ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	206/1305	423/7206	3.76295245255e-50
ko04724	Glutamatergic synapse	94/1305	152/7206	1.15880438552e-33
ko04727	GABAergic synapse	71/1305	110/7206	2.55996497648e-27
ko05032	Morphine addiction	71/1305	110/7206	2.55996497648e-27
ko05033	Nicotine addiction	47/1305	56/7206	9.21574124682e-27
ko04713	Circadian entrainment	76/1305	136/7206	1.99207420802e-23
ko04728	Dopaminergic synapse	87/1305	185/7206	5.97776959205e-20
ko04721	Synaptic vesicle cycle	51/1305	80/7206	1.38343891687e-19
ko04725	Cholinergic synapse	77/1305	160/7206	1.62214294013e-18
ko04723	Retrograde endocannabinoid signaling	81/1305	175/7206	4.03600108197e-18
ko04024	cAMP signaling pathway	109/1305	279/7206	5.64736603579e-17
ko04020	Calcium signaling pathway	104/1305	265/7206	1.68580806111e-16
ko04744	Phototransduction	28/1305	36/7206	8.79348175539e-15
ko04726	Serotonergic synapse	63/1305	137/7206	3.44769766247e-14
ko04742	Taste transduction	37/1305	61/7206	1.4586395165e-13
ko04911	Insulin secretion	55/1305	117/7206	4.89038926663e-13
ko04921	Oxytocin signaling pathway	81/1305	209/7206	9.35661295232e-13
ko03010	Ribosome	1/1305	129/7206	2.09861896757e-10
ko03040	Spliceosome	2/1305	145/7206	2.27116346094e-10
ko04261	Adrenergic signaling in cardiomyocytes	75/1305	205/7206	2.44995890117e-10
ko05031	Amphetamine addiction	42/1305	91/7206	5.91696488775e-10
ko04970	Salivary secretion	43/1305	95/7206	7.92689105614e-10
ko04720	Long-term potentiation	43/1305	99/7206	6.0272992087e-09
ko04022	cGMP-PKG signaling pathway	73/1305	216/7206	2.44133411073e-08
ko04925	Aldosterone synthesis and secretion	42/1305	105/7206	1.19404559776e-07
ko05322	Systemic lupus erythematosus	6/1305	151/7206	2.80736482163e-07
ko03013	RNA transport	8/1305	166/7206	5.98319564059e-07
ko05203	Viral carcinogenesis	21/1305	277/7206	6.07621043868e-07
ko05168	Herpes simplex infection	10/1305	182/7206	7.29497198466e-07
ko05030	Cocaine addiction	31/1305	73/7206	1.47575774528e-06
ko04060	Cytokine-cytokine receptor interaction	12/1305	191/7206	2.32499498578e-06
ko04971	Gastric acid secretion	37/1305	98/7206	3.80469759219e-06
ko04966	Collecting duct acid secretion	15/1305	26/7206	7.10819072559e-06
ko04740	Olfactory transduction	31/1305	80/7206	1.24065940516e-05
ko04110	Cell cycle	8/1305	145/7206	1.54514903417e-05
ko04070	Phosphatidylinositol signaling system	39/1305	112/7206	1.90566123028e-05
ko05164	Influenza A	11/1305	167/7206	2.40346483079e-05
ko03008	Ribosome biogenesis in eukaryotes	2/1305	79/7206	4.49814843326e-05
ko04972	Pancreatic secretion	38/1305	111/7206	4.96474060427e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	28/1305	74/7206	5.22406831712e-05
ko04141	Protein processing in endoplasmic reticulum	14/1305	184/7206	5.98030982148e-05
ko05140	Leishmaniasis	2/1305	75/7206	6.57318040545e-05
ko04072	Phospholipase D signaling pathway	58/1305	197/7206	7.34475252399e-05
ko04514	Cell adhesion molecules (CAMs)	42/1305	130/7206	7.60746918307e-05
ko05161	Hepatitis B	13/1305	173/7206	8.4328521237e-05
ko04745	Phototransduction - fly	17/1305	38/7206	0.000133872341646
ko04923	Regulation of lipolysis in adipocytes	28/1305	77/7206	0.000136070656955
ko04730	Long-term depression	28/1305	78/7206	0.000161842632546
ko05162	Measles	7/1305	120/7206	0.000166337777527
ko04924	Renin secretion	30/1305	86/7206	0.000185814706851
ko04750	Inflammatory mediator regulation of TRP channels	39/1305	122/7206	0.000193684459534
ko05414	Dilated cardiomyopathy	36/1305	112/7206	0.000283819299434
ko04120	Ubiquitin mediated proteolysis	10/1305	138/7206	0.000322351780694
ko00520	Amino sugar and nucleotide sugar metabolism	1/1305	55/7206	0.000328041649244
ko04976	Bile secretion	28/1305	80/7206	0.000336810918781
ko05169	Epstein-Barr virus infection	19/1305	206/7206	0.000444529688284
ko05110	Vibrio cholerae infection	23/1305	63/7206	0.000445779218036
ko04010	MAPK signaling pathway	83/1305	321/7206	0.000461941207459
ko04371	Apelin signaling pathway	51/1305	177/7206	0.000481519228858
ko04915	Estrogen signaling pathway	40/1305	131/7206	0.00050948504585
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	27/1305	79/7206	0.000578632404665
ko04540	Gap junction	39/1305	128/7206	0.000674366542512
ko05205	Proteoglycans in cancer	29/1305	271/7206	0.000922022154364
ko04710	Circadian rhythm	17/1305	43/7206	0.000968182032682
ko04014	Ras signaling pathway	72/1305	279/7206	0.00109960104262
ko04064	NF-kappa B signaling pathway	6/1305	96/7206	0.00119944551132
ko04612	Antigen processing and presentation	4/1305	77/7206	0.00152676649213
ko04621	NOD-like receptor signaling pathway	14/1305	157/7206	0.00156613931157
ko03420	Nucleotide excision repair	1/1305	46/7206	0.00175530366576
ko04360	Axon guidance	61/1305	233/7206	0.00178520749045
ko04626	Plant-pathogen interaction	9/1305	18/7206	0.00205611686414
ko04260	Cardiac muscle contraction	30/1305	98/7206	0.00222155243098
ko04930	Type II diabetes mellitus	19/1305	54/7206	0.00231047114779
ko03022	Basal transcription factors	1/1305	44/7206	0.00266606835136
ko04964	Proximal tubule bicarbonate reclamation	12/1305	29/7206	0.00293104336932
ko05166	HTLV-I infection	34/1305	292/7206	0.00308182990418
ko04961	Endocrine and other factor-regulated calcium reabsorption	20/1305	59/7206	0.00335185601717
ko04510	Focal adhesion	27/1305	240/7206	0.0037114585037
ko04270	Vascular smooth muscle contraction	42/1305	154/7206	0.00417067175921
ko04622	RIG-I-like receptor signaling pathway	3/1305	62/7206	0.00419251165537
ko04658	Th1 and Th2 cell differentiation	7/1305	96/7206	0.00458586611351
ko05133	Pertussis	6/1305	87/7206	0.0046071069765
ko05145	Toxoplasmosis	11/1305	126/7206	0.00474735418121
ko04922	Glucagon signaling pathway	36/1305	128/7206	0.00509819241561
ko04630	Jak-STAT signaling pathway	12/1305	132/7206	0.00579968118311
ko05321	Inflammatory bowel disease (IBD)	3/1305	56/7206	0.0085446046833
ko05131	Shigellosis	6/1305	82/7206	0.00876117822806
ko05144	Malaria	2/1305	45/7206	0.0112744089114
ko04610	Complement and coagulation cascades	6/1305	79/7206	0.0119472061321
ko00240	Pyrimidine metabolism	10/1305	110/7206	0.0120191536702
ko05231	Choline metabolism in cancer	36/1305	134/7206	0.0121716993551
ko00280	Valine, leucine and isoleucine degradation	3/1305	54/7206	0.0122607519571
ko00480	Glutathione metabolism	3/1305	55/7206	0.0125176839913
ko04330	Notch signaling pathway	4/1305	62/7206	0.0125554059964
ko05410	Hypertrophic cardiomyopathy (HCM)	28/1305	100/7206	0.0127933359841
ko04210	Apoptosis	20/1305	180/7206	0.0138304350876
ko03018	RNA degradation	7/1305	84/7206	0.015337083817
ko04933	AGE-RAGE signaling pathway in diabetic complications	14/1305	135/7206	0.017368322853
ko00230	Purine metabolism	48/1305	194/7206	0.018001057022
ko00562	Inositol phosphate metabolism	25/1305	89/7206	0.0181613664823
ko02010	ABC transporters	13/1305	39/7206	0.0202271213018
ko00965	Betalain biosynthesis	3/1305	4/7206	0.0204984555588
ko04115	p53 signaling pathway	6/1305	74/7206	0.0222542029618
ko04213	Longevity regulating pathway - multiple species	24/1305	86/7206	0.0234539077699
ko04912	GnRH signaling pathway	32/1305	122/7206	0.0237943239062
ko04350	TGF-beta signaling pathway	10/1305	103/7206	0.0274838691173
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1305	14/7206	0.0279294216663
ko05206	MicroRNAs in cancer	21/1305	177/7206	0.0292959279759
ko04214	Apoptosis - fly	6/1305	72/7206	0.030277994739
ko04657	IL-17 signaling pathway	8/1305	87/7206	0.0342650600265
ko05416	Viral myocarditis	4/1305	55/7206	0.0342993547106
ko05202	Transcriptional misregulation in cancer	23/1305	188/7206	0.0344416573276
ko00630	Glyoxylate and dicarboxylate metabolism	2/1305	38/7206	0.0348126194262
ko03410	Base excision repair	2/1305	38/7206	0.0348126194262
ko05219	Bladder cancer	3/1305	48/7206	0.0361732587259
ko00980	Metabolism of xenobiotics by cytochrome P450	2/1305	40/7206	0.036302232732
ko05130	Pathogenic Escherichia coli infection	7/1305	77/7206	0.0370681382407
ko04113	Meiosis - yeast	6/1305	70/7206	0.0411086544519
ko04973	Carbohydrate digestion and absorption	13/1305	42/7206	0.0419972928986
ko05418	Fluid shear stress and atherosclerosis	21/1305	173/7206	0.0449230225272