ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	140/932	423/7206	7.92983076761e-29
ko04724	Glutamatergic synapse	72/932	152/7206	1.07996290459e-25
ko05033	Nicotine addiction	38/932	56/7206	1.86026068541e-21
ko05032	Morphine addiction	52/932	110/7206	8.61568246491e-19
ko04721	Synaptic vesicle cycle	43/932	80/7206	1.93203558461e-18
ko04728	Dopaminergic synapse	70/932	185/7206	3.22383579975e-18
ko04727	GABAergic synapse	50/932	110/7206	3.25465956356e-17
ko04713	Circadian entrainment	55/932	136/7206	4.9355573262e-16
ko04725	Cholinergic synapse	59/932	160/7206	6.26412361569e-15
ko04723	Retrograde endocannabinoid signaling	60/932	175/7206	1.62075561583e-13
ko04024	cAMP signaling pathway	80/932	279/7206	9.94580653632e-13
ko04911	Insulin secretion	43/932	117/7206	3.67701524213e-11
ko04360	Axon guidance	66/932	233/7206	2.20416959024e-10
ko04261	Adrenergic signaling in cardiomyocytes	60/932	205/7206	4.51454416567e-10
ko04726	Serotonergic synapse	45/932	137/7206	9.35133326845e-10
ko03040	Spliceosome	1/932	145/7206	5.74346767582e-08
ko04020	Calcium signaling pathway	65/932	265/7206	1.77730715039e-07
ko04921	Oxytocin signaling pathway	54/932	209/7206	3.04154441645e-07
ko05030	Cocaine addiction	26/932	73/7206	5.82049906976e-07
ko04742	Taste transduction	23/932	61/7206	8.18281476469e-07
ko04010	MAPK signaling pathway	73/932	321/7206	8.97603189087e-07
ko05203	Viral carcinogenesis	12/932	277/7206	1.52412459634e-06
ko04970	Salivary secretion	30/932	95/7206	1.55258888638e-06
ko05031	Amphetamine addiction	29/932	91/7206	1.87958575125e-06
ko05168	Herpes simplex infection	5/932	182/7206	2.80396546362e-06
ko04514	Cell adhesion molecules (CAMs)	36/932	130/7206	7.42393197614e-06
ko04060	Cytokine-cytokine receptor interaction	7/932	191/7206	1.57256694867e-05
ko03013	RNA transport	5/932	166/7206	1.74121527182e-05
ko05322	Systemic lupus erythematosus	4/932	151/7206	2.05964449719e-05
ko04022	cGMP-PKG signaling pathway	50/932	216/7206	2.97520557146e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	23/932	74/7206	3.39606269439e-05
ko04720	Long-term potentiation	28/932	99/7206	5.08830498479e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/932	79/7206	5.16957789747e-05
ko04744	Phototransduction	14/932	36/7206	7.97502016678e-05
ko04120	Ubiquitin mediated proteolysis	4/932	138/7206	8.83657598541e-05
ko04961	Endocrine and other factor-regulated calcium reabsorption	19/932	59/7206	9.47843450601e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/932	14/7206	0.000111047965044
ko04141	Protein processing in endoplasmic reticulum	8/932	184/7206	0.000128466764176
ko04972	Pancreatic secretion	29/932	111/7206	0.000152544010569
ko05205	Proteoglycans in cancer	16/932	271/7206	0.000197701518142
ko04730	Long-term depression	22/932	78/7206	0.000265376769871
ko04070	Phosphatidylinositol signaling system	28/932	112/7206	0.000508968286811
ko03008	Ribosome biogenesis in eukaryotes	1/932	79/7206	0.000514499849893
ko05164	Influenza A	8/932	167/7206	0.000638213926052
ko04621	NOD-like receptor signaling pathway	7/932	157/7206	0.000646680516299
ko04260	Cardiac muscle contraction	25/932	98/7206	0.000667649821848
ko04971	Gastric acid secretion	25/932	98/7206	0.000667649821848
ko04966	Collecting duct acid secretion	10/932	26/7206	0.00093536786893
ko00240	Pyrimidine metabolism	4/932	110/7206	0.00144645910648
ko04064	NF-kappa B signaling pathway	3/932	96/7206	0.00184796981113
ko04925	Aldosterone synthesis and secretion	25/932	105/7206	0.00187816655165
ko04014	Ras signaling pathway	54/932	279/7206	0.00189139442144
ko04217	Necroptosis	10/932	178/7206	0.00206309105159
ko04640	Hematopoietic cell lineage	1/932	64/7206	0.00235272604536
ko04391	Hippo signaling pathway - fly	22/932	90/7206	0.00239144660746
ko04964	Proximal tubule bicarbonate reclamation	10/932	29/7206	0.00245160966729
ko05414	Dilated cardiomyopathy	26/932	112/7206	0.00251829651686
ko01200	Carbon metabolism	6/932	128/7206	0.00311564702772
ko04924	Renin secretion	21/932	86/7206	0.00316305909835
ko04072	Phospholipase D signaling pathway	40/932	197/7206	0.00339665732001
ko04915	Estrogen signaling pathway	29/932	131/7206	0.00342781597836
ko04146	Peroxisome	3/932	89/7206	0.00373268723669
ko05140	Leishmaniasis	2/932	75/7206	0.00475536234684
ko05169	Epstein-Barr virus infection	14/932	206/7206	0.00592498943861
ko04214	Apoptosis - fly	2/932	72/7206	0.00692849710047
ko00280	Valine, leucine and isoleucine degradation	1/932	54/7206	0.00771498398939
ko00480	Glutathione metabolism	1/932	55/7206	0.00772305651559
ko03018	RNA degradation	3/932	84/7206	0.00780504711163
ko04540	Gap junction	27/932	128/7206	0.0107281024107
ko00590	Arachidonic acid metabolism	1/932	52/7206	0.0114561302364
ko04930	Type II diabetes mellitus	14/932	54/7206	0.012276609265
ko04144	Endocytosis	60/932	342/7206	0.0129498031269
ko00561	Glycerolipid metabolism	2/932	63/7206	0.0137878862727
ko04612	Antigen processing and presentation	3/932	77/7206	0.0153164765238
ko04630	Jak-STAT signaling pathway	8/932	132/7206	0.0174769250141
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/932	182/7206	0.0181355679967
ko04973	Carbohydrate digestion and absorption	11/932	42/7206	0.0182049255941
ko05162	Measles	7/932	120/7206	0.0186666883342
ko05110	Vibrio cholerae infection	15/932	63/7206	0.0211338459256
ko00310	Lysine degradation	3/932	73/7206	0.0211907702116
ko05410	Hypertrophic cardiomyopathy (HCM)	21/932	100/7206	0.0230632105893
ko00562	Inositol phosphate metabolism	19/932	89/7206	0.0247504540588
ko05144	Malaria	1/932	45/7206	0.024829823573
ko03420	Nucleotide excision repair	1/932	46/7206	0.0251167546225
ko04390	Hippo signaling pathway	35/932	188/7206	0.0267853540713
ko05161	Hepatitis B	13/932	173/7206	0.0291364389992
ko04137	Mitophagy - animal	4/932	82/7206	0.0295905659006
ko04140	Autophagy - animal	12/932	164/7206	0.0331008976097
ko05210	Colorectal cancer	18/932	86/7206	0.0343371224342
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/932	15/7206	0.0352837798594
ko04960	Aldosterone-regulated sodium reabsorption	10/932	41/7206	0.0359653212857
ko03022	Basal transcription factors	1/932	44/7206	0.038304261065
ko04976	Bile secretion	17/932	80/7206	0.0418468852492
ko05321	Inflammatory bowel disease (IBD)	2/932	56/7206	0.0421070074508
ko04071	Sphingolipid signaling pathway	30/932	162/7206	0.0429561201989
ko00512	Mucin type O-glycan biosynthesis	8/932	29/7206	0.0447967687539
ko04658	Th1 and Th2 cell differentiation	6/932	96/7206	0.0467183404958