ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	48/814	56/7206	5.78706798389e-38
ko04080	Neuroactive ligand-receptor interaction	143/814	423/7206	1.8367298855e-37
ko04724	Glutamatergic synapse	77/814	152/7206	4.77289669773e-34
ko04727	GABAergic synapse	58/814	110/7206	5.05139735535e-27
ko05032	Morphine addiction	58/814	110/7206	5.05139735535e-27
ko04728	Dopaminergic synapse	72/814	185/7206	4.92015750482e-23
ko04723	Retrograde endocannabinoid signaling	68/814	175/7206	9.37277202294e-22
ko04744	Phototransduction	28/814	36/7206	2.47470521585e-20
ko04713	Circadian entrainment	56/814	136/7206	1.722105996e-19
ko04725	Cholinergic synapse	58/814	160/7206	4.97517495305e-17
ko04742	Taste transduction	32/814	61/7206	2.43771177922e-15
ko04024	cAMP signaling pathway	77/814	279/7206	1.696909022e-14
ko04721	Synaptic vesicle cycle	36/814	80/7206	2.12788877323e-14
ko04726	Serotonergic synapse	46/814	137/7206	2.31397760431e-12
ko04911	Insulin secretion	39/814	117/7206	1.44813199422e-10
ko04740	Olfactory transduction	31/814	80/7206	1.5675743964e-10
ko04921	Oxytocin signaling pathway	56/814	209/7206	2.61121493896e-10
ko05031	Amphetamine addiction	32/814	91/7206	1.44883677308e-09
ko05030	Cocaine addiction	28/814	73/7206	1.60945718915e-09
ko04261	Adrenergic signaling in cardiomyocytes	53/814	205/7206	3.51806544668e-09
ko04020	Calcium signaling pathway	63/814	265/7206	4.36168876583e-09
ko04720	Long-term potentiation	31/814	99/7206	6.00843892048e-08
ko05203	Viral carcinogenesis	7/814	277/7206	6.22151247758e-08
ko04970	Salivary secretion	29/814	95/7206	2.96077627648e-07
ko03040	Spliceosome	1/814	145/7206	8.47364179664e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	24/814	74/7206	9.20894964992e-07
ko05164	Influenza A	3/814	167/7206	5.42367149544e-06
ko04260	Cardiac muscle contraction	27/814	98/7206	6.76499177381e-06
ko04010	MAPK signaling pathway	63/814	321/7206	7.91551930858e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/814	79/7206	1.20289178857e-05
ko04120	Ubiquitin mediated proteolysis	2/814	138/7206	1.68204669453e-05
ko04971	Gastric acid secretion	26/814	98/7206	2.80955330479e-05
ko04972	Pancreatic secretion	28/814	111/7206	2.94710039215e-05
ko04514	Cell adhesion molecules (CAMs)	31/814	130/7206	5.83699067074e-05
ko04060	Cytokine-cytokine receptor interaction	6/814	191/7206	6.41657315164e-05
ko04730	Long-term depression	21/814	78/7206	0.000101578273012
ko03013	RNA transport	5/814	166/7206	0.000159610590564
ko05169	Epstein-Barr virus infection	8/814	206/7206	0.000197452922318
ko05205	Proteoglycans in cancer	13/814	271/7206	0.000257937045944
ko04621	NOD-like receptor signaling pathway	5/814	157/7206	0.000316718378453
ko05168	Herpes simplex infection	7/814	182/7206	0.000504598819404
ko05322	Systemic lupus erythematosus	5/814	151/7206	0.000625965699939
ko04745	Phototransduction - fly	12/814	38/7206	0.000661484578269
ko04022	cGMP-PKG signaling pathway	41/814	216/7206	0.000666537824205
ko05162	Measles	3/814	120/7206	0.000680507453001
ko05414	Dilated cardiomyopathy	25/814	112/7206	0.000734884476337
ko04350	TGF-beta signaling pathway	2/814	103/7206	0.000783243150371
ko04925	Aldosterone synthesis and secretion	24/814	105/7206	0.000840956550624
ko04964	Proximal tubule bicarbonate reclamation	10/814	29/7206	0.000857843421057
ko04110	Cell cycle	5/814	145/7206	0.00125218757204
ko05166	HTLV-I infection	17/814	292/7206	0.00172393362135
ko04610	Complement and coagulation cascades	1/814	79/7206	0.00181436597151
ko03008	Ribosome biogenesis in eukaryotes	1/814	79/7206	0.00181436597151
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/814	182/7206	0.00181825884704
ko04141	Protein processing in endoplasmic reticulum	9/814	184/7206	0.00308598239304
ko05161	Hepatitis B	8/814	173/7206	0.00323751041202
ko05410	Hypertrophic cardiomyopathy (HCM)	21/814	100/7206	0.00395719999778
ko04214	Apoptosis - fly	1/814	72/7206	0.00399003948549
ko03018	RNA degradation	2/814	84/7206	0.00494212817854
ko04140	Autophagy - animal	8/814	164/7206	0.00578008973566
ko04072	Phospholipase D signaling pathway	35/814	197/7206	0.00587224328953
ko04360	Axon guidance	40/814	233/7206	0.00603088809322
ko04915	Estrogen signaling pathway	25/814	131/7206	0.00760834462222
ko00561	Glycerolipid metabolism	1/814	63/7206	0.00826780261334
ko04064	NF-kappa B signaling pathway	3/814	96/7206	0.00830815769485
ko04014	Ras signaling pathway	46/814	279/7206	0.00882828418523
ko04924	Renin secretion	18/814	86/7206	0.00895555121812
ko04150	mTOR signaling pathway	10/814	184/7206	0.00897317187912
ko05034	Alcoholism	40/814	238/7206	0.00897752938023
ko04612	Antigen processing and presentation	2/814	77/7206	0.0102515900696
ko04540	Gap junction	24/814	128/7206	0.0107956007866
ko04976	Bile secretion	17/814	80/7206	0.011190350479
ko04146	Peroxisome	3/814	89/7206	0.0112801586084
ko04750	Inflammatory mediator regulation of TRP channels	23/814	122/7206	0.0131848226564
ko00310	Lysine degradation	2/814	73/7206	0.014637677529
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/814	14/7206	0.0152043833327
ko05140	Leishmaniasis	2/814	75/7206	0.0152083312487
ko05145	Toxoplasmosis	6/814	126/7206	0.0153288058295
ko00564	Glycerophospholipid metabolism	4/814	99/7206	0.0161374109239
ko04930	Type II diabetes mellitus	12/814	54/7206	0.0169529121893
ko00480	Glutathione metabolism	1/814	55/7206	0.0177983639788
ko04142	Lysosome	8/814	151/7206	0.0183577821374
ko05016	Huntington's disease	14/814	215/7206	0.0214484638952
ko05215	Prostate cancer	5/814	111/7206	0.0220090823064
ko04137	Mitophagy - animal	3/814	82/7206	0.0220914098134
ko04068	FoxO signaling pathway	10/814	167/7206	0.0256044240533
ko04630	Jak-STAT signaling pathway	7/814	132/7206	0.0256697015913
ko04668	TNF signaling pathway	6/814	120/7206	0.0278454810545
ko04810	Regulation of actin cytoskeleton	19/814	264/7206	0.0293119630507
ko04218	Cellular senescence	11/814	177/7206	0.0297841344898
ko04974	Protein digestion and absorption	18/814	96/7206	0.0326260409069
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/814	59/7206	0.0369757546131
ko00260	Glycine, serine and threonine metabolism	1/814	48/7206	0.0382245220196
ko04978	Mineral absorption	9/814	40/7206	0.0394339223346
ko05222	Small cell lung cancer	4/814	89/7206	0.0416760888081
ko00330	Arginine and proline metabolism	2/814	61/7206	0.0421238654927
ko04115	p53 signaling pathway	3/814	74/7206	0.0427345826632
ko01524	Platinum drug resistance	3/814	76/7206	0.0430660018014
ko04640	Hematopoietic cell lineage	2/814	64/7206	0.0437826776052
ko04973	Carbohydrate digestion and absorption	9/814	42/7206	0.0480551365232
ko00240	Pyrimidine metabolism	6/814	110/7206	0.048552269605