ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04380	Osteoclast differentiation	50/596	134/7206	3.02153457932e-21
ko04060	Cytokine-cytokine receptor interaction	60/596	191/7206	7.07894480714e-21
ko04064	NF-kappa B signaling pathway	36/596	96/7206	1.10463731449e-15
ko05164	Influenza A	47/596	167/7206	1.69052414847e-14
ko04621	NOD-like receptor signaling pathway	45/596	157/7206	3.0118713407e-14
ko04659	Th17 cell differentiation	35/596	106/7206	2.39045177119e-13
ko05140	Leishmaniasis	28/596	75/7206	2.03681512405e-12
ko05168	Herpes simplex infection	45/596	182/7206	9.25500491963e-12
ko04650	Natural killer cell mediated cytotoxicity	31/596	97/7206	1.51973397038e-11
ko05321	Inflammatory bowel disease (IBD)	23/596	56/7206	1.96589065166e-11
ko04660	T cell receptor signaling pathway	34/596	124/7206	1.76551796923e-10
ko04620	Toll-like receptor signaling pathway	30/596	100/7206	1.91164358482e-10
ko04217	Necroptosis	42/596	178/7206	2.31574419132e-10
ko04668	TNF signaling pathway	33/596	120/7206	3.02769408006e-10
ko05162	Measles	33/596	120/7206	3.02769408006e-10
ko04658	Th1 and Th2 cell differentiation	29/596	96/7206	3.21159407495e-10
ko04672	Intestinal immune network for IgA production	17/596	37/7206	1.05162179417e-09
ko05323	Rheumatoid arthritis	27/596	89/7206	1.19246537972e-09
ko05340	Primary immunodeficiency	15/596	30/7206	2.34838473633e-09
ko05145	Toxoplasmosis	32/596	126/7206	4.98779180039e-09
ko05150	Staphylococcus aureus infection	16/596	36/7206	6.01136541851e-09
ko05152	Tuberculosis	40/596	187/7206	1.32213069652e-08
ko04630	Jak-STAT signaling pathway	32/596	132/7206	1.69939072766e-08
ko04640	Hematopoietic cell lineage	21/596	64/7206	1.81232511035e-08
ko04662	B cell receptor signaling pathway	25/596	88/7206	2.18736943933e-08
ko05161	Hepatitis B	37/596	173/7206	4.72513585964e-08
ko04610	Complement and coagulation cascades	23/596	79/7206	4.86439765169e-08
ko05330	Allograft rejection	12/596	24/7206	9.84381911825e-08
ko05320	Autoimmune thyroid disease	13/596	29/7206	1.46180980247e-07
ko05332	Graft-versus-host disease	10/596	18/7206	3.30853763058e-07
ko05133	Pertussis	23/596	87/7206	3.40499239993e-07
ko05167	Kaposi's sarcoma-associated herpesvirus infection	37/596	191/7206	7.23387173388e-07
ko00120	Primary bile acid biosynthesis	10/596	20/7206	1.19868870143e-06
ko05144	Malaria	15/596	45/7206	1.61171218609e-06
ko05142	Chagas disease (American trypanosomiasis)	28/596	130/7206	1.79877857595e-06
ko04622	RIG-I-like receptor signaling pathway	17/596	62/7206	6.8395640582e-06
ko04612	Antigen processing and presentation	19/596	77/7206	1.07559811948e-05
ko04210	Apoptosis	33/596	180/7206	1.19320832882e-05
ko04623	Cytosolic DNA-sensing pathway	13/596	41/7206	1.49469528266e-05
ko04933	AGE-RAGE signaling pathway in diabetic complications	27/596	135/7206	1.967333532e-05
ko03013	RNA transport	1/596	166/7206	2.00871774971e-05
ko05310	Asthma	8/596	17/7206	2.59318371786e-05
ko04940	Type I diabetes mellitus	11/596	32/7206	2.90973398074e-05
ko04062	Chemokine signaling pathway	34/596	201/7206	4.4402165601e-05
ko04657	IL-17 signaling pathway	19/596	87/7206	6.74177382811e-05
ko05034	Alcoholism	5/596	238/7206	9.88937669678e-05
ko05418	Fluid shear stress and atherosclerosis	29/596	173/7206	0.000211702182087
ko04723	Retrograde endocannabinoid signaling	3/596	175/7206	0.000402278406598
ko04611	Platelet activation	27/596	163/7206	0.000434125589788
ko05160	Hepatitis C	26/596	153/7206	0.000477115170927
ko04728	Dopaminergic synapse	4/596	185/7206	0.000968029720976
ko05032	Morphine addiction	1/596	110/7206	0.00137024261651
ko04724	Glutamatergic synapse	3/596	152/7206	0.00160887457165
ko04666	Fc gamma R-mediated phagocytosis	20/596	122/7206	0.00254443737847
ko04080	Neuroactive ligand-receptor interaction	19/596	423/7206	0.00254993541654
ko00982	Drug metabolism - cytochrome P450	9/596	37/7206	0.00257933500237
ko00590	Arachidonic acid metabolism	11/596	52/7206	0.00297239697703
ko04916	Melanogenesis	3/596	142/7206	0.00321733658588
ko05016	Huntington's disease	7/596	215/7206	0.00370609866022
ko04670	Leukocyte transendothelial migration	23/596	151/7206	0.00397609812209
ko05134	Legionellosis	14/596	74/7206	0.00423556868063
ko04726	Serotonergic synapse	3/596	137/7206	0.0045325949363
ko04114	Oocyte meiosis	3/596	139/7206	0.00456911078365
ko04514	Cell adhesion molecules (CAMs)	20/596	130/7206	0.00578143077525
ko04713	Circadian entrainment	3/596	136/7206	0.0066171526817
ko04390	Hippo signaling pathway	6/596	188/7206	0.00689427015308
ko04727	GABAergic synapse	2/596	110/7206	0.00800459955503
ko05132	Salmonella infection	16/596	98/7206	0.00819543723916
ko01200	Carbon metabolism	3/596	128/7206	0.00893491468692
ko04540	Gap junction	3/596	128/7206	0.00893491468692
ko04145	Phagosome	23/596	162/7206	0.00900013406801
ko04550	Signaling pathways regulating pluripotency of stem cells	5/596	165/7206	0.00948511250604
ko04664	Fc epsilon RI signaling pathway	13/596	77/7206	0.0110929180772
ko03320	PPAR signaling pathway	12/596	69/7206	0.0127308576584
ko04310	Wnt signaling pathway	6/596	181/7206	0.0128930795081
ko04740	Olfactory transduction	1/596	80/7206	0.0134395517449
ko05143	African trypanosomiasis	7/596	32/7206	0.013861761723
ko05020	Prion diseases	8/596	40/7206	0.0150211016146
ko00980	Metabolism of xenobiotics by cytochrome P450	8/596	40/7206	0.0150211016146
ko05166	HTLV-I infection	36/596	292/7206	0.0163329232971
ko00592	alpha-Linolenic acid metabolism	5/596	19/7206	0.016670074998
ko00140	Steroid hormone biosynthesis	8/596	41/7206	0.0173543355418
ko05012	Parkinson's disease	5/596	155/7206	0.017468257339
ko04920	Adipocytokine signaling pathway	14/596	89/7206	0.0178928495481
ko00051	Fructose and mannose metabolism	8/596	42/7206	0.0199370409359
ko04360	Axon guidance	10/596	233/7206	0.0213225925371
ko05416	Viral myocarditis	10/596	55/7206	0.0220334037131
ko00740	Riboflavin metabolism	3/596	8/7206	0.0229974962139
ko04931	Insulin resistance	19/596	137/7206	0.0264160230188
ko05169	Epstein-Barr virus infection	26/596	206/7206	0.0282457133163
ko04110	Cell cycle	5/596	145/7206	0.0316886808014
ko04972	Pancreatic secretion	3/596	111/7206	0.034535324048
ko00643	Styrene degradation	2/596	4/7206	0.0366149967834
ko04932	Non-alcoholic fatty liver disease (NAFLD)	23/596	182/7206	0.0395437980602
ko04020	Calcium signaling pathway	13/596	265/7206	0.0406446407069
ko05131	Shigellosis	12/596	82/7206	0.0430662166562
ko04137	Mitophagy - animal	12/596	82/7206	0.0430662166562
ko01230	Biosynthesis of amino acids	2/596	85/7206	0.0455314425319
ko04914	Progesterone-mediated oocyte maturation	3/596	104/7206	0.0462979479648
ko04925	Aldosterone synthesis and secretion	3/596	105/7206	0.0468276990764