ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	106/867	145/7206	3.74955128486e-67
ko04110	Cell cycle	68/867	145/7206	7.09850723878e-26
ko03013	RNA transport	73/867	166/7206	1.52984417486e-25
ko03030	DNA replication	31/867	38/7206	1.04563799125e-22
ko04111	Cell cycle - yeast	46/867	90/7206	9.07631430607e-20
ko05322	Systemic lupus erythematosus	61/867	151/7206	3.2351109558e-19
ko03008	Ribosome biogenesis in eukaryotes	41/867	79/7206	4.588306816e-18
ko03460	Fanconi anemia pathway	31/867	51/7206	1.35389079098e-16
ko03410	Base excision repair	25/867	38/7206	8.57049600363e-15
ko00240	Pyrimidine metabolism	44/867	110/7206	5.31950576253e-14
ko03420	Nucleotide excision repair	26/867	46/7206	4.50298699215e-13
ko03440	Homologous recombination	24/867	41/7206	1.26922508714e-12
ko04020	Calcium signaling pathway	2/867	265/7206	1.39985483832e-12
ko04113	Meiosis - yeast	32/867	70/7206	2.05062727562e-12
ko03430	Mismatch repair	17/867	22/7206	2.94240435177e-12
ko03022	Basal transcription factors	24/867	44/7206	1.03075167976e-11
ko03015	mRNA surveillance pathway	36/867	93/7206	3.39077811069e-11
ko04144	Endocytosis	8/867	342/7206	6.33358202428e-11
ko05034	Alcoholism	65/867	238/7206	7.66921801366e-11
ko05203	Viral carcinogenesis	72/867	277/7206	8.2846173806e-11
ko05010	Alzheimer's disease	1/867	202/7206	1.87849638154e-10
ko03020	RNA polymerase	18/867	29/7206	2.24259284056e-10
ko03018	RNA degradation	31/867	84/7206	3.16767950503e-09
ko04723	Retrograde endocannabinoid signaling	2/867	175/7206	9.39768700357e-08
ko04724	Glutamatergic synapse	1/867	152/7206	9.81852217523e-08
ko04060	Cytokine-cytokine receptor interaction	3/867	191/7206	1.04436995933e-07
ko04024	cAMP signaling pathway	9/867	279/7206	1.66970224651e-07
ko04921	Oxytocin signaling pathway	5/867	209/7206	6.98903538709e-07
ko04270	Vascular smooth muscle contraction	2/867	154/7206	1.00558400788e-06
ko05012	Parkinson's disease	2/867	155/7206	1.04138090624e-06
ko04022	cGMP-PKG signaling pathway	6/867	216/7206	1.23047766745e-06
ko03010	Ribosome	1/867	129/7206	1.75231696475e-06
ko04072	Phospholipase D signaling pathway	5/867	197/7206	2.04337884298e-06
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/867	182/7206	2.33981633138e-06
ko00190	Oxidative phosphorylation	1/867	127/7206	2.71575439134e-06
ko04151	PI3K-Akt signaling pathway	20/867	390/7206	2.88640439974e-06
ko04014	Ras signaling pathway	11/867	279/7206	3.12092158915e-06
ko04725	Cholinergic synapse	3/867	160/7206	3.43473875986e-06
ko04621	NOD-like receptor signaling pathway	3/867	157/7206	5.05357330222e-06
ko04713	Circadian entrainment	2/867	136/7206	7.17843097811e-06
ko04726	Serotonergic synapse	2/867	137/7206	7.23654165507e-06
ko04514	Cell adhesion molecules (CAMs)	2/867	130/7206	1.57894165258e-05
ko04261	Adrenergic signaling in cardiomyocytes	7/867	205/7206	1.70060590277e-05
ko04727	GABAergic synapse	1/867	110/7206	2.05314320395e-05
ko04062	Chemokine signaling pathway	7/867	201/7206	2.40182424942e-05
ko04530	Tight junction	9/867	228/7206	2.79232763373e-05
ko04510	Focal adhesion	10/867	240/7206	2.88970688287e-05
ko04668	TNF signaling pathway	2/867	120/7206	5.087397706e-05
ko05146	Amoebiasis	1/867	99/7206	6.79763720581e-05
ko00564	Glycerophospholipid metabolism	1/867	99/7206	6.79763720581e-05
ko04611	Platelet activation	5/867	163/7206	7.54116891587e-05
ko04911	Insulin secretion	2/867	117/7206	7.54428818315e-05
ko04371	Apelin signaling pathway	6/867	177/7206	8.75638536745e-05
ko04970	Salivary secretion	1/867	95/7206	0.000101917791494
ko04915	Estrogen signaling pathway	3/867	131/7206	0.000106252250079
ko04971	Gastric acid secretion	1/867	98/7206	0.000109132111189
ko05414	Dilated cardiomyopathy	2/867	112/7206	0.000109834629249
ko00230	Purine metabolism	42/867	194/7206	0.000117370396013
ko04728	Dopaminergic synapse	7/867	185/7206	0.000130131416762
ko05032	Morphine addiction	2/867	110/7206	0.000162241930395
ko04912	GnRH signaling pathway	3/867	122/7206	0.000216558510446
ko04920	Adipocytokine signaling pathway	1/867	89/7206	0.00022701507944
ko04010	MAPK signaling pathway	19/867	321/7206	0.000289996164464
ko05166	HTLV-I infection	56/867	292/7206	0.000311451955274
ko05152	Tuberculosis	8/867	187/7206	0.000358917775136
ko04380	Osteoclast differentiation	4/867	134/7206	0.000389054973504
ko04015	Rap1 signaling pathway	16/867	278/7206	0.00047494297399
ko04141	Protein processing in endoplasmic reticulum	8/867	184/7206	0.000496076131187
ko05410	Hypertrophic cardiomyopathy (HCM)	2/867	100/7206	0.000511456087993
ko04620	Toll-like receptor signaling pathway	2/867	100/7206	0.000511456087993
ko04540	Gap junction	4/867	128/7206	0.000535175379611
ko05142	Chagas disease (American trypanosomiasis)	4/867	130/7206	0.000545233176304
ko04070	Phosphatidylinositol signaling system	3/867	112/7206	0.00064825063954
ko04810	Regulation of actin cytoskeleton	15/867	264/7206	0.000676957277556
ko05168	Herpes simplex infection	38/867	182/7206	0.000702956510223
ko04721	Synaptic vesicle cycle	1/867	80/7206	0.00076399950155
ko05145	Toxoplasmosis	4/867	126/7206	0.000765826490543
ko04670	Leukocyte transendothelial migration	6/867	151/7206	0.000890721367107
ko05160	Hepatitis C	6/867	153/7206	0.000925749789827
ko04972	Pancreatic secretion	3/867	111/7206	0.000974020721586
ko05169	Epstein-Barr virus infection	41/867	206/7206	0.00100427396194
ko04750	Inflammatory mediator regulation of TRP channels	4/867	122/7206	0.00107760618219
ko04330	Notch signaling pathway	17/867	62/7206	0.00109684825888
ko05140	Leishmaniasis	1/867	75/7206	0.00111938881651
ko05134	Legionellosis	1/867	74/7206	0.00172774602727
ko04924	Renin secretion	2/867	86/7206	0.00228750149775
ko05133	Pertussis	2/867	87/7206	0.00233482837485
ko04662	B cell receptor signaling pathway	2/867	88/7206	0.00242069258692
ko03320	PPAR signaling pathway	1/867	69/7206	0.00246782611647
ko04152	AMPK signaling pathway	8/867	161/7206	0.00310675088559
ko04071	Sphingolipid signaling pathway	8/867	162/7206	0.00311989935743
ko04660	T cell receptor signaling pathway	5/867	124/7206	0.00316620902923
ko04931	Insulin resistance	6/867	137/7206	0.0032289262815
ko04550	Signaling pathways regulating pluripotency of stem cells	33/867	165/7206	0.00331642731494
ko04114	Oocyte meiosis	29/867	139/7206	0.00335300958191
ko04650	Natural killer cell mediated cytotoxicity	3/867	97/7206	0.0040130504829
ko04910	Insulin signaling pathway	9/867	172/7206	0.0040637293463
ko05202	Transcriptional misregulation in cancer	36/867	188/7206	0.00422707542014
ko04630	Jak-STAT signaling pathway	6/867	132/7206	0.00440558890295
ko05231	Choline metabolism in cancer	6/867	134/7206	0.00445034850142
ko04933	AGE-RAGE signaling pathway in diabetic complications	6/867	135/7206	0.00453497202213
ko04730	Long-term depression	2/867	78/7206	0.00477727176681
ko04740	Olfactory transduction	2/867	80/7206	0.00487227255157
ko04120	Ubiquitin mediated proteolysis	28/867	138/7206	0.00504838022043
ko00561	Glycerolipid metabolism	1/867	63/7206	0.00547103645852
ko05031	Amphetamine addiction	3/867	91/7206	0.00549228592132
ko04360	Axon guidance	15/867	233/7206	0.00555703636173
ko04640	Hematopoietic cell lineage	1/867	64/7206	0.00563771541386
ko04925	Aldosterone synthesis and secretion	4/867	105/7206	0.0059325376257
ko04659	Th17 cell differentiation	4/867	106/7206	0.00604358726031
ko04923	Regulation of lipolysis in adipocytes	2/867	77/7206	0.0071128041608
ko05217	Basal cell carcinoma	16/867	68/7206	0.00741699493327
ko04146	Peroxisome	3/867	89/7206	0.00785615562442
ko00562	Inositol phosphate metabolism	3/867	89/7206	0.00785615562442
ko01212	Fatty acid metabolism	1/867	60/7206	0.00815918398701
ko01200	Carbon metabolism	6/867	128/7206	0.00843228877943
ko04722	Neurotrophin signaling pathway	9/867	160/7206	0.00939621916462
ko05030	Cocaine addiction	2/867	73/7206	0.0100861652139
ko00010	Glycolysis / Gluconeogenesis	2/867	74/7206	0.010379300997
ko05132	Salmonella infection	4/867	98/7206	0.0114761077087
ko05321	Inflammatory bowel disease (IBD)	1/867	56/7206	0.0118790121642
ko04914	Progesterone-mediated oocyte maturation	21/867	104/7206	0.0145460010334
ko04138	Autophagy - yeast	3/867	81/7206	0.0154241314671
ko04930	Type II diabetes mellitus	1/867	54/7206	0.0181742513084
ko05120	Epithelial cell signaling in Helicobacter pylori infection	4/867	92/7206	0.0222747382183
ko04340	Hedgehog signaling pathway	13/867	58/7206	0.0234165405533
ko05167	Kaposi's sarcoma-associated herpesvirus infection	13/867	191/7206	0.0235697882498
ko04066	HIF-1 signaling pathway	7/867	123/7206	0.025103251486
ko00380	Tryptophan metabolism	1/867	50/7206	0.0261777580035
ko03450	Non-homologous end-joining	5/867	15/7206	0.0266308477543
ko04622	RIG-I-like receptor signaling pathway	2/867	62/7206	0.0292527613812
ko04918	Thyroid hormone synthesis	4/867	86/7206	0.0297824807777
ko04657	IL-17 signaling pathway	4/867	87/7206	0.0299059715206
ko04012	ErbB signaling pathway	6/867	109/7206	0.036345950364
ko04310	Wnt signaling pathway	31/867	181/7206	0.0371931482567
ko04145	Phagosome	11/867	162/7206	0.0373281987651
ko00620	Pyruvate metabolism	1/867	46/7206	0.0378768248086
ko04064	NF-kappa B signaling pathway	5/867	96/7206	0.0387503619596
ko04215	Apoptosis - multiple species	1/867	47/7206	0.0388596853152
ko04922	Glucagon signaling pathway	8/867	128/7206	0.0396772341859
ko04137	Mitophagy - animal	4/867	82/7206	0.0407270010697
ko04962	Vasopressin-regulated water reabsorption	2/867	58/7206	0.0413960478303
ko04712	Circadian rhythm - plant	3/867	7/7206	0.0418455252159
ko04142	Lysosome	10/867	151/7206	0.0419828662077
ko04218	Cellular senescence	30/867	177/7206	0.0465831132508
ko01521	EGFR tyrosine kinase inhibitor resistance	6/867	106/7206	0.0486261689528