ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	168/924	423/7206	1.73595950068e-47
ko04724	Glutamatergic synapse	84/924	152/7206	1.31301896753e-36
ko05033	Nicotine addiction	46/924	56/7206	3.39558770899e-32
ko04727	GABAergic synapse	60/924	110/7206	5.97713784529e-26
ko05032	Morphine addiction	60/924	110/7206	5.97713784529e-26
ko04713	Circadian entrainment	66/924	136/7206	1.34115725948e-24
ko04728	Dopaminergic synapse	77/924	185/7206	3.29590667809e-23
ko04723	Retrograde endocannabinoid signaling	72/924	175/7206	2.10779373337e-21
ko04721	Synaptic vesicle cycle	44/924	80/7206	1.63103060624e-19
ko04725	Cholinergic synapse	65/924	160/7206	4.53856190565e-19
ko04024	cAMP signaling pathway	88/924	279/7206	6.71205278265e-17
ko04911	Insulin secretion	51/924	117/7206	9.59889769194e-17
ko04742	Taste transduction	34/924	61/7206	1.3487860008e-15
ko04020	Calcium signaling pathway	80/924	265/7206	2.86729604146e-14
ko04726	Serotonergic synapse	51/924	137/7206	2.09607105494e-13
ko05031	Amphetamine addiction	38/924	91/7206	4.3211742369e-12
ko04720	Long-term potentiation	39/924	99/7206	1.9780675151e-11
ko04921	Oxytocin signaling pathway	63/924	209/7206	2.5000319652e-11
ko04740	Olfactory transduction	34/924	80/7206	3.27636382061e-11
ko04261	Adrenergic signaling in cardiomyocytes	60/924	205/7206	2.18974014476e-10
ko04970	Salivary secretion	36/924	95/7206	4.3124883314e-10
ko04744	Phototransduction	20/924	36/7206	1.14678090208e-09
ko05030	Cocaine addiction	29/924	73/7206	6.16328373017e-09
ko04925	Aldosterone synthesis and secretion	35/924	105/7206	3.69618118864e-08
ko03040	Spliceosome	1/924	145/7206	9.45977909797e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	27/924	74/7206	1.67423038694e-07
ko04971	Gastric acid secretion	31/924	98/7206	8.26195429104e-07
ko04514	Cell adhesion molecules (CAMs)	37/924	130/7206	1.6844940137e-06
ko04120	Ubiquitin mediated proteolysis	2/924	138/7206	2.02524075968e-06
ko04010	MAPK signaling pathway	71/924	321/7206	2.11334198128e-06
ko05203	Viral carcinogenesis	12/924	277/7206	2.17159907107e-06
ko05168	Herpes simplex infection	5/924	182/7206	2.72621322586e-06
ko04022	cGMP-PKG signaling pathway	52/924	216/7206	4.00876358673e-06
ko04972	Pancreatic secretion	32/924	111/7206	5.46518334721e-06
ko04360	Axon guidance	54/924	233/7206	9.13412836652e-06
ko03013	RNA transport	5/924	166/7206	1.69409192686e-05
ko04060	Cytokine-cytokine receptor interaction	7/924	191/7206	2.29037630758e-05
ko04540	Gap junction	34/924	128/7206	2.29591161184e-05
ko04621	NOD-like receptor signaling pathway	5/924	157/7206	5.04221631615e-05
ko05164	Influenza A	6/924	167/7206	5.67269307721e-05
ko04260	Cardiac muscle contraction	27/924	98/7206	8.84251182392e-05
ko04730	Long-term depression	23/924	78/7206	9.55292916947e-05
ko05322	Systemic lupus erythematosus	5/924	151/7206	0.000103923699913
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/924	79/7206	0.000110870236391
ko04745	Phototransduction - fly	14/924	38/7206	0.000144024873253
ko04966	Collecting duct acid secretion	11/924	26/7206	0.000178947970396
ko04072	Phospholipase D signaling pathway	44/924	197/7206	0.000198570101336
ko04915	Estrogen signaling pathway	32/924	131/7206	0.000284108326622
ko04924	Renin secretion	23/924	86/7206	0.000466804931739
ko04141	Protein processing in endoplasmic reticulum	9/924	184/7206	0.000470523859952
ko04612	Antigen processing and presentation	1/924	77/7206	0.000479404742256
ko05414	Dilated cardiomyopathy	28/924	112/7206	0.000479887631916
ko04014	Ras signaling pathway	56/924	279/7206	0.000481539632821
ko04610	Complement and coagulation cascades	1/924	79/7206	0.000500086089042
ko03008	Ribosome biogenesis in eukaryotes	1/924	79/7206	0.000500086089042
ko05162	Measles	4/924	120/7206	0.000509896830882
ko04626	Plant-pathogen interaction	8/924	18/7206	0.000946067104068
ko05205	Proteoglycans in cancer	18/924	271/7206	0.00112678643583
ko04064	NF-kappa B signaling pathway	3/924	96/7206	0.00183427139503
ko05110	Vibrio cholerae infection	17/924	63/7206	0.00204856698825
ko04750	Inflammatory mediator regulation of TRP channels	28/924	122/7206	0.00229631195097
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/924	59/7206	0.00268720088724
ko04976	Bile secretion	20/924	80/7206	0.00347543150418
ko04371	Apelin signaling pathway	36/924	177/7206	0.00418929944138
ko05140	Leishmaniasis	2/924	75/7206	0.00468733627473
ko04110	Cell cycle	8/924	145/7206	0.00544605465764
ko00240	Pyrimidine metabolism	5/924	110/7206	0.00585866910869
ko04217	Necroptosis	11/924	178/7206	0.00603774362328
ko04070	Phosphatidylinositol signaling system	25/924	112/7206	0.00609457636717
ko04140	Autophagy - animal	10/924	164/7206	0.00639868066039
ko04214	Apoptosis - fly	2/924	72/7206	0.00682059866343
ko03018	RNA degradation	3/924	84/7206	0.00767948618322
ko00480	Glutathione metabolism	1/924	55/7206	0.00773476257832
ko05161	Hepatitis B	11/924	173/7206	0.00779079774258
ko05169	Epstein-Barr virus infection	14/924	206/7206	0.00780419420052
ko04630	Jak-STAT signaling pathway	7/924	132/7206	0.0079138137725
ko04964	Proximal tubule bicarbonate reclamation	9/924	29/7206	0.00825160132462
ko04912	GnRH signaling pathway	26/924	122/7206	0.00869704555502
ko04923	Regulation of lipolysis in adipocytes	18/924	77/7206	0.00932668328634
ko04932	Non-alcoholic fatty liver disease (NAFLD)	12/924	182/7206	0.00935770560636
ko04510	Focal adhesion	18/924	240/7206	0.0104103193606
ko04640	Hematopoietic cell lineage	2/924	64/7206	0.0138396939819
ko04918	Thyroid hormone synthesis	19/924	86/7206	0.014332569641
ko05215	Prostate cancer	6/924	111/7206	0.0145696881469
ko01524	Platinum drug resistance	3/924	76/7206	0.0150045588892
ko05166	HTLV-I infection	24/924	292/7206	0.0155174918656
ko04146	Peroxisome	4/924	89/7206	0.0155312371905
ko05219	Bladder cancer	1/924	48/7206	0.0169415623556
ko05034	Alcoholism	43/924	238/7206	0.017663995138
ko00330	Arginine and proline metabolism	2/924	61/7206	0.019886415165
ko04330	Notch signaling pathway	2/924	62/7206	0.0201747040925
ko00561	Glycerolipid metabolism	2/924	63/7206	0.0207632286164
ko00310	Lysine degradation	3/924	73/7206	0.0211114256452
ko04930	Type II diabetes mellitus	13/924	54/7206	0.021999608346
ko05410	Hypertrophic cardiomyopathy (HCM)	21/924	100/7206	0.0223458794081
ko01200	Carbon metabolism	8/924	128/7206	0.0226786156274
ko04210	Apoptosis	13/924	180/7206	0.0232055288657
ko05144	Malaria	1/924	45/7206	0.0249309632543
ko00071	Fatty acid degradation	1/924	45/7206	0.0249309632543
ko03420	Nucleotide excision repair	1/924	46/7206	0.0250349092703
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/924	14/7206	0.0253636257111
ko04015	Rap1 signaling pathway	48/924	278/7206	0.0278945795007
ko04270	Vascular smooth muscle contraction	29/924	154/7206	0.0282763080047
ko04916	Melanogenesis	27/924	142/7206	0.0308680435646
ko04062	Chemokine signaling pathway	36/924	201/7206	0.0323631136435
ko04142	Lysosome	11/924	151/7206	0.0365953183579
ko05418	Fluid shear stress and atherosclerosis	13/924	173/7206	0.0373504572891
ko05222	Small cell lung cancer	5/924	89/7206	0.0377689290966
ko03022	Basal transcription factors	1/924	44/7206	0.0378924004737
ko00280	Valine, leucine and isoleucine degradation	2/924	54/7206	0.0404774882951
ko04114	Oocyte meiosis	26/924	139/7206	0.0405062817508
ko00564	Glycerophospholipid metabolism	6/924	99/7206	0.0473994342646
ko05016	Huntington's disease	18/924	215/7206	0.0487265141405