ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	118/631	423/7206	6.96305518624e-33
ko04724	Glutamatergic synapse	66/631	152/7206	5.54732193826e-31
ko05033	Nicotine addiction	38/631	56/7206	1.06420162179e-27
ko04727	GABAergic synapse	44/631	110/7206	3.10537072301e-19
ko04723	Retrograde endocannabinoid signaling	55/631	175/7206	4.61023087798e-18
ko05032	Morphine addiction	42/631	110/7206	1.5970395549e-17
ko04728	Dopaminergic synapse	54/631	185/7206	3.58213639829e-16
ko04713	Circadian entrainment	45/631	136/7206	6.45489427387e-16
ko04721	Synaptic vesicle cycle	33/631	80/7206	3.45155457024e-15
ko04024	cAMP signaling pathway	65/631	279/7206	5.9065029446e-14
ko04742	Taste transduction	25/631	61/7206	9.74315539352e-12
ko04725	Cholinergic synapse	42/631	160/7206	3.69954347603e-11
ko04911	Insulin secretion	34/631	117/7206	1.46709977351e-10
ko05030	Cocaine addiction	26/631	73/7206	1.57870551831e-10
ko04921	Oxytocin signaling pathway	47/631	209/7206	7.77577619337e-10
ko04261	Adrenergic signaling in cardiomyocytes	46/631	205/7206	1.28058712059e-09
ko05031	Amphetamine addiction	28/631	91/7206	1.50756689866e-09
ko04020	Calcium signaling pathway	53/631	265/7206	5.94025114269e-09
ko05014	Amyotrophic lateral sclerosis (ALS)	24/631	74/7206	7.04452698295e-09
ko04514	Cell adhesion molecules (CAMs)	33/631	130/7206	1.2179171667e-08
ko04726	Serotonergic synapse	34/631	137/7206	1.35745716056e-08
ko04720	Long-term potentiation	27/631	99/7206	5.23967676681e-08
ko04010	MAPK signaling pathway	56/631	321/7206	4.41533579128e-07
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/631	79/7206	2.53492531711e-06
ko04970	Salivary secretion	23/631	95/7206	4.86426919823e-06
ko04060	Cytokine-cytokine receptor interaction	2/631	191/7206	6.52025991904e-06
ko04360	Axon guidance	41/631	233/7206	1.4798066109e-05
ko04972	Pancreatic secretion	24/631	111/7206	2.39283490671e-05
ko04260	Cardiac muscle contraction	22/631	98/7206	2.81376255087e-05
ko03040	Spliceosome	1/631	145/7206	3.95949258519e-05
ko04915	Estrogen signaling pathway	26/631	131/7206	5.8854175886e-05
ko04925	Aldosterone synthesis and secretion	22/631	105/7206	8.57451089671e-05
ko05414	Dilated cardiomyopathy	23/631	112/7206	0.000114704658262
ko04022	cGMP-PKG signaling pathway	36/631	216/7206	0.000128282488664
ko04930	Type II diabetes mellitus	14/631	54/7206	0.000160633858807
ko04072	Phospholipase D signaling pathway	33/631	197/7206	0.000270152294358
ko05203	Viral carcinogenesis	9/631	277/7206	0.000314405549277
ko04730	Long-term depression	17/631	78/7206	0.000328547263603
ko05168	Herpes simplex infection	4/631	182/7206	0.000458670603753
ko04120	Ubiquitin mediated proteolysis	2/631	138/7206	0.000632723782044
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/631	14/7206	0.000716234486687
ko04540	Gap junction	23/631	128/7206	0.000742054800075
ko04621	NOD-like receptor signaling pathway	3/631	157/7206	0.000818134800456
ko05322	Systemic lupus erythematosus	3/631	151/7206	0.00113075411647
ko05205	Proteoglycans in cancer	10/631	271/7206	0.00137272164506
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/631	59/7206	0.00145421612202
ko04971	Gastric acid secretion	18/631	98/7206	0.0031204123973
ko05410	Hypertrophic cardiomyopathy (HCM)	18/631	100/7206	0.00342272713859
ko03013	RNA transport	5/631	166/7206	0.00501665064536
ko05164	Influenza A	5/631	167/7206	0.00506783453382
ko00240	Pyrimidine metabolism	2/631	110/7206	0.00561827184414
ko04966	Collecting duct acid secretion	7/631	26/7206	0.00573122497982
ko04350	TGF-beta signaling pathway	2/631	103/7206	0.00782550076364
ko05162	Measles	3/631	120/7206	0.00877851210872
ko04141	Protein processing in endoplasmic reticulum	7/631	184/7206	0.0117784495505
ko04612	Antigen processing and presentation	1/631	77/7206	0.0133674340103
ko03008	Ribosome biogenesis in eukaryotes	1/631	79/7206	0.0139591817669
ko04962	Vasopressin-regulated water reabsorption	11/631	58/7206	0.0155910486179
ko04630	Jak-STAT signaling pathway	4/631	132/7206	0.0181623985998
ko00515	Mannose type O-glycan biosynthesis	6/631	25/7206	0.0184063743876
ko04214	Apoptosis - fly	1/631	72/7206	0.0194022868521
ko04217	Necroptosis	7/631	178/7206	0.0212514740194
ko04923	Regulation of lipolysis in adipocytes	13/631	77/7206	0.022420776815
ko04146	Peroxisome	2/631	89/7206	0.0225135529764
ko05110	Vibrio cholerae infection	11/631	63/7206	0.0226329156549
ko05010	Alzheimer's disease	27/631	202/7206	0.0229448652148
ko05034	Alcoholism	31/631	238/7206	0.0257454966586
ko04976	Bile secretion	13/631	80/7206	0.0262611868118
ko04973	Carbohydrate digestion and absorption	8/631	42/7206	0.027103157495
ko03018	RNA degradation	2/631	84/7206	0.0318013942903
ko00512	Mucin type O-glycan biosynthesis	6/631	29/7206	0.0366748650569
ko04964	Proximal tubule bicarbonate reclamation	6/631	29/7206	0.0366748650569
ko00330	Arginine and proline metabolism	1/631	61/7206	0.0407740745263
ko00561	Glycerolipid metabolism	1/631	63/7206	0.0411221249617
ko04064	NF-kappa B signaling pathway	3/631	96/7206	0.0453222104102
ko04137	Mitophagy - animal	2/631	82/7206	0.046030835717