ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	148/880	423/7206	1.26086667252e-36
ko04724	Glutamatergic synapse	73/880	152/7206	3.95210874769e-28
ko05033	Nicotine addiction	41/880	56/7206	4.13633598247e-26
ko05032	Morphine addiction	55/880	110/7206	1.69041668378e-22
ko04713	Circadian entrainment	58/880	136/7206	2.27945192948e-19
ko04727	GABAergic synapse	51/880	110/7206	4.27506476438e-19
ko04728	Dopaminergic synapse	69/880	185/7206	5.86256506123e-19
ko04721	Synaptic vesicle cycle	42/880	80/7206	1.77516406157e-18
ko04723	Retrograde endocannabinoid signaling	64/880	175/7206	3.71618746498e-17
ko04725	Cholinergic synapse	60/880	160/7206	9.45411946318e-17
ko04726	Serotonergic synapse	49/880	137/7206	5.5849046721e-13
ko04911	Insulin secretion	43/880	117/7206	5.31738472547e-12
ko04024	cAMP signaling pathway	74/880	279/7206	3.36557481722e-11
ko04020	Calcium signaling pathway	70/880	265/7206	1.56844969038e-10
ko04921	Oxytocin signaling pathway	59/880	209/7206	2.29033101298e-10
ko05031	Amphetamine addiction	32/880	91/7206	1.02145015954e-08
ko04742	Taste transduction	25/880	61/7206	1.21509824294e-08
ko03040	Spliceosome	1/880	145/7206	2.28202073171e-07
ko04261	Adrenergic signaling in cardiomyocytes	51/880	205/7206	3.74694056444e-07
ko04720	Long-term potentiation	30/880	99/7206	1.20636163192e-06
ko04970	Salivary secretion	29/880	95/7206	1.53456226561e-06
ko05030	Cocaine addiction	24/880	73/7206	2.86521096114e-06
ko04360	Axon guidance	53/880	233/7206	5.3868891938e-06
ko04010	MAPK signaling pathway	67/880	321/7206	6.94219449982e-06
ko05322	Systemic lupus erythematosus	3/880	151/7206	7.25757820106e-06
ko04514	Cell adhesion molecules (CAMs)	34/880	130/7206	1.01710043385e-05
ko03013	RNA transport	4/880	166/7206	1.02683209801e-05
ko04730	Long-term depression	24/880	78/7206	1.04652330908e-05
ko04971	Gastric acid secretion	28/880	98/7206	1.22391478684e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	23/880	74/7206	1.32506582203e-05
ko04925	Aldosterone synthesis and secretion	29/880	105/7206	1.48451469577e-05
ko04966	Collecting duct acid secretion	12/880	26/7206	1.91853010894e-05
ko04120	Ubiquitin mediated proteolysis	3/880	138/7206	3.32173725862e-05
ko04972	Pancreatic secretion	29/880	111/7206	5.10265841782e-05
ko04540	Gap junction	32/880	128/7206	5.45778622966e-05
ko04710	Circadian rhythm	15/880	43/7206	9.78668079916e-05
ko05110	Vibrio cholerae infection	19/880	63/7206	0.000116506852117
ko05164	Influenza A	6/880	167/7206	0.000168668283698
ko05162	Measles	3/880	120/7206	0.000214157581497
ko04022	cGMP-PKG signaling pathway	44/880	216/7206	0.00046566919575
ko05203	Viral carcinogenesis	16/880	277/7206	0.00048167600859
ko05168	Herpes simplex infection	8/880	182/7206	0.000497317756115
ko04750	Inflammatory mediator regulation of TRP channels	28/880	122/7206	0.000722978733038
ko04014	Ras signaling pathway	53/880	279/7206	0.00100829401708
ko04964	Proximal tubule bicarbonate reclamation	10/880	29/7206	0.00157955149811
ko04060	Cytokine-cytokine receptor interaction	10/880	191/7206	0.00158004241166
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/880	59/7206	0.00187563820443
ko04141	Protein processing in endoplasmic reticulum	10/880	184/7206	0.00282176082207
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/880	79/7206	0.00290103565928
ko04976	Bile secretion	19/880	80/7206	0.00327246919172
ko04621	NOD-like receptor signaling pathway	8/880	157/7206	0.00421505734533
ko04260	Cardiac muscle contraction	22/880	98/7206	0.00444630859469
ko04745	Phototransduction - fly	11/880	38/7206	0.00448680746619
ko04612	Antigen processing and presentation	2/880	77/7206	0.004735965908
ko04930	Type II diabetes mellitus	14/880	54/7206	0.00521908596704
ko00330	Arginine and proline metabolism	1/880	61/7206	0.00536364904702
ko04915	Estrogen signaling pathway	27/880	131/7206	0.00641523344468
ko04072	Phospholipase D signaling pathway	37/880	197/7206	0.00763831082534
ko04146	Peroxisome	3/880	89/7206	0.00805478468254
ko04740	Olfactory transduction	18/880	80/7206	0.00892504541822
ko04110	Cell cycle	8/880	145/7206	0.00995949359259
ko04071	Sphingolipid signaling pathway	31/880	162/7206	0.0102568760587
ko04924	Renin secretion	19/880	86/7206	0.0115247580032
ko00280	Valine, leucine and isoleucine degradation	1/880	54/7206	0.0117177811912
ko05414	Dilated cardiomyopathy	23/880	112/7206	0.0123234658709
ko04070	Phosphatidylinositol signaling system	23/880	112/7206	0.0123234658709
ko05169	Epstein-Barr virus infection	14/880	206/7206	0.01290443546
ko04960	Aldosterone-regulated sodium reabsorption	11/880	41/7206	0.013089901522
ko04711	Circadian rhythm - fly	5/880	13/7206	0.0148834973818
ko04626	Plant-pathogen interaction	6/880	18/7206	0.0165409558038
ko04011	MAPK signaling pathway - yeast	1/880	53/7206	0.0179256938976
ko04640	Hematopoietic cell lineage	2/880	64/7206	0.0202833679121
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/880	14/7206	0.0208708405468
ko05120	Epithelial cell signaling in Helicobacter pylori infection	19/880	92/7206	0.023004632731
ko00260	Glycine, serine and threonine metabolism	1/880	48/7206	0.0254377751135
ko05140	Leishmaniasis	3/880	75/7206	0.0309951579622
ko04810	Regulation of actin cytoskeleton	21/880	264/7206	0.0344680833788
ko04744	Phototransduction	9/880	36/7206	0.0348874873707
ko04371	Apelin signaling pathway	31/880	177/7206	0.035762168712
ko04916	Melanogenesis	26/880	142/7206	0.036954348136
ko05205	Proteoglycans in cancer	22/880	271/7206	0.0370046524417
ko03022	Basal transcription factors	1/880	44/7206	0.0372728037473
ko03420	Nucleotide excision repair	1/880	46/7206	0.0383043009245
ko04510	Focal adhesion	19/880	240/7206	0.0441112746846
ko04918	Thyroid hormone synthesis	17/880	86/7206	0.0444355009386
ko05410	Hypertrophic cardiomyopathy (HCM)	19/880	100/7206	0.0446266744672
ko04217	Necroptosis	13/880	178/7206	0.0477370456698
ko04662	B cell receptor signaling pathway	17/880	88/7206	0.0484041922747