ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04261	Adrenergic signaling in cardiomyocytes	44/437	205/7206	5.84829804305e-14
ko04260	Cardiac muscle contraction	29/437	98/7206	2.5691339176e-13
ko05410	Hypertrophic cardiomyopathy (HCM)	26/437	100/7206	1.15394471414e-10
ko04080	Neuroactive ligand-receptor interaction	61/437	423/7206	1.27153129115e-10
ko05033	Nicotine addiction	19/437	56/7206	2.66695385587e-10
ko04020	Calcium signaling pathway	44/437	265/7206	5.33994055063e-10
ko04721	Synaptic vesicle cycle	20/437	80/7206	3.49312917124e-08
ko04022	cGMP-PKG signaling pathway	35/437	216/7206	6.51116903534e-08
ko05414	Dilated cardiomyopathy	23/437	112/7206	1.70250310858e-07
ko04921	Oxytocin signaling pathway	33/437	209/7206	2.9354474491e-07
ko04911	Insulin secretion	23/437	117/7206	3.91107389601e-07
ko04713	Circadian entrainment	24/437	136/7206	1.7136932346e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	17/437	79/7206	3.60294686e-06
ko04724	Glutamatergic synapse	25/437	152/7206	3.94927658279e-06
ko04010	MAPK signaling pathway	41/437	321/7206	5.8520183839e-06
ko04922	Glucagon signaling pathway	22/437	128/7206	7.26673287878e-06
ko04970	Salivary secretion	18/437	95/7206	1.24669962228e-05
ko04512	ECM-receptor interaction	16/437	79/7206	1.58114981824e-05
ko04727	GABAergic synapse	19/437	110/7206	2.84423634607e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	15/437	74/7206	2.87946423534e-05
ko04964	Proximal tubule bicarbonate reclamation	9/437	29/7206	3.43820466698e-05
ko04360	Axon guidance	30/437	233/7206	7.09917956696e-05
ko01200	Carbon metabolism	20/437	128/7206	7.78887435531e-05
ko00010	Glycolysis / Gluconeogenesis	14/437	74/7206	0.000117075350891
ko04728	Dopaminergic synapse	25/437	185/7206	0.000129702262759
ko04060	Cytokine-cytokine receptor interaction	1/437	191/7206	0.000153784797497
ko04725	Cholinergic synapse	22/437	160/7206	0.000280083326653
ko05031	Amphetamine addiction	15/437	91/7206	0.000334292123829
ko04974	Protein digestion and absorption	15/437	96/7206	0.000603310304331
ko05164	Influenza A	1/437	167/7206	0.000751113944405
ko04971	Gastric acid secretion	15/437	98/7206	0.00075373286526
ko04723	Retrograde endocannabinoid signaling	22/437	175/7206	0.00103808870916
ko05203	Viral carcinogenesis	5/437	277/7206	0.00113134639795
ko04024	cAMP signaling pathway	31/437	279/7206	0.00116862109926
ko05010	Alzheimer's disease	24/437	202/7206	0.00140335879744
ko04150	mTOR signaling pathway	2/437	184/7206	0.00145158626177
ko05322	Systemic lupus erythematosus	1/437	151/7206	0.00152519449385
ko00250	Alanine, aspartate and glutamate metabolism	8/437	38/7206	0.00167078793268
ko04924	Renin secretion	13/437	86/7206	0.00187429848426
ko03040	Spliceosome	1/437	145/7206	0.00224626818178
ko04514	Cell adhesion molecules (CAMs)	17/437	130/7206	0.00236431059669
ko04720	Long-term potentiation	14/437	99/7206	0.00243127543478
ko04961	Endocrine and other factor-regulated calcium reabsorption	10/437	59/7206	0.0026051346148
ko04120	Ubiquitin mediated proteolysis	1/437	138/7206	0.00326061029913
ko00680	Methane metabolism	7/437	34/7206	0.003699035005
ko04140	Autophagy - animal	2/437	164/7206	0.00425710667731
ko03013	RNA transport	2/437	166/7206	0.00436441506889
ko00020	Citrate cycle (TCA cycle)	7/437	35/7206	0.0043878561089
ko00710	Carbon fixation in photosynthetic organisms	6/437	27/7206	0.00477450335986
ko05416	Viral myocarditis	9/437	55/7206	0.00535953159035
ko04371	Apelin signaling pathway	20/437	177/7206	0.00614836693286
ko01522	Endocrine resistance	1/437	124/7206	0.00686076044359
ko04730	Long-term depression	11/437	78/7206	0.00700921915828
ko04510	Focal adhesion	25/437	240/7206	0.00815247485714
ko04976	Bile secretion	11/437	80/7206	0.00847091054138
ko04142	Lysosome	2/437	151/7206	0.00865518703572
ko04978	Mineral absorption	7/437	40/7206	0.00937047945171
ko05161	Hepatitis B	3/437	173/7206	0.00951183009005
ko04062	Chemokine signaling pathway	4/437	201/7206	0.0100297100798
ko02024	Quorum sensing	4/437	15/7206	0.0106578302073
ko00030	Pentose phosphate pathway	6/437	32/7206	0.0113125376646
ko05166	HTLV-I infection	8/437	292/7206	0.0118012395572
ko01230	Biosynthesis of amino acids	11/437	85/7206	0.0179090812819
ko04626	Plant-pathogen interaction	4/437	18/7206	0.0206876755794
ko04914	Progesterone-mediated oocyte maturation	1/437	104/7206	0.0209218970107
ko04151	PI3K-Akt signaling pathway	35/437	390/7206	0.021179242871
ko01521	EGFR tyrosine kinase inhibitor resistance	1/437	106/7206	0.0213875791017
ko05032	Morphine addiction	13/437	110/7206	0.0232834647419
ko04745	Phototransduction - fly	6/437	38/7206	0.0254014036374
ko04621	NOD-like receptor signaling pathway	3/437	157/7206	0.0259288297362
ko05230	Central carbon metabolism in cancer	10/437	81/7206	0.0299758437551
ko04620	Toll-like receptor signaling pathway	1/437	100/7206	0.031194262866
ko05162	Measles	2/437	120/7206	0.033864431481
ko04668	TNF signaling pathway	2/437	120/7206	0.033864431481
ko04960	Aldosterone-regulated sodium reabsorption	6/437	41/7206	0.035555243148
ko04270	Vascular smooth muscle contraction	16/437	154/7206	0.0376555895452
ko04973	Carbohydrate digestion and absorption	6/437	42/7206	0.0394443921755
ko05030	Cocaine addiction	9/437	73/7206	0.0415974441143
ko04940	Type I diabetes mellitus	5/437	32/7206	0.0416357766108