ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	122/835	423/7206	1.89065473563e-23
ko04724	Glutamatergic synapse	65/835	152/7206	6.15629457296e-23
ko05033	Nicotine addiction	37/835	56/7206	5.46199516438e-22
ko04721	Synaptic vesicle cycle	42/835	80/7206	2.40998017667e-19
ko04728	Dopaminergic synapse	65/835	185/7206	1.43813071005e-17
ko05032	Morphine addiction	44/835	110/7206	1.34615620648e-14
ko04713	Circadian entrainment	49/835	136/7206	5.24788123942e-14
ko04727	GABAergic synapse	43/835	110/7206	7.09989596623e-14
ko04725	Cholinergic synapse	51/835	160/7206	3.79619160066e-12
ko04723	Retrograde endocannabinoid signaling	53/835	175/7206	1.32032164817e-11
ko04360	Axon guidance	62/835	233/7206	1.14248810375e-10
ko04024	cAMP signaling pathway	68/835	279/7206	1.27685552477e-09
ko04911	Insulin secretion	36/835	117/7206	1.70767572389e-08
ko05030	Cocaine addiction	26/835	73/7206	6.36317445832e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	26/835	74/7206	8.74920007457e-08
ko04744	Phototransduction	17/835	36/7206	1.05568089664e-07
ko05031	Amphetamine addiction	29/835	91/7206	1.8263853734e-07
ko04726	Serotonergic synapse	38/835	137/7206	1.89322004796e-07
ko03040	Spliceosome	1/835	145/7206	5.46097904113e-07
ko04261	Adrenergic signaling in cardiomyocytes	48/835	205/7206	1.20098960043e-06
ko04060	Cytokine-cytokine receptor interaction	4/835	191/7206	1.62831783202e-06
ko04742	Taste transduction	21/835	61/7206	2.23934911039e-06
ko04514	Cell adhesion molecules (CAMs)	34/835	130/7206	4.69254543429e-06
ko05168	Herpes simplex infection	5/835	182/7206	1.88008428536e-05
ko03013	RNA transport	4/835	166/7206	2.18512473174e-05
ko05203	Viral carcinogenesis	12/835	277/7206	3.12665269518e-05
ko04010	MAPK signaling pathway	62/835	321/7206	3.52892352695e-05
ko04720	Long-term potentiation	26/835	99/7206	4.40940962377e-05
ko04966	Collecting duct acid secretion	11/835	26/7206	7.04660854425e-05
ko04120	Ubiquitin mediated proteolysis	3/835	138/7206	7.37273441021e-05
ko04970	Salivary secretion	24/835	95/7206	0.000254225310249
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/835	59/7206	0.000256124233926
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/835	14/7206	0.000449877617257
ko04621	NOD-like receptor signaling pathway	6/835	157/7206	0.000915087083232
ko04141	Protein processing in endoplasmic reticulum	8/835	184/7206	0.000955474050766
ko01200	Carbon metabolism	4/835	128/7206	0.00112928002978
ko03008	Ribosome biogenesis in eukaryotes	1/835	79/7206	0.00115316248558
ko05164	Influenza A	7/835	167/7206	0.00129905172523
ko04921	Oxytocin signaling pathway	40/835	209/7206	0.00131836151083
ko05322	Systemic lupus erythematosus	6/835	151/7206	0.00178556004563
ko04730	Long-term depression	19/835	78/7206	0.00187486134837
ko04915	Estrogen signaling pathway	27/835	131/7206	0.00229514989563
ko04146	Peroxisome	2/835	89/7206	0.00233344764878
ko04022	cGMP-PKG signaling pathway	39/835	216/7206	0.00469559221629
ko05110	Vibrio cholerae infection	15/835	63/7206	0.00506559344769
ko03018	RNA degradation	2/835	84/7206	0.00511580568257
ko04640	Hematopoietic cell lineage	1/835	64/7206	0.00551444716248
ko04064	NF-kappa B signaling pathway	3/835	96/7206	0.00565909103494
ko04962	Vasopressin-regulated water reabsorption	14/835	58/7206	0.00617271198889
ko04972	Pancreatic secretion	23/835	111/7206	0.00632037407719
ko04932	Non-alcoholic fatty liver disease (NAFLD)	10/835	182/7206	0.00671025841704
ko04540	Gap junction	25/835	128/7206	0.0076441976912
ko00561	Glycerolipid metabolism	1/835	63/7206	0.00850026357902
ko04924	Renin secretion	18/835	86/7206	0.0104624787239
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	17/835	79/7206	0.0116632742541
ko04014	Ras signaling pathway	46/835	279/7206	0.0127587063926
ko04020	Calcium signaling pathway	44/835	265/7206	0.0140176843609
ko04950	Maturity onset diabetes of the young	8/835	29/7206	0.0146064146077
ko05205	Proteoglycans in cancer	19/835	271/7206	0.015215066837
ko00240	Pyrimidine metabolism	5/835	110/7206	0.015764142944
ko00280	Valine, leucine and isoleucine degradation	1/835	54/7206	0.0176472148382
ko00480	Glutathione metabolism	1/835	55/7206	0.0178895529625
ko05162	Measles	6/835	120/7206	0.0204949173552
ko05120	Epithelial cell signaling in Helicobacter pylori infection	18/835	92/7206	0.0214036457494
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/835	15/7206	0.022949263518
ko04217	Necroptosis	11/835	178/7206	0.0233569231703
ko04971	Gastric acid secretion	19/835	98/7206	0.0243247285133
ko00380	Tryptophan metabolism	1/835	50/7206	0.0258755676595
ko00590	Arachidonic acid metabolism	1/835	52/7206	0.0265983734148
ko05169	Epstein-Barr virus infection	14/835	206/7206	0.0269291081656
ko04350	TGF-beta signaling pathway	5/835	103/7206	0.029019456091
ko04612	Antigen processing and presentation	3/835	77/7206	0.0305809148617
ko05145	Toxoplasmosis	7/835	126/7206	0.0338988754973
ko04974	Protein digestion and absorption	18/835	96/7206	0.0355980510839
ko04550	Signaling pathways regulating pluripotency of stem cells	28/835	165/7206	0.035721493856
ko03420	Nucleotide excision repair	1/835	46/7206	0.0379661272373
ko05204	Chemical carcinogenesis	1/835	48/7206	0.0385125011988
ko05034	Alcoholism	38/835	238/7206	0.0387956728651
ko00564	Glycerophospholipid metabolism	5/835	99/7206	0.0390329455753
ko05224	Breast cancer	29/835	174/7206	0.0408643516264
ko00010	Glycolysis / Gluconeogenesis	3/835	74/7206	0.0427068641433
ko05140	Leishmaniasis	3/835	75/7206	0.0433874663079
ko04391	Hippo signaling pathway - fly	17/835	90/7206	0.0441830986817
ko04145	Phagosome	27/835	162/7206	0.0466604575599
ko04110	Cell cycle	9/835	145/7206	0.0477732392138