ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	136/874	423/7206	1.61828658254e-29
ko04724	Glutamatergic synapse	71/874	152/7206	1.2555465988e-26
ko05033	Nicotine addiction	37/874	56/7206	2.73932356435e-21
ko04713	Circadian entrainment	57/874	136/7206	9.19982313104e-19
ko04728	Dopaminergic synapse	63/874	185/7206	2.55266657029e-15
ko04020	Calcium signaling pathway	77/874	265/7206	6.28108602695e-14
ko04727	GABAergic synapse	44/874	110/7206	7.1220303108e-14
ko05032	Morphine addiction	43/874	110/7206	3.55993737273e-13
ko04723	Retrograde endocannabinoid signaling	57/874	175/7206	4.96179202086e-13
ko04921	Oxytocin signaling pathway	61/874	209/7206	1.67831333237e-11
ko04911	Insulin secretion	42/874	117/7206	1.83583599665e-11
ko04725	Cholinergic synapse	51/874	160/7206	2.17076568022e-11
ko04721	Synaptic vesicle cycle	33/874	80/7206	3.70688093541e-11
ko04720	Long-term potentiation	37/874	99/7206	7.69710406484e-11
ko04024	cAMP signaling pathway	71/874	279/7206	4.47784065561e-10
ko05031	Amphetamine addiction	33/874	91/7206	2.04022678659e-09
ko04726	Serotonergic synapse	41/874	137/7206	1.64934472053e-08
ko04261	Adrenergic signaling in cardiomyocytes	53/874	205/7206	4.66448173775e-08
ko04022	cGMP-PKG signaling pathway	54/874	216/7206	1.13873349421e-07
ko03040	Spliceosome	1/874	145/7206	2.23318154625e-07
ko04970	Salivary secretion	30/874	95/7206	3.87502498491e-07
ko04730	Long-term depression	26/874	78/7206	7.18426469859e-07
ko03010	Ribosome	1/874	129/7206	1.76617510293e-06
ko04745	Phototransduction - fly	16/874	38/7206	3.17416681367e-06
ko04925	Aldosterone synthesis and secretion	30/874	105/7206	5.18843640993e-06
ko04070	Phosphatidylinositol signaling system	31/874	112/7206	6.25556842665e-06
ko04514	Cell adhesion molecules (CAMs)	34/874	130/7206	8.94821031622e-06
ko04010	MAPK signaling pathway	65/874	321/7206	2.24163231671e-05
ko04971	Gastric acid secretion	27/874	98/7206	2.8072220355e-05
ko05168	Herpes simplex infection	6/874	182/7206	4.30813113639e-05
ko05322	Systemic lupus erythematosus	4/874	151/7206	4.33151350711e-05
ko04072	Phospholipase D signaling pathway	44/874	197/7206	5.17739299573e-05
ko03013	RNA transport	5/874	166/7206	5.34994901982e-05
ko05203	Viral carcinogenesis	14/874	277/7206	7.09832795922e-05
ko04710	Circadian rhythm	15/874	43/7206	9.04169574522e-05
ko05030	Cocaine addiction	21/874	73/7206	0.000100167547083
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/874	79/7206	0.000151844426111
ko05014	Amyotrophic lateral sclerosis (ALS)	21/874	74/7206	0.000190571292874
ko04742	Taste transduction	18/874	61/7206	0.000217982857271
ko04360	Axon guidance	47/874	233/7206	0.000327725828477
ko04014	Ras signaling pathway	54/874	279/7206	0.000357937422536
ko04630	Jak-STAT signaling pathway	4/874	132/7206	0.000377850626377
ko04740	Olfactory transduction	21/874	80/7206	0.000436834588209
ko04626	Plant-pathogen interaction	8/874	18/7206	0.000647919345289
ko05164	Influenza A	7/874	167/7206	0.000672927529428
ko04260	Cardiac muscle contraction	24/874	98/7206	0.00080613053343
ko04612	Antigen processing and presentation	1/874	77/7206	0.00116953034321
ko04110	Cell cycle	6/874	145/7206	0.00122508007696
ko04922	Glucagon signaling pathway	28/874	128/7206	0.00151501477491
ko04540	Gap junction	28/874	128/7206	0.00151501477491
ko04750	Inflammatory mediator regulation of TRP channels	27/874	122/7206	0.00177172023617
ko04120	Ubiquitin mediated proteolysis	6/874	138/7206	0.00233173274094
ko04960	Aldosterone-regulated sodium reabsorption	12/874	41/7206	0.0025952217403
ko05161	Hepatitis B	9/874	173/7206	0.00298251589283
ko05169	Epstein-Barr virus infection	12/874	206/7206	0.00327778644769
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/874	14/7206	0.00396537851125
ko00562	Inositol phosphate metabolism	20/874	89/7206	0.00505014404225
ko04964	Proximal tubule bicarbonate reclamation	9/874	29/7206	0.00571938800364
ko04371	Apelin signaling pathway	34/874	177/7206	0.00684061769025
ko05140	Leishmaniasis	2/874	75/7206	0.00688442512433
ko04924	Renin secretion	19/874	86/7206	0.00748531442836
ko05214	Glioma	18/874	79/7206	0.00802578316826
ko04972	Pancreatic secretion	23/874	111/7206	0.00810453857612
ko05010	Alzheimer's disease	37/874	202/7206	0.00858915024388
ko04744	Phototransduction	10/874	36/7206	0.00864427256227
ko04916	Melanogenesis	28/874	142/7206	0.00878972679452
ko04015	Rap1 signaling pathway	48/874	278/7206	0.0110461787411
ko04930	Type II diabetes mellitus	13/874	54/7206	0.011654383082
ko05410	Hypertrophic cardiomyopathy (HCM)	21/874	100/7206	0.0123144550049
ko04711	Circadian rhythm - fly	5/874	13/7206	0.0144686423096
ko05162	Measles	6/874	120/7206	0.0154015396679
ko04141	Protein processing in endoplasmic reticulum	12/874	184/7206	0.0158995133753
ko04270	Vascular smooth muscle contraction	29/874	154/7206	0.0168344815496
ko05414	Dilated cardiomyopathy	22/874	112/7206	0.0190744108591
ko05222	Small cell lung cancer	4/874	89/7206	0.0216358526424
ko05166	HTLV-I infection	23/874	292/7206	0.0218677814557
ko05230	Central carbon metabolism in cancer	17/874	81/7206	0.0239442021037
ko04114	Oocyte meiosis	26/874	139/7206	0.0245691432383
ko04621	NOD-like receptor signaling pathway	10/874	157/7206	0.0252303094936
ko00380	Tryptophan metabolism	1/874	50/7206	0.0264273014344
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/874	59/7206	0.0265826531668
ko04620	Toll-like receptor signaling pathway	5/874	100/7206	0.0291363987185
ko04657	IL-17 signaling pathway	4/874	87/7206	0.0300652690997
ko04966	Collecting duct acid secretion	7/874	26/7206	0.0311947809886
ko04668	TNF signaling pathway	7/874	120/7206	0.0332984943809
ko03022	Basal transcription factors	1/874	44/7206	0.0374056943576
ko05144	Malaria	1/874	45/7206	0.0374490467242
ko00071	Fatty acid degradation	1/874	45/7206	0.0374490467242
ko03420	Nucleotide excision repair	1/874	46/7206	0.0380738812097
ko04064	NF-kappa B signaling pathway	5/874	96/7206	0.0389936748664
ko04210	Apoptosis	13/874	180/7206	0.0481803158601
ko05110	Vibrio cholerae infection	13/874	63/7206	0.0499265918571