ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	78/891	152/7206	3.55580720138e-32
ko05033	Nicotine addiction	43/891	56/7206	1.42256667036e-28
ko04727	GABAergic synapse	61/891	110/7206	8.76503725338e-28
ko04080	Neuroactive ligand-receptor interaction	134/891	423/7206	1.79879231862e-27
ko05032	Morphine addiction	59/891	110/7206	7.20850139426e-26
ko04713	Circadian entrainment	63/891	136/7206	5.12972958791e-23
ko04723	Retrograde endocannabinoid signaling	71/891	175/7206	1.24056450731e-21
ko04728	Dopaminergic synapse	70/891	185/7206	2.55698627359e-19
ko04744	Phototransduction	26/891	36/7206	1.33716304926e-16
ko04725	Cholinergic synapse	59/891	160/7206	7.70468097263e-16
ko04721	Synaptic vesicle cycle	37/891	80/7206	5.65663459871e-14
ko04726	Serotonergic synapse	50/891	137/7206	2.11862222746e-13
ko04911	Insulin secretion	44/891	117/7206	1.8333002916e-12
ko04024	cAMP signaling pathway	77/891	279/7206	2.56490085829e-12
ko04921	Oxytocin signaling pathway	63/891	209/7206	4.18400108913e-12
ko04020	Calcium signaling pathway	73/891	265/7206	1.19222122549e-11
ko04742	Taste transduction	28/891	61/7206	8.57386994653e-11
ko05031	Amphetamine addiction	35/891	91/7206	1.70447012121e-10
ko05203	Viral carcinogenesis	7/891	277/7206	4.06252190102e-09
ko04261	Adrenergic signaling in cardiomyocytes	55/891	205/7206	1.55895912603e-08
ko04720	Long-term potentiation	33/891	99/7206	3.72936823262e-08
ko04970	Salivary secretion	32/891	95/7206	4.52820960354e-08
ko05030	Cocaine addiction	27/891	73/7206	5.61314230113e-08
ko04740	Olfactory transduction	28/891	80/7206	1.25552218714e-07
ko04060	Cytokine-cytokine receptor interaction	4/891	191/7206	5.08804926011e-07
ko05164	Influenza A	3/891	167/7206	1.06571227182e-06
ko03040	Spliceosome	2/891	145/7206	1.4303138087e-06
ko04972	Pancreatic secretion	32/891	111/7206	2.77199943341e-06
ko05162	Measles	1/891	120/7206	3.89020011414e-06
ko04925	Aldosterone synthesis and secretion	30/891	105/7206	6.8669688086e-06
ko05322	Systemic lupus erythematosus	3/891	151/7206	7.44558044361e-06
ko05169	Epstein-Barr virus infection	8/891	206/7206	3.57082755602e-05
ko04072	Phospholipase D signaling pathway	45/891	197/7206	3.68365022771e-05
ko04730	Long-term depression	23/891	78/7206	4.1812778314e-05
ko04110	Cell cycle	4/891	145/7206	6.11177582875e-05
ko04070	Phosphatidylinositol signaling system	29/891	112/7206	7.07167105375e-05
ko04010	MAPK signaling pathway	64/891	321/7206	8.26540833533e-05
ko04022	cGMP-PKG signaling pathway	47/891	216/7206	8.44872103155e-05
ko05168	Herpes simplex infection	7/891	182/7206	9.06977434168e-05
ko04745	Phototransduction - fly	14/891	38/7206	9.66904882666e-05
ko04260	Cardiac muscle contraction	26/891	98/7206	0.00013221459365
ko03013	RNA transport	6/891	166/7206	0.000171776476309
ko05205	Proteoglycans in cancer	15/891	271/7206	0.000216334772509
ko04350	TGF-beta signaling pathway	2/891	103/7206	0.000230716655976
ko04141	Protein processing in endoplasmic reticulum	8/891	184/7206	0.000254500064616
ko04964	Proximal tubule bicarbonate reclamation	11/891	29/7206	0.000404524917911
ko04510	Focal adhesion	13/891	240/7206	0.000429135734478
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/891	79/7206	0.000467499921626
ko04550	Signaling pathways regulating pluripotency of stem cells	7/891	165/7206	0.000471333516722
ko04514	Cell adhesion molecules (CAMs)	30/891	130/7206	0.000628577404372
ko05215	Prostate cancer	3/891	111/7206	0.000656032701882
ko04612	Antigen processing and presentation	1/891	77/7206	0.000737226301411
ko03008	Ribosome biogenesis in eukaryotes	1/891	79/7206	0.000782110372506
ko04976	Bile secretion	21/891	80/7206	0.000831410572614
ko04971	Gastric acid secretion	24/891	98/7206	0.000905923104644
ko05161	Hepatitis B	8/891	173/7206	0.00092584655757
ko05166	HTLV-I infection	19/891	292/7206	0.00105102776786
ko04932	Non-alcoholic fatty liver disease (NAFLD)	9/891	182/7206	0.00124451621597
ko04621	NOD-like receptor signaling pathway	7/891	157/7206	0.00125739120177
ko05014	Amyotrophic lateral sclerosis (ALS)	19/891	74/7206	0.00190743817345
ko05224	Breast cancer	9/891	174/7206	0.00221749753381
ko04120	Ubiquitin mediated proteolysis	6/891	138/7206	0.00235911675327
ko04924	Renin secretion	21/891	86/7206	0.00241958209703
ko04966	Collecting duct acid secretion	9/891	26/7206	0.00285335365452
ko00562	Inositol phosphate metabolism	21/891	89/7206	0.00298778833086
ko04630	Jak-STAT signaling pathway	6/891	132/7206	0.00316759394581
ko05414	Dilated cardiomyopathy	25/891	112/7206	0.00328250294782
ko04810	Regulation of actin cytoskeleton	18/891	264/7206	0.00407837787708
ko04540	Gap junction	27/891	128/7206	0.00425749242522
ko05200	Pathways in cancer	41/891	492/7206	0.00442121986024
ko04750	Inflammatory mediator regulation of TRP channels	26/891	122/7206	0.00498594399499
ko05222	Small cell lung cancer	3/891	89/7206	0.005415570695
ko04330	Notch signaling pathway	1/891	62/7206	0.00549459920952
ko05418	Fluid shear stress and atherosclerosis	10/891	173/7206	0.00669002223725
ko00290	Valine, leucine and isoleucine biosynthesis	3/891	4/7206	0.00684214992318
ko05140	Leishmaniasis	2/891	75/7206	0.00702773491007
ko05218	Melanoma	3/891	85/7206	0.00767161606303
ko04218	Cellular senescence	11/891	177/7206	0.0104442298441
ko05131	Shigellosis	3/891	82/7206	0.0108263586241
ko05110	Vibrio cholerae infection	15/891	63/7206	0.010834038393
ko04668	TNF signaling pathway	6/891	120/7206	0.0110651313871
ko04064	NF-kappa B signaling pathway	4/891	96/7206	0.0114556754093
ko05416	Viral myocarditis	1/891	55/7206	0.0118552085751
ko04150	mTOR signaling pathway	12/891	184/7206	0.0122295504932
ko05217	Basal cell carcinoma	2/891	68/7206	0.0144144461621
ko05016	Huntington's disease	15/891	215/7206	0.0149739722578
ko04610	Complement and coagulation cascades	3/891	79/7206	0.0152620414621
ko04014	Ras signaling pathway	48/891	279/7206	0.0156215207291
ko04210	Apoptosis	12/891	180/7206	0.015769891124
ko05034	Alcoholism	42/891	238/7206	0.0158532234205
ko04710	Circadian rhythm	11/891	43/7206	0.016640048178
ko05231	Choline metabolism in cancer	26/891	134/7206	0.0167258074439
ko05145	Toxoplasmosis	7/891	126/7206	0.0191608885889
ko04918	Thyroid hormone synthesis	18/891	86/7206	0.0205710901713
ko04620	Toll-like receptor signaling pathway	5/891	100/7206	0.0209435051962
ko04657	IL-17 signaling pathway	4/891	87/7206	0.0214808657563
ko05133	Pertussis	4/891	87/7206	0.0214808657563
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/891	14/7206	0.0219384388744
ko00910	Nitrogen metabolism	6/891	19/7206	0.0230001493472
ko02010	ABC transporters	10/891	39/7206	0.0232768390612
ko04978	Mineral absorption	10/891	40/7206	0.0259025063807
ko00240	Pyrimidine metabolism	6/891	110/7206	0.0271652335392
ko05211	Renal cell carcinoma	5/891	96/7206	0.0283335348142
ko05220	Chronic myeloid leukemia	4/891	85/7206	0.0297280399366
ko04214	Apoptosis - fly	3/891	72/7206	0.0298854907643
ko05410	Hypertrophic cardiomyopathy (HCM)	20/891	100/7206	0.030391268914
ko04973	Carbohydrate digestion and absorption	10/891	42/7206	0.0327547656213
ko04930	Type II diabetes mellitus	12/891	54/7206	0.0362635567372
ko03022	Basal transcription factors	1/891	44/7206	0.0371654068336
ko04217	Necroptosis	13/891	178/7206	0.0374571203726
ko05144	Malaria	1/891	45/7206	0.0377185995091
ko03420	Nucleotide excision repair	1/891	46/7206	0.0388739198986
ko05321	Inflammatory bowel disease (IBD)	2/891	56/7206	0.0409712177102
ko03320	PPAR signaling pathway	3/891	69/7206	0.0417095580513
ko05212	Pancreatic cancer	4/891	83/7206	0.0417138061914
ko05202	Transcriptional misregulation in cancer	14/891	188/7206	0.0423199275704
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/891	59/7206	0.0433513804781
ko04915	Estrogen signaling pathway	24/891	131/7206	0.0437700842138
ko04520	Adherens junction	6/891	103/7206	0.0481410503704
ko04371	Apelin signaling pathway	31/891	177/7206	0.0481851610245