ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	77/602	145/7206	1.16841100678e-45
ko03013	RNA transport	53/602	166/7206	1.06521253094e-18
ko03030	DNA replication	24/602	38/7206	2.73579902733e-17
ko04110	Cell cycle	46/602	145/7206	3.04735311518e-16
ko04080	Neuroactive ligand-receptor interaction	1/602	423/7206	2.35932902926e-15
ko04111	Cell cycle - yeast	33/602	90/7206	5.07779387127e-14
ko03015	mRNA surveillance pathway	32/602	93/7206	9.48040267569e-13
ko03050	Proteasome	21/602	54/7206	6.10166060756e-10
ko03420	Nucleotide excision repair	19/602	46/7206	1.20536935725e-09
ko03008	Ribosome biogenesis in eukaryotes	25/602	79/7206	2.282785485e-09
ko04020	Calcium signaling pathway	1/602	265/7206	2.52595110292e-09
ko04113	Meiosis - yeast	23/602	70/7206	4.44156165877e-09
ko03022	Basal transcription factors	17/602	44/7206	3.03547160805e-08
ko03430	Mismatch repair	12/602	22/7206	3.07794852256e-08
ko00240	Pyrimidine metabolism	26/602	110/7206	7.82785005105e-07
ko03410	Base excision repair	14/602	38/7206	1.01551742268e-06
ko05169	Epstein-Barr virus infection	38/602	206/7206	2.39054839385e-06
ko03018	RNA degradation	21/602	84/7206	3.47780054656e-06
ko04723	Retrograde endocannabinoid signaling	1/602	175/7206	5.58352674743e-06
ko05010	Alzheimer's disease	2/602	202/7206	6.88845155092e-06
ko04144	Endocytosis	9/602	342/7206	1.32596759933e-05
ko04921	Oxytocin signaling pathway	3/602	209/7206	2.12045441607e-05
ko04022	cGMP-PKG signaling pathway	4/602	216/7206	8.21544519949e-05
ko04932	Non-alcoholic fatty liver disease (NAFLD)	3/602	182/7206	0.000192098772633
ko04621	NOD-like receptor signaling pathway	2/602	157/7206	0.000205725607188
ko03460	Fanconi anemia pathway	13/602	51/7206	0.0002062060078
ko04725	Cholinergic synapse	2/602	160/7206	0.000217176543418
ko04024	cAMP signaling pathway	8/602	279/7206	0.000232395246971
ko04120	Ubiquitin mediated proteolysis	25/602	138/7206	0.000233689278741
ko05012	Parkinson's disease	2/602	155/7206	0.000313687060697
ko04072	Phospholipase D signaling pathway	4/602	197/7206	0.000337551077551
ko03020	RNA polymerase	9/602	29/7206	0.000406954434565
ko05166	HTLV-I infection	42/602	292/7206	0.000474920072411
ko04911	Insulin secretion	1/602	117/7206	0.000628425894058
ko04261	Adrenergic signaling in cardiomyocytes	5/602	205/7206	0.000737418529423
ko04713	Circadian entrainment	2/602	136/7206	0.00138527244745
ko03440	Homologous recombination	10/602	41/7206	0.00159410097889
ko04270	Vascular smooth muscle contraction	3/602	154/7206	0.00165567420592
ko04910	Insulin signaling pathway	4/602	172/7206	0.00184879794065
ko04915	Estrogen signaling pathway	2/602	131/7206	0.00198563111421
ko04720	Long-term potentiation	1/602	99/7206	0.00293643847984
ko00230	Purine metabolism	28/602	194/7206	0.00360388788802
ko05217	Basal cell carcinoma	13/602	68/7206	0.00363559053811
ko04371	Apelin signaling pathway	5/602	177/7206	0.00368814595404
ko04974	Protein digestion and absorption	1/602	96/7206	0.00440564286398
ko04650	Natural killer cell mediated cytotoxicity	1/602	97/7206	0.00451564147662
ko04931	Insulin resistance	3/602	137/7206	0.00453219621858
ko04330	Notch signaling pathway	12/602	62/7206	0.00461099547016
ko05414	Dilated cardiomyopathy	2/602	112/7206	0.00556005880471
ko04920	Adipocytokine signaling pathway	1/602	89/7206	0.00628928879953
ko05031	Amphetamine addiction	1/602	91/7206	0.00642151790737
ko05231	Choline metabolism in cancer	3/602	134/7206	0.00651743251836
ko04728	Dopaminergic synapse	6/602	185/7206	0.00686942954008
ko04068	FoxO signaling pathway	5/602	167/7206	0.00692152762884
ko05034	Alcoholism	9/602	238/7206	0.00819464985521
ko04810	Regulation of actin cytoskeleton	11/602	264/7206	0.00896384653962
ko04922	Glucagon signaling pathway	3/602	128/7206	0.00899812779415
ko04540	Gap junction	3/602	128/7206	0.00899812779415
ko04062	Chemokine signaling pathway	7/602	201/7206	0.00906489373964
ko04924	Renin secretion	1/602	86/7206	0.00935094499256
ko04925	Aldosterone synthesis and secretion	2/602	105/7206	0.0115058733607
ko04750	Inflammatory mediator regulation of TRP channels	3/602	122/7206	0.0124649461803
ko04066	HIF-1 signaling pathway	3/602	123/7206	0.012567024223
ko04010	MAPK signaling pathway	15/602	321/7206	0.0128720242111
ko04976	Bile secretion	1/602	80/7206	0.0134494708546
ko04138	Autophagy - yeast	1/602	81/7206	0.0136017260579
ko04712	Circadian rhythm - plant	3/602	7/7206	0.0157279349299
ko05146	Amoebiasis	2/602	99/7206	0.0161432877675
ko05410	Hypertrophic cardiomyopathy (HCM)	2/602	100/7206	0.0163235835729
ko04380	Osteoclast differentiation	4/602	134/7206	0.0176327420719
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	6/602	26/7206	0.0179710391822
ko04151	PI3K-Akt signaling pathway	20/602	390/7206	0.0181525984771
ko04114	Oocyte meiosis	20/602	139/7206	0.0186005635665
ko05140	Leishmaniasis	1/602	75/7206	0.0195656735041
ko04923	Regulation of lipolysis in adipocytes	1/602	77/7206	0.02010140312
ko04015	Rap1 signaling pathway	13/602	278/7206	0.0201486037696
ko04014	Ras signaling pathway	13/602	279/7206	0.020149313186
ko04310	Wnt signaling pathway	24/602	181/7206	0.0204110500896
ko04730	Long-term depression	1/602	78/7206	0.0205923856632
ko04972	Pancreatic secretion	3/602	111/7206	0.0240195813495
ko03010	Ribosome	4/602	129/7206	0.0240832748119
ko04514	Cell adhesion molecules (CAMs)	4/602	130/7206	0.0241429352951
ko04217	Necroptosis	7/602	178/7206	0.0275998256621
ko03320	PPAR signaling pathway	1/602	69/7206	0.0283744719915
ko05030	Cocaine addiction	1/602	73/7206	0.0297698121245
ko04611	Platelet activation	6/602	163/7206	0.0301986694606
ko04662	B cell receptor signaling pathway	2/602	88/7206	0.0321229134995
ko04146	Peroxisome	2/602	89/7206	0.0322657989662
ko04659	Th17 cell differentiation	3/602	106/7206	0.0332090001038
ko04612	Antigen processing and presentation	12/602	77/7206	0.034463834673
ko05168	Herpes simplex infection	23/602	182/7206	0.0411202991817
ko04640	Hematopoietic cell lineage	1/602	64/7206	0.0411606299196
ko05152	Tuberculosis	8/602	187/7206	0.0433178743447
ko04668	TNF signaling pathway	4/602	120/7206	0.0445247487965
ko04912	GnRH signaling pathway	4/602	122/7206	0.0452974462857
ko04211	Longevity regulating pathway	4/602	123/7206	0.0459278977769
ko04918	Thyroid hormone synthesis	2/602	86/7206	0.0464860774259
ko05133	Pertussis	2/602	87/7206	0.0473801536519