ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	128/720	423/7206	1.37614501991e-33
ko04724	Glutamatergic synapse	69/720	152/7206	3.38728345651e-30
ko05033	Nicotine addiction	40/720	56/7206	3.14377607377e-28
ko04728	Dopaminergic synapse	63/720	185/7206	1.38429631438e-19
ko05032	Morphine addiction	47/720	110/7206	1.67133253614e-19
ko04727	GABAergic synapse	46/720	110/7206	1.1769044686e-18
ko04723	Retrograde endocannabinoid signaling	59/720	175/7206	3.67184952752e-18
ko04713	Circadian entrainment	51/720	136/7206	4.24860169253e-18
ko04024	cAMP signaling pathway	73/720	279/7206	2.3873201136e-15
ko04725	Cholinergic synapse	51/720	160/7206	1.03942635387e-14
ko04721	Synaptic vesicle cycle	34/720	80/7206	2.3526053934e-14
ko04911	Insulin secretion	38/720	117/7206	1.51323522123e-11
ko04726	Serotonergic synapse	41/720	137/7206	4.45606176744e-11
ko05031	Amphetamine addiction	32/720	91/7206	6.02984434634e-11
ko04261	Adrenergic signaling in cardiomyocytes	52/720	205/7206	1.08441542456e-10
ko04921	Oxytocin signaling pathway	51/720	209/7206	9.31818066166e-10
ko04020	Calcium signaling pathway	58/720	265/7206	6.54564312717e-09
ko04720	Long-term potentiation	30/720	99/7206	1.3632875291e-08
ko05030	Cocaine addiction	25/720	73/7206	1.43702770464e-08
ko04742	Taste transduction	22/720	61/7206	3.63935001473e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	24/720	74/7206	9.24667545806e-08
ko04010	MAPK signaling pathway	63/720	321/7206	9.67043922624e-08
ko04970	Salivary secretion	27/720	95/7206	3.13654491519e-07
ko04514	Cell adhesion molecules (CAMs)	32/720	130/7206	9.39539688346e-07
ko04730	Long-term depression	22/720	78/7206	4.47603638558e-06
ko03040	Spliceosome	1/720	145/7206	7.6202279617e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/720	79/7206	2.00981230062e-05
ko04260	Cardiac muscle contraction	24/720	98/7206	2.35433221996e-05
ko05164	Influenza A	3/720	167/7206	3.95793112261e-05
ko04925	Aldosterone synthesis and secretion	25/720	105/7206	4.13848060878e-05
ko04022	cGMP-PKG signaling pathway	41/720	216/7206	4.32483504866e-05
ko05203	Viral carcinogenesis	10/720	277/7206	8.6582975692e-05
ko04971	Gastric acid secretion	23/720	98/7206	0.000101826089183
ko04744	Phototransduction	12/720	36/7206	0.00011768827502
ko04060	Cytokine-cytokine receptor interaction	5/720	191/7206	0.000122544215843
ko05322	Systemic lupus erythematosus	3/720	151/7206	0.000172164250761
ko05168	Herpes simplex infection	5/720	182/7206	0.000243269215894
ko04740	Olfactory transduction	19/720	80/7206	0.000252478978825
ko04972	Pancreatic secretion	24/720	111/7206	0.000299901070566
ko04360	Axon guidance	41/720	233/7206	0.000318652362832
ko04120	Ubiquitin mediated proteolysis	3/720	138/7206	0.000774272039783
ko03013	RNA transport	5/720	166/7206	0.000936798667262
ko00240	Pyrimidine metabolism	2/720	110/7206	0.00120711180195
ko04072	Phospholipase D signaling pathway	34/720	197/7206	0.00152323926839
ko04621	NOD-like receptor signaling pathway	5/720	157/7206	0.00180860667231
ko04014	Ras signaling pathway	44/720	279/7206	0.00208970919306
ko04540	Gap junction	24/720	128/7206	0.00246328265552
ko05205	Proteoglycans in cancer	13/720	271/7206	0.00255499147043
ko04141	Protein processing in endoplasmic reticulum	7/720	184/7206	0.00257474605314
ko05162	Measles	3/720	120/7206	0.00304889343352
ko04745	Phototransduction - fly	10/720	38/7206	0.00328632896848
ko05166	HTLV-I infection	15/720	292/7206	0.00363828682343
ko03008	Ribosome biogenesis in eukaryotes	1/720	79/7206	0.00401947416573
ko05169	Epstein-Barr virus infection	9/720	206/7206	0.00435581243463
ko04964	Proximal tubule bicarbonate reclamation	8/720	29/7206	0.00610659889434
ko04612	Antigen processing and presentation	1/720	77/7206	0.0061583972581
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/720	59/7206	0.00663479555204
ko04915	Estrogen signaling pathway	23/720	131/7206	0.00729402912213
ko05414	Dilated cardiomyopathy	20/720	112/7206	0.00992535818056
ko04146	Peroxisome	2/720	89/7206	0.0111785747587
ko04966	Collecting duct acid secretion	7/720	26/7206	0.0116665656046
ko04350	TGF-beta signaling pathway	3/720	103/7206	0.0119342766716
ko04630	Jak-STAT signaling pathway	5/720	132/7206	0.0122078487643
ko04110	Cell cycle	6/720	145/7206	0.0163049704297
ko04924	Renin secretion	16/720	86/7206	0.0165152533064
ko04932	Non-alcoholic fatty liver disease (NAFLD)	9/720	182/7206	0.0172281022823
ko04640	Hematopoietic cell lineage	1/720	64/7206	0.0189403196413
ko04930	Type II diabetes mellitus	11/720	54/7206	0.0194294820589
ko05034	Alcoholism	35/720	238/7206	0.0202289271725
ko04750	Inflammatory mediator regulation of TRP channels	20/720	122/7206	0.0222579837652
ko05010	Alzheimer's disease	30/720	202/7206	0.0236120499908
ko04064	NF-kappa B signaling pathway	3/720	96/7206	0.0238193467438
ko04071	Sphingolipid signaling pathway	25/720	162/7206	0.0241013840431
ko04070	Phosphatidylinositol signaling system	19/720	112/7206	0.0242828457919
ko05410	Hypertrophic cardiomyopathy (HCM)	17/720	100/7206	0.0272793971408
ko04626	Plant-pathogen interaction	5/720	18/7206	0.027929706933
ko00330	Arginine and proline metabolism	1/720	61/7206	0.028421508241
ko05110	Vibrio cholerae infection	12/720	63/7206	0.0307489174494
ko05140	Leishmaniasis	2/720	75/7206	0.0311131470409
ko00480	Glutathione metabolism	1/720	55/7206	0.0397702353314
ko04371	Apelin signaling pathway	26/720	177/7206	0.0416189376895
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/720	14/7206	0.0438521138574
ko04214	Apoptosis - fly	2/720	72/7206	0.044848031038
ko04550	Signaling pathways regulating pluripotency of stem cells	9/720	165/7206	0.0484875924262