90031681313e-05 ko05133 Pertussis 11/217 87/7206 5.36985231137e-05 ko05323 Rheumatoid arthritis 11/217 89/7206 6.64225924665e-05 ko04210 Apoptosis 16/217 180/7206 9.65858281965e-05 ko05310 Asthma 5/217 17/7206 0.000108847168821 ko05332 Graft-versus-host disease 5/217 18/7206 0.000147041589028 ko03050 Proteasome 8/217 54/7206 0.000187375969042 ko04622 RIG-I-like receptor signaling pathway 8/217 62/7206 0.000495252660649 ko04514 Cell adhesion molecules (CAMs) 12/217 130/7206 0.000516591326599 ko04610 Complement and coagulation cascades 9/217 79/7206 0.000569094875818 ko05166 HTLV-I infection 20/217 292/7206 0.000587135059898 ko05160 Hepatitis C 13/217 153/7206 0.000676058651913 ko05131 Shigellosis 9/217 82/7206 0.000749543298672 ko04668 TNF signaling pathway 11/217 120/7206 0.000933001499023 ko05416 Viral myocarditis 7/217 55/7206 0.00120980194966 ko04940 Type I diabetes mellitus 5/217 32/7206 0.00245159750375 ko04666 Fc gamma R-mediated phagocytosis 10/217 122/7206 0.00362489389216 ko05169 Epstein-Barr virus infection 14/217 206/7206 0.00529561215711 ko04670 Leukocyte transendothelial migration 11/217 151/7206 0.00572873338788 ko05134 Legionellosis 7/217 74/7206 0.00663144270139 ko04623 Cytosolic DNA-sensing pathway 5/217 41/7206 0.00732970514129 ko04664 Fc epsilon RI signaling pathway 7/217 77/7206 0.00821662832732 ko05132 Salmonella infection 8/217 98/7206 0.00916010412771 ko04640 Hematopoietic cell lineage 6/217 64/7206 0.0121920304491 ko04933 AGE-RAGE signaling pathway in diabetic complications 9/217 135/7206 0.0203872189467 ko00120 Primary bile acid biosynthesis 3/217 20/7206 0.0210347128047 ko05016 Huntington's disease 1/217 215/7206 0.0227562112789 ko04142 Lysosome 10/217 151/7206 0.0249402241136 ko01524 Platinum drug resistance 6/217 76/7206 0.0264645249138 ko05146 Amoebiasis 7/217 99/7206 0.0293244467838 ko04310 Wnt signaling pathway 1/217 181/7206 0.0454012179311 ko04917 Prolactin signaling pathway 6/217 87/7206 0.0467373128364