ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	143/908	423/7206	7.23257997142e-32
ko04724	Glutamatergic synapse	75/908	152/7206	6.0051821951e-29
ko05032	Morphine addiction	60/908	110/7206	2.29241953895e-26
ko05033	Nicotine addiction	41/908	56/7206	1.44244928369e-25
ko04727	GABAergic synapse	56/908	110/7206	1.04955801715e-22
ko04728	Dopaminergic synapse	73/908	185/7206	7.19625189902e-21
ko04723	Retrograde endocannabinoid signaling	69/908	175/7206	9.37614923044e-20
ko04721	Synaptic vesicle cycle	43/908	80/7206	7.03212146882e-19
ko04713	Circadian entrainment	58/908	136/7206	1.06025707621e-18
ko04725	Cholinergic synapse	63/908	160/7206	4.33552966631e-18
ko04024	cAMP signaling pathway	86/908	279/7206	2.33510528237e-16
ko04911	Insulin secretion	44/908	117/7206	3.54896067796e-12
ko04726	Serotonergic synapse	47/908	137/7206	2.8853222607e-11
ko04261	Adrenergic signaling in cardiomyocytes	59/908	205/7206	3.23615055398e-10
ko04020	Calcium signaling pathway	70/908	265/7206	5.82840610108e-10
ko04742	Taste transduction	27/908	61/7206	7.99302017512e-10
ko04921	Oxytocin signaling pathway	58/908	209/7206	2.19280551026e-09
ko05031	Amphetamine addiction	33/908	91/7206	5.44805510781e-09
ko04744	Phototransduction	19/908	36/7206	7.05657835071e-09
ko04720	Long-term potentiation	33/908	99/7206	5.93211557158e-08
ko05030	Cocaine addiction	27/908	73/7206	8.37138866557e-08
ko03040	Spliceosome	1/908	145/7206	9.1187545625e-08
ko04360	Axon guidance	58/908	233/7206	1.80617150679e-07
ko04514	Cell adhesion molecules (CAMs)	36/908	130/7206	2.97548849416e-06
ko04925	Aldosterone synthesis and secretion	31/908	105/7206	3.59054136182e-06
ko04022	cGMP-PKG signaling pathway	51/908	216/7206	5.57013020246e-06
ko04010	MAPK signaling pathway	68/908	321/7206	9.58434026488e-06
ko04970	Salivary secretion	28/908	95/7206	1.16900444229e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	23/908	74/7206	2.22150154038e-05
ko03013	RNA transport	5/908	166/7206	2.49417498007e-05
ko05203	Viral carcinogenesis	14/908	277/7206	2.77987864473e-05
ko05322	Systemic lupus erythematosus	4/908	151/7206	2.98518211771e-05
ko04060	Cytokine-cytokine receptor interaction	7/908	191/7206	3.28844847623e-05
ko05168	Herpes simplex infection	7/908	182/7206	6.36356832481e-05
ko04971	Gastric acid secretion	27/908	98/7206	7.57883056068e-05
ko05164	Influenza A	6/908	167/7206	8.1407577075e-05
ko04730	Long-term depression	23/908	78/7206	8.22798164437e-05
ko04072	Phospholipase D signaling pathway	44/908	197/7206	0.000114654013663
ko04972	Pancreatic secretion	29/908	111/7206	0.000119247942227
ko04966	Collecting duct acid secretion	11/908	26/7206	0.000152616981327
ko04915	Estrogen signaling pathway	32/908	131/7206	0.000160196155273
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/908	79/7206	0.000228506815097
ko04120	Ubiquitin mediated proteolysis	5/908	138/7206	0.000409837476164
ko03008	Ribosome biogenesis in eukaryotes	1/908	79/7206	0.000487987318292
ko04014	Ras signaling pathway	55/908	279/7206	0.000605797100204
ko04141	Protein processing in endoplasmic reticulum	9/908	184/7206	0.000650819805842
ko05205	Proteoglycans in cancer	17/908	271/7206	0.000733506928643
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/908	14/7206	0.00075685930445
ko04070	Phosphatidylinositol signaling system	27/908	112/7206	0.000767019607782
ko04924	Renin secretion	22/908	86/7206	0.000867274516009
ko04621	NOD-like receptor signaling pathway	7/908	157/7206	0.000895261262459
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/908	59/7206	0.00103385957396
ko04260	Cardiac muscle contraction	24/908	98/7206	0.00106277453802
ko04740	Olfactory transduction	20/908	80/7206	0.00198639343856
ko04540	Gap junction	28/908	128/7206	0.00284949263172
ko04640	Hematopoietic cell lineage	1/908	64/7206	0.00365753978551
ko04371	Apelin signaling pathway	36/908	177/7206	0.0038086843163
ko05140	Leishmaniasis	2/908	75/7206	0.00465260898281
ko04745	Phototransduction - fly	11/908	38/7206	0.00571108356989
ko05110	Vibrio cholerae infection	16/908	63/7206	0.00612125549022
ko04964	Proximal tubule bicarbonate reclamation	9/908	29/7206	0.00736113855054
ko04064	NF-kappa B signaling pathway	4/908	96/7206	0.00801903392119
ko05414	Dilated cardiomyopathy	24/908	112/7206	0.00890193025237
ko05169	Epstein-Barr virus infection	14/908	206/7206	0.0101002904085
ko00480	Glutathione metabolism	1/908	55/7206	0.0121844577982
ko04612	Antigen processing and presentation	3/908	77/7206	0.0151123197972
ko04217	Necroptosis	12/908	178/7206	0.0157500385713
ko00590	Arachidonic acid metabolism	1/908	52/7206	0.0181602749216
ko00240	Pyrimidine metabolism	6/908	110/7206	0.019811729156
ko05161	Hepatitis B	12/908	173/7206	0.0201325320973
ko04930	Type II diabetes mellitus	13/908	54/7206	0.0205436754414
ko04015	Rap1 signaling pathway	48/908	278/7206	0.0208984420321
ko04923	Regulation of lipolysis in adipocytes	17/908	77/7206	0.022644476421
ko03420	Nucleotide excision repair	1/908	46/7206	0.0250871554163
ko05162	Measles	7/908	120/7206	0.0251826301082
ko05120	Epithelial cell signaling in Helicobacter pylori infection	19/908	92/7206	0.0258859987805
ko00330	Arginine and proline metabolism	2/908	61/7206	0.0300709505217
ko04071	Sphingolipid signaling pathway	30/908	162/7206	0.0301226489058
ko04214	Apoptosis - fly	3/908	72/7206	0.0301682578405
ko01200	Carbon metabolism	8/908	128/7206	0.0303271443494
ko00310	Lysine degradation	3/908	73/7206	0.0309215044202
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/908	15/7206	0.0319004869606
ko05410	Hypertrophic cardiomyopathy (HCM)	20/908	100/7206	0.0324980208266
ko04973	Carbohydrate digestion and absorption	10/908	42/7206	0.0359011802889
ko05034	Alcoholism	41/908	238/7206	0.0363135622173
ko03022	Basal transcription factors	1/908	44/7206	0.0373441091943
ko00071	Fatty acid degradation	1/908	45/7206	0.0384238521152
ko04110	Cell cycle	10/908	145/7206	0.0417995930301
ko04140	Autophagy - animal	12/908	164/7206	0.0420688160421
ko03320	PPAR signaling pathway	3/908	69/7206	0.0423067300248
ko05210	Colorectal cancer	17/908	86/7206	0.0497716499275