ko pathway ratio_in_study ratio_in_pop p_value ko04380 Osteoclast differentiation 23/376 134/7206 3.39097506053e-07 ko04650 Natural killer cell mediated cytotoxicity 18/376 97/7206 2.05672081146e-06 ko05164 Influenza A 23/376 167/7206 1.64752508502e-05 ko04060 Cytokine-cytokine receptor interaction 24/376 191/7206 8.15975925612e-05 ko04064 NF-kappa B signaling pathway 15/376 96/7206 0.000118419615961 ko04621 NOD-like receptor signaling pathway 20/376 157/7206 0.000176710875554 ko04610 Complement and coagulation cascades 13/376 79/7206 0.000196872806107 ko04660 T cell receptor signaling pathway 17/376 124/7206 0.000221842227072 ko05167 Kaposi's sarcoma-associated herpesvirus infection 22/376 191/7206 0.000399069210671 ko00120 Primary bile acid biosynthesis 6/376 20/7206 0.000402290372799 ko05150 Staphylococcus aureus infection 8/376 36/7206 0.000425020007591 ko05162 Measles 16/376 120/7206 0.000464990060389 ko05340 Primary immunodeficiency 7/376 30/7206 0.000713116436901 ko04710 Circadian rhythm 8/376 43/7206 0.00147913003941 ko04620 Toll-like receptor signaling pathway 13/376 100/7206 0.00196592058163 ko04217 Necroptosis 19/376 178/7206 0.00295987184055 ko04068 FoxO signaling pathway 18/376 167/7206 0.00383731521094 ko04658 Th1 and Th2 cell differentiation 12/376 96/7206 0.00402083776866 ko04390 Hippo signaling pathway 2/376 188/7206 0.00430757662812 ko04630 Jak-STAT signaling pathway 15/376 132/7206 0.00431168110813 ko00140 Steroid hormone biosynthesis 7/376 41/7206 0.00480344583455 ko05133 Pertussis 11/376 87/7206 0.00529848928647 ko00051 Fructose and mannose metabolism 7/376 42/7206 0.00551211090491 ko04666 Fc gamma R-mediated phagocytosis 14/376 122/7206 0.00570631810157 ko04662 B cell receptor signaling pathway 11/376 88/7206 0.00578074296253 ko04611 Platelet activation 17/376 163/7206 0.00626718032817 ko04664 Fc epsilon RI signaling pathway 10/376 77/7206 0.00637164636615 ko05152 Tuberculosis 19/376 187/7206 0.00653991828776 ko05145 Toxoplasmosis 14/376 126/7206 0.00689076335169 ko03040 Spliceosome 1/376 145/7206 0.00708476706405 ko05034 Alcoholism 4/376 238/7206 0.0073594084875 ko04070 Phosphatidylinositol signaling system 13/376 112/7206 0.00770137140905 ko05321 Inflammatory bowel disease (IBD) 8/376 56/7206 0.00803279701336 ko05160 Hepatitis C 16/376 153/7206 0.00837578041903 ko04723 Retrograde endocannabinoid signaling 2/376 175/7206 0.00880454574164 ko05131 Shigellosis 10/376 82/7206 0.00987227142992 ko04137 Mitophagy - animal 10/376 82/7206 0.00987227142992 ko04668 TNF signaling pathway 13/376 120/7206 0.0109947559984 ko00982 Drug metabolism - cytochrome P450 6/376 37/7206 0.0114024925945 ko03013 RNA transport 2/376 166/7206 0.0123810396842 ko05161 Hepatitis B 17/376 173/7206 0.013497096768 ko04062 Chemokine signaling pathway 19/376 201/7206 0.0142173836079 ko04622 RIG-I-like receptor signaling pathway 8/376 62/7206 0.0145918385956 ko04670 Leukocyte transendothelial migration 15/376 151/7206 0.0146745217814 ko03010 Ribosome 1/376 129/7206 0.0148057826108 ko05140 Leishmaniasis 9/376 75/7206 0.0154998045607 ko04623 Cytosolic DNA-sensing pathway 6/376 41/7206 0.0185266491575 ko04136 Autophagy - other 5/376 31/7206 0.0208541810117 ko04659 Th17 cell differentiation 11/376 106/7206 0.0251291893026 ko00052 Galactose metabolism 5/376 33/7206 0.0267663751087 ko00620 Pyruvate metabolism 6/376 46/7206 0.0310778843468 ko00220 Arginine biosynthesis 4/376 24/7206 0.0338506565921 ko04215 Apoptosis - multiple species 6/376 47/7206 0.0341211600875 ko00362 Benzoate degradation 2/376 6/7206 0.0354163382783 ko05230 Central carbon metabolism in cancer 9/376 81/7206 0.0372418479212 ko05204 Chemical carcinogenesis 6/376 48/7206 0.0373507197935 ko04210 Apoptosis 16/376 180/7206 0.0387864379849 ko04350 TGF-beta signaling pathway 1/376 103/7206 0.0440031627714