ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	191/1180	423/7206	3.27198488806e-47
ko04724	Glutamatergic synapse	90/1180	152/7206	1.03290084636e-33
ko05033	Nicotine addiction	48/1180	56/7206	3.13187926311e-30
ko05032	Morphine addiction	68/1180	110/7206	2.88107549614e-27
ko04727	GABAergic synapse	66/1180	110/7206	2.02404876613e-25
ko04713	Circadian entrainment	74/1180	136/7206	1.14032142681e-24
ko04721	Synaptic vesicle cycle	52/1180	80/7206	1.3829696913e-22
ko04728	Dopaminergic synapse	83/1180	185/7206	2.40024162051e-20
ko04725	Cholinergic synapse	75/1180	160/7206	7.28466595847e-20
ko04723	Retrograde endocannabinoid signaling	79/1180	175/7206	1.29199535549e-19
ko04024	cAMP signaling pathway	105/1180	279/7206	1.97249935648e-18
ko04742	Taste transduction	39/1180	61/7206	7.1708690904e-17
ko04020	Calcium signaling pathway	98/1180	265/7206	1.36815966861e-16
ko04921	Oxytocin signaling pathway	81/1180	209/7206	4.02800555484e-15
ko04911	Insulin secretion	54/1180	117/7206	2.82704744279e-14
ko04744	Phototransduction	25/1180	36/7206	1.73128266797e-12
ko04261	Adrenergic signaling in cardiomyocytes	74/1180	205/7206	3.81019709776e-12
ko04726	Serotonergic synapse	56/1180	137/7206	4.75766280085e-12
ko04970	Salivary secretion	43/1180	95/7206	2.7860687652e-11
ko05031	Amphetamine addiction	41/1180	91/7206	9.68482806584e-11
ko04720	Long-term potentiation	43/1180	99/7206	1.454074487e-10
ko03040	Spliceosome	1/1180	145/7206	1.93136031773e-10
ko04360	Axon guidance	74/1180	233/7206	4.01576772293e-09
ko05203	Viral carcinogenesis	15/1180	277/7206	2.89401207695e-08
ko04022	cGMP-PKG signaling pathway	67/1180	216/7206	5.94117713415e-08
ko04925	Aldosterone synthesis and secretion	40/1180	105/7206	6.47709428953e-08
ko04060	Cytokine-cytokine receptor interaction	8/1180	191/7206	2.53701925478e-07
ko04971	Gastric acid secretion	37/1180	98/7206	2.62174964215e-07
ko05030	Cocaine addiction	30/1180	73/7206	3.94001666281e-07
ko05168	Herpes simplex infection	8/1180	182/7206	7.27474733488e-07
ko05164	Influenza A	7/1180	167/7206	1.28934339167e-06
ko03013	RNA transport	7/1180	166/7206	1.93018520413e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	29/1180	74/7206	1.98233088917e-06
ko05322	Systemic lupus erythematosus	6/1180	151/7206	3.34422208559e-06
ko04740	Olfactory transduction	30/1180	80/7206	4.44052421986e-06
ko04924	Renin secretion	31/1180	86/7206	1.04167934781e-05
ko04966	Collecting duct acid secretion	14/1180	26/7206	1.27061667323e-05
ko04070	Phosphatidylinositol signaling system	37/1180	112/7206	1.33042983303e-05
ko04514	Cell adhesion molecules (CAMs)	41/1180	130/7206	1.90914709913e-05
ko04610	Complement and coagulation cascades	1/1180	79/7206	2.03533526137e-05
ko04621	NOD-like receptor signaling pathway	8/1180	157/7206	2.55945395543e-05
ko04141	Protein processing in endoplasmic reticulum	11/1180	184/7206	2.82218307848e-05
ko05414	Dilated cardiomyopathy	36/1180	112/7206	2.89282287578e-05
ko04010	MAPK signaling pathway	81/1180	321/7206	3.79315556773e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	28/1180	79/7206	3.88541373544e-05
ko05169	Epstein-Barr virus infection	14/1180	206/7206	5.12192715546e-05
ko04972	Pancreatic secretion	35/1180	111/7206	7.46874044103e-05
ko05110	Vibrio cholerae infection	23/1180	63/7206	9.60683588033e-05
ko04745	Phototransduction - fly	16/1180	38/7206	0.000147236608186
ko04540	Gap junction	38/1180	128/7206	0.000148504824999
ko04923	Regulation of lipolysis in adipocytes	26/1180	77/7206	0.000149991354416
ko03008	Ribosome biogenesis in eukaryotes	2/1180	79/7206	0.000171962627254
ko05162	Measles	6/1180	120/7206	0.000247911585784
ko04120	Ubiquitin mediated proteolysis	8/1180	138/7206	0.000267389220279
ko04072	Phospholipase D signaling pathway	52/1180	197/7206	0.000274888747939
ko04976	Bile secretion	26/1180	80/7206	0.000349576187435
ko05161	Hepatitis B	12/1180	173/7206	0.000352528641985
ko05140	Leishmaniasis	2/1180	75/7206	0.000399408509349
ko05205	Proteoglycans in cancer	24/1180	271/7206	0.000405208167982
ko04064	NF-kappa B signaling pathway	4/1180	96/7206	0.000408162224835
ko04371	Apelin signaling pathway	47/1180	177/7206	0.00044262764079
ko04260	Cardiac muscle contraction	30/1180	98/7206	0.000461525353934
ko04730	Long-term depression	25/1180	78/7206	0.000555548232871
ko04110	Cell cycle	10/1180	145/7206	0.000926266131928
ko04626	Plant-pathogen interaction	9/1180	18/7206	0.000975257813079
ko04915	Estrogen signaling pathway	36/1180	131/7206	0.00115892730435
ko04750	Inflammatory mediator regulation of TRP channels	34/1180	122/7206	0.00119265963749
ko04014	Ras signaling pathway	66/1180	279/7206	0.00125621975058
ko04612	Antigen processing and presentation	3/1180	77/7206	0.00158134444102
ko04961	Endocrine and other factor-regulated calcium reabsorption	19/1180	59/7206	0.00228683996527
ko00240	Pyrimidine metabolism	7/1180	110/7206	0.00257718125158
ko00330	Arginine and proline metabolism	2/1180	61/7206	0.00265365959011
ko04146	Peroxisome	5/1180	89/7206	0.00356995924878
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/1180	14/7206	0.00367095069214
ko05410	Hypertrophic cardiomyopathy (HCM)	28/1180	100/7206	0.00378532567431
ko04630	Jak-STAT signaling pathway	10/1180	132/7206	0.0041268489457
ko04964	Proximal tubule bicarbonate reclamation	11/1180	29/7206	0.00428685077215
ko03420	Nucleotide excision repair	1/1180	46/7206	0.00441287845763
ko00480	Glutathione metabolism	2/1180	55/7206	0.00568046107053
ko05321	Inflammatory bowel disease (IBD)	2/1180	56/7206	0.00571977511963
ko03022	Basal transcription factors	1/1180	44/7206	0.0066963293771
ko03018	RNA degradation	5/1180	84/7206	0.00697459905458
ko05144	Malaria	1/1180	45/7206	0.00702070292752
ko00071	Fatty acid degradation	1/1180	45/7206	0.00702070292752
ko05145	Toxoplasmosis	10/1180	126/7206	0.00730879545358
ko04270	Vascular smooth muscle contraction	38/1180	154/7206	0.00783670803752
ko04932	Non-alcoholic fatty liver disease (NAFLD)	17/1180	182/7206	0.00806006326771
ko04622	RIG-I-like receptor signaling pathway	3/1180	62/7206	0.00921479659327
ko04640	Hematopoietic cell lineage	3/1180	64/7206	0.00965146604009
ko04214	Apoptosis - fly	4/1180	72/7206	0.00965150383561
ko05131	Shigellosis	5/1180	82/7206	0.00981804993026
ko00310	Lysine degradation	4/1180	73/7206	0.00990017726384
ko04916	Melanogenesis	35/1180	142/7206	0.0111877522287
ko00380	Tryptophan metabolism	2/1180	50/7206	0.0120805899729
ko04658	Th1 and Th2 cell differentiation	7/1180	96/7206	0.0121155999995
ko04918	Thyroid hormone synthesis	23/1180	86/7206	0.0124357720513
ko00590	Arachidonic acid metabolism	2/1180	52/7206	0.0126803666987
ko04657	IL-17 signaling pathway	6/1180	87/7206	0.0127896619431
ko05133	Pertussis	6/1180	87/7206	0.0127896619431
ko05215	Prostate cancer	9/1180	111/7206	0.0139857716699
ko00630	Glyoxylate and dicarboxylate metabolism	1/1180	38/7206	0.0148478507879
ko00260	Glycine, serine and threonine metabolism	2/1180	48/7206	0.0175983997426
ko05219	Bladder cancer	2/1180	48/7206	0.0175983997426
ko01524	Platinum drug resistance	5/1180	76/7206	0.0183964160411
ko04912	GnRH signaling pathway	30/1180	122/7206	0.0184216431433
ko04620	Toll-like receptor signaling pathway	8/1180	100/7206	0.0202034816229
ko04115	p53 signaling pathway	5/1180	74/7206	0.0255366074481
ko04114	Oocyte meiosis	33/1180	139/7206	0.0269818285439
ko05222	Small cell lung cancer	7/1180	89/7206	0.0295154576486
ko04210	Apoptosis	19/1180	180/7206	0.0319210167385
ko04140	Autophagy - animal	17/1180	164/7206	0.032888827003
ko04668	TNF signaling pathway	11/1180	120/7206	0.0335064443427
ko04933	AGE-RAGE signaling pathway in diabetic complications	13/1180	135/7206	0.0338370454242
ko00500	Starch and sucrose metabolism	1/1180	35/7206	0.0351115446515
ko05206	MicroRNAs in cancer	19/1180	177/7206	0.039535252004
ko00562	Inositol phosphate metabolism	22/1180	89/7206	0.0422520037597
ko05166	HTLV-I infection	35/1180	292/7206	0.0431050966323
ko03320	PPAR signaling pathway	5/1180	69/7206	0.047626574322
ko00230	Purine metabolism	42/1180	194/7206	0.0489948569718
ko05340	Primary immunodeficiency	1/1180	30/7206	0.0492380474122