ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	136/792	423/7206	3.03622999474e-34
ko04724	Glutamatergic synapse	67/792	152/7206	6.75559761774e-26
ko05033	Nicotine addiction	37/792	56/7206	8.36077515212e-23
ko04728	Dopaminergic synapse	69/792	185/7206	1.45524873481e-21
ko04721	Synaptic vesicle cycle	42/792	80/7206	3.16649926329e-20
ko05032	Morphine addiction	48/792	110/7206	1.30656901861e-18
ko04713	Circadian entrainment	53/792	136/7206	8.94812691722e-18
ko04725	Cholinergic synapse	58/792	160/7206	1.35118290375e-17
ko04727	GABAergic synapse	45/792	110/7206	3.26024247489e-16
ko04723	Retrograde endocannabinoid signaling	59/792	175/7206	3.56299375857e-16
ko04024	cAMP signaling pathway	76/792	279/7206	1.51176084724e-14
ko04726	Serotonergic synapse	46/792	137/7206	8.58286901727e-13
ko04911	Insulin secretion	41/792	117/7206	3.17544776517e-12
ko04921	Oxytocin signaling pathway	56/792	209/7206	1.04776752973e-10
ko04261	Adrenergic signaling in cardiomyocytes	55/792	205/7206	1.51165466476e-10
ko05031	Amphetamine addiction	32/792	91/7206	7.20107150551e-10
ko04020	Calcium signaling pathway	63/792	265/7206	1.39479887778e-09
ko04720	Long-term potentiation	31/792	99/7206	3.16341732641e-08
ko05030	Cocaine addiction	24/792	73/7206	4.18433555126e-07
ko04970	Salivary secretion	28/792	95/7206	5.99638405628e-07
ko04742	Taste transduction	21/792	61/7206	9.36917561168e-07
ko04360	Axon guidance	51/792	233/7206	1.02284327511e-06
ko04971	Gastric acid secretion	28/792	98/7206	1.20476458846e-06
ko03040	Spliceosome	1/792	145/7206	1.30956474514e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	23/792	74/7206	2.20800710872e-06
ko04010	MAPK signaling pathway	63/792	321/7206	3.72589618042e-06
ko04966	Collecting duct acid secretion	12/792	26/7206	6.40041797282e-06
ko04514	Cell adhesion molecules (CAMs)	32/792	130/7206	1.14259557064e-05
ko04744	Phototransduction	14/792	36/7206	1.24998427389e-05
ko04120	Ubiquitin mediated proteolysis	2/792	138/7206	2.54409811231e-05
ko04925	Aldosterone synthesis and secretion	26/792	105/7206	5.16423406502e-05
ko05322	Systemic lupus erythematosus	3/792	151/7206	5.52520069595e-05
ko05168	Herpes simplex infection	5/792	182/7206	5.73253549619e-05
ko04730	Long-term depression	21/792	78/7206	6.81083137707e-05
ko03013	RNA transport	4/792	166/7206	7.18685567436e-05
ko04972	Pancreatic secretion	27/792	111/7206	8.03196626804e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/792	79/7206	8.33670899288e-05
ko05203	Viral carcinogenesis	12/792	277/7206	0.000112304888661
ko04260	Cardiac muscle contraction	24/792	98/7206	0.000120558070971
ko04745	Phototransduction - fly	13/792	38/7206	0.000121725616644
ko04022	cGMP-PKG signaling pathway	42/792	216/7206	0.000221209899759
ko04540	Gap junction	28/792	128/7206	0.000291801439306
ko05110	Vibrio cholerae infection	17/792	63/7206	0.000320454458664
ko04060	Cytokine-cytokine receptor interaction	7/792	191/7206	0.000372519133921
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/792	59/7206	0.000449044253423
ko04915	Estrogen signaling pathway	28/792	131/7206	0.0005544499058
ko04070	Phosphatidylinositol signaling system	25/792	112/7206	0.000601259717555
ko04621	NOD-like receptor signaling pathway	5/792	157/7206	0.000658065738971
ko04964	Proximal tubule bicarbonate reclamation	10/792	29/7206	0.000689796101962
ko04141	Protein processing in endoplasmic reticulum	7/792	184/7206	0.000714739501564
ko04750	Inflammatory mediator regulation of TRP channels	26/792	122/7206	0.00105515609187
ko05414	Dilated cardiomyopathy	24/792	112/7206	0.001141733496
ko04014	Ras signaling pathway	48/792	279/7206	0.00164463021443
ko04610	Complement and coagulation cascades	1/792	79/7206	0.00175646539283
ko04626	Plant-pathogen interaction	7/792	18/7206	0.00201742434056
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/792	14/7206	0.0023862971225
ko05164	Influenza A	7/792	167/7206	0.00246120509214
ko04924	Renin secretion	19/792	86/7206	0.00259428409654
ko04612	Antigen processing and presentation	1/792	77/7206	0.0026775143521
ko04146	Peroxisome	2/792	89/7206	0.00346926171164
ko04072	Phospholipase D signaling pathway	35/792	197/7206	0.00365529540299
ko04740	Olfactory transduction	17/792	80/7206	0.00630981579037
ko04071	Sphingolipid signaling pathway	29/792	162/7206	0.00723791605852
ko04064	NF-kappa B signaling pathway	3/792	96/7206	0.00809446139957
ko04640	Hematopoietic cell lineage	1/792	64/7206	0.00832956557671
ko04960	Aldosterone-regulated sodium reabsorption	10/792	41/7206	0.0114384804928
ko00561	Glycerolipid metabolism	1/792	63/7206	0.0129276526756
ko04930	Type II diabetes mellitus	12/792	54/7206	0.0144082213071
ko05140	Leishmaniasis	2/792	75/7206	0.01478954094
ko05120	Epithelial cell signaling in Helicobacter pylori infection	18/792	92/7206	0.0170185797583
ko05230	Central carbon metabolism in cancer	16/792	81/7206	0.0184673097965
ko04973	Carbohydrate digestion and absorption	10/792	42/7206	0.020987962933
ko00310	Lysine degradation	2/792	73/7206	0.021727388726
ko00280	Valine, leucine and isoleucine degradation	1/792	54/7206	0.026608268499
ko04114	Oocyte meiosis	24/792	139/7206	0.0270315510443
ko05214	Glioma	15/792	79/7206	0.0292124785975
ko00240	Pyrimidine metabolism	5/792	110/7206	0.0299066440962
ko05010	Alzheimer's disease	32/792	202/7206	0.0299380411318
ko04015	Rap1 signaling pathway	42/792	278/7206	0.0309481286058
ko04110	Cell cycle	8/792	145/7206	0.0312447491552
ko05410	Hypertrophic cardiomyopathy (HCM)	18/792	100/7206	0.0344137629063
ko05210	Colorectal cancer	16/792	86/7206	0.0349467197521
ko05205	Proteoglycans in cancer	19/792	271/7206	0.0368548415741
ko00590	Arachidonic acid metabolism	1/792	52/7206	0.0406739118014
ko04012	ErbB signaling pathway	19/792	109/7206	0.0427842967859
ko05034	Alcoholism	36/792	238/7206	0.0446762177082
ko04976	Bile secretion	15/792	80/7206	0.044944397768
ko00910	Nitrogen metabolism	5/792	19/7206	0.049769994382