ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	97/581	423/7206	9.99761818088e-23
ko05033	Nicotine addiction	32/581	56/7206	3.12225649271e-21
ko04724	Glutamatergic synapse	50/581	152/7206	5.53223223908e-19
ko05032	Morphine addiction	40/581	110/7206	3.86910263613e-17
ko04727	GABAergic synapse	38/581	110/7206	1.74767978158e-15
ko04723	Retrograde endocannabinoid signaling	44/581	175/7206	3.60558213821e-12
ko04024	cAMP signaling pathway	58/581	279/7206	7.0040557639e-12
ko04721	Synaptic vesicle cycle	27/581	80/7206	4.32187741966e-11
ko04713	Circadian entrainment	35/581	136/7206	3.15664293362e-10
ko04728	Dopaminergic synapse	41/581	185/7206	1.33658755711e-09
ko04742	Taste transduction	20/581	61/7206	2.62232541709e-08
ko04911	Insulin secretion	28/581	117/7206	1.05598247873e-07
ko05030	Cocaine addiction	21/581	73/7206	1.52022085811e-07
ko04725	Cholinergic synapse	33/581	160/7206	3.43880940795e-07
ko04020	Calcium signaling pathway	46/581	265/7206	4.37716634844e-07
ko04010	MAPK signaling pathway	52/581	321/7206	8.57545096562e-07
ko04514	Cell adhesion molecules (CAMs)	28/581	130/7206	1.08056066693e-06
ko04261	Adrenergic signaling in cardiomyocytes	36/581	205/7206	6.19594388474e-06
ko04726	Serotonergic synapse	27/581	137/7206	9.92501884228e-06
ko04360	Axon guidance	39/581	233/7206	1.16997842221e-05
ko04921	Oxytocin signaling pathway	36/581	209/7206	1.25008170382e-05
ko04972	Pancreatic secretion	22/581	111/7206	5.9924825437e-05
ko05031	Amphetamine addiction	19/581	91/7206	9.10718472574e-05
ko04720	Long-term potentiation	20/581	99/7206	9.74513034738e-05
ko03040	Spliceosome	1/581	145/7206	0.00014202833024
ko04970	Salivary secretion	19/581	95/7206	0.000166500391305
ko04621	NOD-like receptor signaling pathway	2/581	157/7206	0.000303109719434
ko05203	Viral carcinogenesis	8/581	277/7206	0.000438144273761
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/581	14/7206	0.000458186937287
ko05322	Systemic lupus erythematosus	2/581	151/7206	0.000676420263848
ko05014	Amyotrophic lateral sclerosis (ALS)	15/581	74/7206	0.000685114473257
ko04072	Phospholipase D signaling pathway	30/581	197/7206	0.000738138505601
ko03013	RNA transport	3/581	166/7206	0.000805307698636
ko04141	Protein processing in endoplasmic reticulum	4/581	184/7206	0.00135232151089
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	15/581	79/7206	0.00139007622905
ko05205	Proteoglycans in cancer	9/581	271/7206	0.00195976560339
ko00240	Pyrimidine metabolism	1/581	110/7206	0.00210663397455
ko04060	Cytokine-cytokine receptor interaction	5/581	191/7206	0.00272961561764
ko01200	Carbon metabolism	2/581	128/7206	0.00275428474537
ko05164	Influenza A	4/581	167/7206	0.0035948089787
ko05414	Dilated cardiomyopathy	18/581	112/7206	0.00429630991111
ko04540	Gap junction	20/581	128/7206	0.00446418595116
ko04730	Long-term depression	14/581	78/7206	0.00479549832192
ko04217	Necroptosis	5/581	178/7206	0.00511217766863
ko04915	Estrogen signaling pathway	20/581	131/7206	0.005115733743
ko04022	cGMP-PKG signaling pathway	29/581	216/7206	0.00707317209759
ko05169	Epstein-Barr virus infection	7/581	206/7206	0.00901337586463
ko04923	Regulation of lipolysis in adipocytes	13/581	77/7206	0.00950421461672
ko04925	Aldosterone synthesis and secretion	16/581	105/7206	0.0109288950973
ko05168	Herpes simplex infection	6/581	182/7206	0.0125726802969
ko00515	Mannose type O-glycan biosynthesis	6/581	25/7206	0.0125908473584
ko04071	Sphingolipid signaling pathway	22/581	162/7206	0.0129270038817
ko03018	RNA degradation	1/581	84/7206	0.0137459211736
ko04260	Cardiac muscle contraction	15/581	98/7206	0.0137938853135
ko04218	Cellular senescence	6/581	177/7206	0.0168521387356
ko00510	N-Glycan biosynthesis	9/581	50/7206	0.0170811633767
ko00513	Various types of N-glycan biosynthesis	8/581	42/7206	0.017332218723
ko04612	Antigen processing and presentation	1/581	77/7206	0.019684655803
ko04064	NF-kappa B signaling pathway	2/581	96/7206	0.0229240101821
ko04120	Ubiquitin mediated proteolysis	4/581	138/7206	0.0251846621154
ko04964	Proximal tubule bicarbonate reclamation	6/581	29/7206	0.0256832600166
ko02024	Quorum sensing	4/581	15/7206	0.0278725018698
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	4/581	15/7206	0.0278725018698
ko00310	Lysine degradation	1/581	73/7206	0.0287241331938
ko04630	Jak-STAT signaling pathway	4/581	132/7206	0.0338248826196
ko05231	Choline metabolism in cancer	18/581	134/7206	0.0349664006748
ko04971	Gastric acid secretion	14/581	98/7206	0.0365714627089
ko04930	Type II diabetes mellitus	9/581	54/7206	0.0377512253887
ko05410	Hypertrophic cardiomyopathy (HCM)	14/581	100/7206	0.0392771779926
ko04940	Type I diabetes mellitus	6/581	32/7206	0.0399606932225
ko04015	Rap1 signaling pathway	32/581	278/7206	0.0420377319857
ko04110	Cell cycle	5/581	145/7206	0.0431096175639
ko04666	Fc gamma R-mediated phagocytosis	16/581	122/7206	0.0442763188953
ko05145	Toxoplasmosis	4/581	126/7206	0.0453666553464
ko04146	Peroxisome	2/581	89/7206	0.0467038606899
ko04962	Vasopressin-regulated water reabsorption	9/581	58/7206	0.0485715085531