ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	58/503	152/7206	4.75396526769e-29
ko05032	Morphine addiction	40/503	110/7206	2.16361155938e-19
ko04723	Retrograde endocannabinoid signaling	50/503	175/7206	9.20529126768e-19
ko04727	GABAergic synapse	39/503	110/7206	1.75233336012e-18
ko05033	Nicotine addiction	27/503	56/7206	3.41138773088e-17
ko04080	Neuroactive ligand-receptor interaction	79/503	423/7206	8.68384298149e-17
ko04713	Circadian entrainment	40/503	136/7206	1.09350806695e-15
ko04728	Dopaminergic synapse	43/503	185/7206	8.25442539066e-13
ko04261	Adrenergic signaling in cardiomyocytes	43/503	205/7206	3.20299734535e-11
ko04020	Calcium signaling pathway	50/503	265/7206	4.50678432272e-11
ko04720	Long-term potentiation	28/503	99/7206	6.85364171386e-11
ko04911	Insulin secretion	30/503	117/7206	2.0617359031e-10
ko04024	cAMP signaling pathway	49/503	279/7206	9.64983281993e-10
ko05031	Amphetamine addiction	24/503	91/7206	7.54862496289e-09
ko05030	Cocaine addiction	21/503	73/7206	1.23589451575e-08
ko04742	Taste transduction	19/503	61/7206	1.45417046224e-08
ko04921	Oxytocin signaling pathway	38/503	209/7206	3.11621256465e-08
ko04725	Cholinergic synapse	32/503	160/7206	3.91310381068e-08
ko04072	Phospholipase D signaling pathway	36/503	197/7206	6.36800226075e-08
ko04726	Serotonergic synapse	28/503	137/7206	1.75102947457e-07
ko04915	Estrogen signaling pathway	27/503	131/7206	2.43478031622e-07
ko04925	Aldosterone synthesis and secretion	23/503	105/7206	6.17690633992e-07
ko04010	MAPK signaling pathway	47/503	321/7206	8.46475642458e-07
ko04970	Salivary secretion	21/503	95/7206	1.63011389301e-06
ko05414	Dilated cardiomyopathy	23/503	112/7206	2.04522915649e-06
ko04070	Phosphatidylinositol signaling system	22/503	112/7206	7.3333162234e-06
ko04060	Cytokine-cytokine receptor interaction	1/503	191/7206	2.02167066037e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	17/503	79/7206	2.33277187865e-05
ko04721	Synaptic vesicle cycle	17/503	80/7206	2.77469700416e-05
ko05168	Herpes simplex infection	1/503	182/7206	4.47608684998e-05
ko04022	cGMP-PKG signaling pathway	32/503	216/7206	5.52332879279e-05
ko04740	Olfactory transduction	16/503	80/7206	0.000103064804571
ko04971	Gastric acid secretion	18/503	98/7206	0.000123796545553
ko04972	Pancreatic secretion	19/503	111/7206	0.000213366857398
ko04923	Regulation of lipolysis in adipocytes	15/503	77/7206	0.000229432943673
ko04730	Long-term depression	15/503	78/7206	0.000266225834199
ko04912	GnRH signaling pathway	20/503	122/7206	0.000403180961124
ko05203	Viral carcinogenesis	6/503	277/7206	0.000426775519702
ko04062	Chemokine signaling pathway	27/503	201/7206	0.0010062170405
ko00562	Inositol phosphate metabolism	15/503	89/7206	0.00114153770722
ko04914	Progesterone-mediated oocyte maturation	17/503	104/7206	0.00129485863789
ko04371	Apelin signaling pathway	24/503	177/7206	0.00146710866285
ko00513	Various types of N-glycan biosynthesis	9/503	42/7206	0.00204381064534
ko04213	Longevity regulating pathway - multiple species	14/503	86/7206	0.00231927984848
ko04918	Thyroid hormone synthesis	14/503	86/7206	0.00231927984848
ko05034	Alcoholism	29/503	238/7206	0.00274181199102
ko04744	Phototransduction	8/503	36/7206	0.00282155811901
ko00512	Mucin type O-glycan biosynthesis	7/503	29/7206	0.00313122026897
ko04211	Longevity regulating pathway	18/503	123/7206	0.00337893437008
ko04260	Cardiac muscle contraction	15/503	98/7206	0.00385112168571
ko04540	Gap junction	18/503	128/7206	0.00417211744372
ko04110	Cell cycle	2/503	145/7206	0.00429944542689
ko05410	Hypertrophic cardiomyopathy (HCM)	15/503	100/7206	0.00441348698034
ko04320	Dorso-ventral axis formation	7/503	31/7206	0.00467242802235
ko04750	Inflammatory mediator regulation of TRP channels	17/503	122/7206	0.0059681169291
ko00515	Mannose type O-glycan biosynthesis	6/503	25/7206	0.00634018320916
ko00510	N-Glycan biosynthesis	9/503	50/7206	0.00698590806504
ko05231	Choline metabolism in cancer	18/503	134/7206	0.00884771496348
ko04114	Oocyte meiosis	18/503	139/7206	0.0103806209191
ko00601	Glycosphingolipid biosynthesis - lacto and neolacto series	6/503	28/7206	0.0112895345021
ko04930	Type II diabetes mellitus	9/503	54/7206	0.0115809575777
ko04916	Melanogenesis	18/503	142/7206	0.0118124189007
ko03013	RNA transport	4/503	166/7206	0.0133584216652
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/503	14/7206	0.0133725320611
ko04270	Vascular smooth muscle contraction	19/503	154/7206	0.0149955519205
ko04014	Ras signaling pathway	30/503	279/7206	0.016072797929
ko05014	Amyotrophic lateral sclerosis (ALS)	11/503	74/7206	0.0175773243625
ko04012	ErbB signaling pathway	14/503	109/7206	0.0221605695032
ko04514	Cell adhesion molecules (CAMs)	16/503	130/7206	0.0228907520779
ko04210	Apoptosis	5/503	180/7206	0.0247166295826
ko04630	Jak-STAT signaling pathway	3/503	132/7206	0.0248654775472
ko03018	RNA degradation	1/503	84/7206	0.0294696912984
ko04015	Rap1 signaling pathway	29/503	278/7206	0.0296462879328
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	5/503	26/7206	0.0314734921301
ko05418	Fluid shear stress and atherosclerosis	5/503	173/7206	0.0328251660405
ko05322	Systemic lupus erythematosus	4/503	151/7206	0.0341323662246
ko00190	Oxidative phosphorylation	3/503	127/7206	0.0342624244141
ko04360	Axon guidance	25/503	233/7206	0.0350153371201
ko05169	Epstein-Barr virus infection	7/503	206/7206	0.0371253093772
ko04144	Endocytosis	34/503	342/7206	0.0378305196224
ko05213	Endometrial cancer	9/503	62/7206	0.0380706496595
ko00910	Nitrogen metabolism	4/503	19/7206	0.039280101168
ko04141	Protein processing in endoplasmic reticulum	6/503	184/7206	0.0402593269305
ko05202	Transcriptional misregulation in cancer	6/503	188/7206	0.0407027192178
ko03008	Ribosome biogenesis in eukaryotes	1/503	79/7206	0.0428402093933
ko04745	Phototransduction - fly	6/503	38/7206	0.0460260623507
ko04350	TGF-beta signaling pathway	2/503	103/7206	0.047904458797