ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	190/1201	423/7206	2.65896476898e-45
ko04724	Glutamatergic synapse	83/1201	152/7206	3.77842054543e-27
ko05032	Morphine addiction	67/1201	110/7206	7.16511278633e-26
ko05033	Nicotine addiction	45/1201	56/7206	1.07662536209e-25
ko04713	Circadian entrainment	72/1201	136/7206	1.33153517941e-22
ko04727	GABAergic synapse	62/1201	110/7206	1.64631952175e-21
ko04721	Synaptic vesicle cycle	49/1201	80/7206	2.25330527038e-19
ko04020	Calcium signaling pathway	102/1201	265/7206	3.96275227301e-18
ko04725	Cholinergic synapse	73/1201	160/7206	4.41776792853e-18
ko04728	Dopaminergic synapse	80/1201	185/7206	5.63310998913e-18
ko04024	cAMP signaling pathway	105/1201	279/7206	7.93441806219e-18
ko04723	Retrograde endocannabinoid signaling	73/1201	175/7206	1.77017910716e-15
ko04921	Oxytocin signaling pathway	81/1201	209/7206	8.11205024025e-15
ko04911	Insulin secretion	54/1201	117/7206	6.04120137276e-14
ko04726	Serotonergic synapse	59/1201	137/7206	1.81420425322e-13
ko04261	Adrenergic signaling in cardiomyocytes	74/1201	205/7206	1.19152177905e-11
ko04742	Taste transduction	33/1201	61/7206	2.25091360902e-11
ko03040	Spliceosome	1/1201	145/7206	1.1769412979e-10
ko05031	Amphetamine addiction	41/1201	91/7206	1.70688705494e-10
ko04970	Salivary secretion	42/1201	95/7206	2.13452894757e-10
ko03010	Ribosome	1/1201	129/7206	2.52542480194e-09
ko05322	Systemic lupus erythematosus	3/1201	151/7206	6.92237976165e-09
ko04022	cGMP-PKG signaling pathway	70/1201	216/7206	7.85256819901e-09
ko04720	Long-term potentiation	40/1201	99/7206	1.39187208683e-08
ko04744	Phototransduction	21/1201	36/7206	1.70768027104e-08
ko04925	Aldosterone synthesis and secretion	41/1201	105/7206	3.36234110683e-08
ko03013	RNA transport	6/1201	166/7206	2.33382954913e-07
ko04010	MAPK signaling pathway	88/1201	321/7206	7.3438102903e-07
ko04070	Phosphatidylinositol signaling system	40/1201	112/7206	1.03503922535e-06
ko05168	Herpes simplex infection	9/1201	182/7206	1.61938149696e-06
ko04072	Phospholipase D signaling pathway	59/1201	197/7206	2.45195987982e-06
ko05203	Viral carcinogenesis	20/1201	277/7206	3.42550503271e-06
ko04971	Gastric acid secretion	35/1201	98/7206	3.83325737453e-06
ko04360	Axon guidance	66/1201	233/7206	6.16543681449e-06
ko05030	Cocaine addiction	28/1201	73/7206	8.46484684871e-06
ko04014	Ras signaling pathway	75/1201	279/7206	1.17740654647e-05
ko04514	Cell adhesion molecules (CAMs)	42/1201	130/7206	1.25057640993e-05
ko03008	Ribosome biogenesis in eukaryotes	1/1201	79/7206	1.28298913377e-05
ko04924	Renin secretion	30/1201	86/7206	3.1812218256e-05
ko04972	Pancreatic secretion	36/1201	111/7206	4.72469559655e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	27/1201	74/7206	4.96199995074e-05
ko04141	Protein processing in endoplasmic reticulum	12/1201	184/7206	5.20857342537e-05
ko04740	Olfactory transduction	28/1201	80/7206	5.72588847951e-05
ko04750	Inflammatory mediator regulation of TRP channels	38/1201	122/7206	6.65718915789e-05
ko04060	Cytokine-cytokine receptor interaction	13/1201	191/7206	7.02021195742e-05
ko04923	Regulation of lipolysis in adipocytes	27/1201	77/7206	7.75681159727e-05
ko04966	Collecting duct acid secretion	13/1201	26/7206	8.76882300724e-05
ko04730	Long-term depression	27/1201	78/7206	9.46273284381e-05
ko04540	Gap junction	39/1201	128/7206	9.88966046813e-05
ko05164	Influenza A	11/1201	167/7206	0.000136565030361
ko04745	Phototransduction - fly	16/1201	38/7206	0.000182336355062
ko04976	Bile secretion	27/1201	80/7206	0.00019999566839
ko05414	Dilated cardiomyopathy	34/1201	112/7206	0.000282957828984
ko04915	Estrogen signaling pathway	38/1201	131/7206	0.000339914277164
ko04961	Endocrine and other factor-regulated calcium reabsorption	21/1201	59/7206	0.00034803930733
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	26/1201	79/7206	0.000360924000995
ko05110	Vibrio cholerae infection	22/1201	63/7206	0.000458705844942
ko04621	NOD-like receptor signaling pathway	11/1201	157/7206	0.000475159924775
ko04110	Cell cycle	10/1201	145/7206	0.000668207280543
ko04371	Apelin signaling pathway	47/1201	177/7206	0.000700942713198
ko04930	Type II diabetes mellitus	19/1201	54/7206	0.000784919637144
ko04612	Antigen processing and presentation	3/1201	77/7206	0.00101972370202
ko04626	Plant-pathogen interaction	9/1201	18/7206	0.00111292680059
ko04710	Circadian rhythm	16/1201	43/7206	0.00133388013782
ko04964	Proximal tubule bicarbonate reclamation	12/1201	29/7206	0.00140157158829
ko04120	Ubiquitin mediated proteolysis	10/1201	138/7206	0.00168070147606
ko00240	Pyrimidine metabolism	7/1201	110/7206	0.00183421507044
ko04922	Glucagon signaling pathway	35/1201	128/7206	0.00249434730994
ko04146	Peroxisome	5/1201	89/7206	0.00250146543635
ko04270	Vascular smooth muscle contraction	40/1201	154/7206	0.00297808547543
ko05169	Epstein-Barr virus infection	19/1201	206/7206	0.00309088402172
ko05231	Choline metabolism in cancer	36/1201	134/7206	0.00313885835181
ko04064	NF-kappa B signaling pathway	6/1201	96/7206	0.00353127885223
ko04260	Cardiac muscle contraction	28/1201	98/7206	0.00368722718398
ko05162	Measles	9/1201	120/7206	0.00432791426725
ko05144	Malaria	1/1201	45/7206	0.00434272987093
ko00071	Fatty acid degradation	1/1201	45/7206	0.00434272987093
ko03420	Nucleotide excision repair	1/1201	46/7206	0.00443889708039
ko05140	Leishmaniasis	4/1201	75/7206	0.00476641301552
ko04015	Rap1 signaling pathway	64/1201	278/7206	0.00514753750424
ko00280	Valine, leucine and isoleucine degradation	2/1201	54/7206	0.00560480570725
ko03022	Basal transcription factors	1/1201	44/7206	0.00683109043593
ko04622	RIG-I-like receptor signaling pathway	3/1201	62/7206	0.00922589803685
ko05410	Hypertrophic cardiomyopathy (HCM)	27/1201	100/7206	0.00948122503933
ko04610	Complement and coagulation cascades	5/1201	79/7206	0.0094862497114
ko05205	Proteoglycans in cancer	30/1201	271/7206	0.00995341347937
ko04973	Carbohydrate digestion and absorption	14/1201	42/7206	0.0105673617841
ko04657	IL-17 signaling pathway	6/1201	87/7206	0.012910337286
ko05133	Pertussis	6/1201	87/7206	0.012910337286
ko03410	Base excision repair	1/1201	38/7206	0.0147565462936
ko05145	Toxoplasmosis	11/1201	126/7206	0.0152152531717
ko03018	RNA degradation	6/1201	84/7206	0.0174307830897
ko04960	Aldosterone-regulated sodium reabsorption	13/1201	41/7206	0.0180642764142
ko04115	p53 signaling pathway	5/1201	74/7206	0.0180927523653
ko05321	Inflammatory bowel disease (IBD)	3/1201	56/7206	0.0184761719778
ko04217	Necroptosis	18/1201	178/7206	0.0186013896131
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1201	14/7206	0.0189719838378
ko05214	Glioma	21/1201	79/7206	0.0224043237274
ko05161	Hepatitis B	18/1201	173/7206	0.0230174856293
ko05131	Shigellosis	6/1201	82/7206	0.0239780561758
ko00310	Lysine degradation	5/1201	73/7206	0.0254930746949
ko04912	GnRH signaling pathway	30/1201	122/7206	0.0264285653415
ko00480	Glutathione metabolism	3/1201	55/7206	0.0270611679782
ko00562	Inositol phosphate metabolism	23/1201	89/7206	0.030324933956
ko04722	Neurotrophin signaling pathway	37/1201	160/7206	0.03157572478
ko03320	PPAR signaling pathway	5/1201	69/7206	0.0339459000028
ko00860	Porphyrin and chlorophyll metabolism	1/1201	34/7206	0.0340659893393
ko05230	Central carbon metabolism in cancer	21/1201	81/7206	0.0343083166449
ko00330	Arginine and proline metabolism	4/1201	61/7206	0.0364386902982
ko04666	Fc gamma R-mediated phagocytosis	29/1201	122/7206	0.0374665220723
ko00590	Arachidonic acid metabolism	3/1201	52/7206	0.0376080854546
ko04213	Longevity regulating pathway - multiple species	22/1201	86/7206	0.0398795095876
ko04916	Melanogenesis	33/1201	142/7206	0.0401266592164
ko00512	Mucin type O-glycan biosynthesis	9/1201	29/7206	0.0459822866784
ko05340	Primary immunodeficiency	1/1201	30/7206	0.0487369220887