ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	51/596	152/7206	2.78143442266e-19
ko05033	Nicotine addiction	30/596	56/7206	1.43212692291e-18
ko04728	Dopaminergic synapse	54/596	185/7206	2.83098982069e-17
ko04721	Synaptic vesicle cycle	34/596	80/7206	7.4800377084e-17
ko04727	GABAergic synapse	38/596	110/7206	4.05507874325e-15
ko04723	Retrograde endocannabinoid signaling	49/596	175/7206	5.67188364333e-15
ko05032	Morphine addiction	37/596	110/7206	2.48827158135e-14
ko04713	Circadian entrainment	40/596	136/7206	3.37554987511e-13
ko04080	Neuroactive ligand-receptor interaction	73/596	423/7206	7.8387788223e-10
ko04024	cAMP signaling pathway	53/596	279/7206	5.36323887012e-09
ko04360	Axon guidance	46/596	233/7206	1.65154379479e-08
ko04261	Adrenergic signaling in cardiomyocytes	41/596	205/7206	8.09143239625e-08
ko04911	Insulin secretion	28/596	117/7206	1.80756292742e-07
ko04725	Cholinergic synapse	34/596	160/7206	1.97268983201e-07
ko04514	Cell adhesion molecules (CAMs)	29/596	130/7206	5.41982571291e-07
ko04726	Serotonergic synapse	29/596	137/7206	1.71352048127e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	19/596	74/7206	5.74601822043e-06
ko05031	Amphetamine addiction	21/596	91/7206	1.1510134822e-05
ko05030	Cocaine addiction	18/596	73/7206	1.85079214822e-05
ko04060	Cytokine-cytokine receptor interaction	2/596	191/7206	2.28416699686e-05
ko04970	Salivary secretion	21/596	95/7206	2.32258249459e-05
ko05203	Viral carcinogenesis	6/596	277/7206	2.86915454529e-05
ko04720	Long-term potentiation	21/596	99/7206	4.47122033789e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/596	14/7206	5.23953836519e-05
ko04921	Oxytocin signaling pathway	35/596	209/7206	5.39939213228e-05
ko04744	Phototransduction	11/596	36/7206	9.97620380048e-05
ko04010	MAPK signaling pathway	47/596	321/7206	0.000102823450127
ko01200	Carbon metabolism	1/596	128/7206	0.000289897159049
ko05322	Systemic lupus erythematosus	2/596	151/7206	0.000449053730768
ko03040	Spliceosome	2/596	145/7206	0.000636888147285
ko03013	RNA transport	3/596	166/7206	0.000834142226867
ko04966	Collecting duct acid secretion	8/596	26/7206	0.00085288389917
ko04120	Ubiquitin mediated proteolysis	2/596	138/7206	0.000909506956153
ko04730	Long-term depression	15/596	78/7206	0.00156990112967
ko05120	Epithelial cell signaling in Helicobacter pylori infection	17/596	92/7206	0.00158834902654
ko05110	Vibrio cholerae infection	13/596	63/7206	0.00163047409742
ko04022	cGMP-PKG signaling pathway	31/596	216/7206	0.00232933019468
ko04540	Gap junction	21/596	128/7206	0.00291217453476
ko04972	Pancreatic secretion	18/596	111/7206	0.00483264972213
ko04145	Phagosome	24/596	162/7206	0.00539356868419
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/596	15/7206	0.00567416231533
ko04146	Peroxisome	1/596	89/7206	0.00631759603527
ko04964	Proximal tubule bicarbonate reclamation	7/596	29/7206	0.00797686500014
ko04260	Cardiac muscle contraction	16/596	98/7206	0.00819543723916
ko04971	Gastric acid secretion	16/596	98/7206	0.00819543723916
ko05205	Proteoglycans in cancer	11/596	271/7206	0.0091838695903
ko01230	Biosynthesis of amino acids	1/596	85/7206	0.00921642322695
ko04141	Protein processing in endoplasmic reticulum	6/596	184/7206	0.00936110857417
ko04391	Hippo signaling pathway - fly	15/596	90/7206	0.0102405613154
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	13/596	79/7206	0.0131983867964
ko03018	RNA degradation	1/596	84/7206	0.0143354510333
ko04742	Taste transduction	11/596	61/7206	0.0154956979477
ko05146	Amoebiasis	2/596	99/7206	0.0161018486684
ko05162	Measles	3/596	120/7206	0.0177142421999
ko04014	Ras signaling pathway	34/596	279/7206	0.0196054057001
ko04071	Sphingolipid signaling pathway	22/596	162/7206	0.0198130827748
ko04612	Antigen processing and presentation	1/596	77/7206	0.0198749163764
ko05164	Influenza A	6/596	167/7206	0.0223494430037
ko00603	Glycosphingolipid biosynthesis - globo and isoglobo series	3/596	8/7206	0.0229974962139
ko04064	NF-kappa B signaling pathway	2/596	96/7206	0.0231635274319
ko04630	Jak-STAT signaling pathway	4/596	132/7206	0.0242927144276
ko04961	Endocrine and other factor-regulated calcium reabsorption	10/596	59/7206	0.0276079520888
ko05168	Herpes simplex infection	7/596	182/7206	0.0279649457467
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/596	182/7206	0.0279649457467
ko00310	Lysine degradation	1/596	73/7206	0.0293370966169
ko00010	Glycolysis / Gluconeogenesis	1/596	74/7206	0.0300421062738
ko00240	Pyrimidine metabolism	3/596	110/7206	0.0339975006434
ko04015	Rap1 signaling pathway	33/596	278/7206	0.0340067863482
ko04915	Estrogen signaling pathway	18/596	131/7206	0.0350769350802
ko05414	Dilated cardiomyopathy	16/596	112/7206	0.0352215676166
ko04621	NOD-like receptor signaling pathway	6/596	157/7206	0.0393476048623
ko04978	Mineral absorption	7/596	40/7206	0.043408120837
ko04211	Longevity regulating pathway	4/596	123/7206	0.0452562519664
ko04066	HIF-1 signaling pathway	4/596	123/7206	0.0452562519664
ko04350	TGF-beta signaling pathway	3/596	103/7206	0.045958863713
ko05161	Hepatitis B	7/596	173/7206	0.0485599830332