ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	57/638	152/7206	1.01353216744e-22
ko05033	Nicotine addiction	34/638	56/7206	2.30320612284e-22
ko04727	GABAergic synapse	41/638	110/7206	1.60310609482e-16
ko05032	Morphine addiction	40/638	110/7206	1.02783500193e-15
ko04080	Neuroactive ligand-receptor interaction	89/638	423/7206	1.55656621743e-15
ko04728	Dopaminergic synapse	53/638	185/7206	2.63825329359e-15
ko04723	Retrograde endocannabinoid signaling	49/638	175/7206	8.31787597897e-14
ko04713	Circadian entrainment	40/638	136/7206	3.10146992992e-12
ko04024	cAMP signaling pathway	62/638	279/7206	3.61752620569e-12
ko04360	Axon guidance	55/638	233/7206	5.18602378623e-12
ko04725	Cholinergic synapse	43/638	160/7206	1.32528876786e-11
ko04721	Synaptic vesicle cycle	28/638	80/7206	6.47046367303e-11
ko04911	Insulin secretion	33/638	117/7206	8.69396699426e-10
ko04726	Serotonergic synapse	36/638	137/7206	1.26844441006e-09
ko04514	Cell adhesion molecules (CAMs)	31/638	130/7206	2.04702489598e-07
ko04261	Adrenergic signaling in cardiomyocytes	42/638	205/7206	2.41311571893e-07
ko05030	Cocaine addiction	20/638	73/7206	3.12659378518e-06
ko04921	Oxytocin signaling pathway	39/638	209/7206	5.58535159416e-06
ko05031	Amphetamine addiction	22/638	91/7206	9.56051193786e-06
ko04720	Long-term potentiation	23/638	99/7206	1.22266067369e-05
ko04970	Salivary secretion	22/638	95/7206	1.99037954746e-05
ko03040	Spliceosome	1/638	145/7206	4.0571119633e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	18/638	74/7206	5.62366567491e-05
ko05203	Viral carcinogenesis	8/638	277/7206	8.66870890799e-05
ko04020	Calcium signaling pathway	43/638	265/7206	9.09315191427e-05
ko04972	Pancreatic secretion	23/638	111/7206	0.000115895625188
ko04730	Long-term depression	18/638	78/7206	0.000117430097011
ko04010	MAPK signaling pathway	49/638	321/7206	0.000118399754741
ko03013	RNA transport	3/638	166/7206	0.000265247917041
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/638	59/7206	0.000488461956032
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/638	14/7206	0.000760025111712
ko00240	Pyrimidine metabolism	1/638	110/7206	0.000960631866502
ko04071	Sphingolipid signaling pathway	27/638	162/7206	0.00112474655353
ko05164	Influenza A	4/638	167/7206	0.00129125767657
ko04072	Phospholipase D signaling pathway	31/638	197/7206	0.00134476388966
ko05168	Herpes simplex infection	5/638	182/7206	0.00137267055821
ko04022	cGMP-PKG signaling pathway	33/638	216/7206	0.00209035240353
ko04070	Phosphatidylinositol signaling system	20/638	112/7206	0.00210173336364
ko04742	Taste transduction	13/638	61/7206	0.00221340799422
ko04014	Ras signaling pathway	40/638	279/7206	0.00239135476502
ko04960	Aldosterone-regulated sodium reabsorption	10/638	41/7206	0.00246561303941
ko04964	Proximal tubule bicarbonate reclamation	8/638	29/7206	0.00289397767512
ko05322	Systemic lupus erythematosus	4/638	151/7206	0.00345922376928
ko05205	Proteoglycans in cancer	12/638	271/7206	0.00626092863034
ko04260	Cardiac muscle contraction	17/638	98/7206	0.0062692873851
ko04971	Gastric acid secretion	17/638	98/7206	0.0062692873851
ko04217	Necroptosis	6/638	178/7206	0.00690793089937
ko04610	Complement and coagulation cascades	1/638	79/7206	0.00902819080089
ko04120	Ubiquitin mediated proteolysis	4/638	138/7206	0.00929441026723
ko04973	Carbohydrate digestion and absorption	9/638	42/7206	0.00985847047113
ko04918	Thyroid hormone synthesis	15/638	86/7206	0.0109987254189
ko04744	Phototransduction	8/638	36/7206	0.0117588552291
ko04925	Aldosterone synthesis and secretion	17/638	105/7206	0.0138494563388
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	14/638	79/7206	0.0143210148386
ko04015	Rap1 signaling pathway	36/638	278/7206	0.0176982019492
ko05169	Epstein-Barr virus infection	9/638	206/7206	0.0177373865797
ko04060	Cytokine-cytokine receptor interaction	8/638	191/7206	0.0193431987183
ko04621	NOD-like receptor signaling pathway	6/638	157/7206	0.0221198041364
ko04141	Protein processing in endoplasmic reticulum	8/638	184/7206	0.025169605605
ko04540	Gap junction	19/638	128/7206	0.0260479088989
ko04915	Estrogen signaling pathway	19/638	131/7206	0.0287270817989
ko05230	Central carbon metabolism in cancer	13/638	81/7206	0.0294456840504
ko04962	Vasopressin-regulated water reabsorption	10/638	58/7206	0.0339877689003
ko04391	Hippo signaling pathway - fly	14/638	90/7206	0.0369242852685
ko02024	Quorum sensing	4/638	15/7206	0.0377419822011
ko04110	Cell cycle	6/638	145/7206	0.0388161364117
ko04137	Mitophagy - animal	2/638	82/7206	0.046762185406