ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	47/881	152/7206	5.65370944643e-10
ko04080	Neuroactive ligand-receptor interaction	95/881	423/7206	1.36187560878e-09
ko04713	Circadian entrainment	42/881	136/7206	4.94749909626e-09
ko04020	Calcium signaling pathway	63/881	265/7206	9.49614987495e-08
ko04921	Oxytocin signaling pathway	53/881	209/7206	1.33832810953e-07
ko04022	cGMP-PKG signaling pathway	53/881	216/7206	4.09886825641e-07
ko04727	GABAergic synapse	33/881	110/7206	4.71849223432e-07
ko05033	Nicotine addiction	21/881	56/7206	1.07663374092e-06
ko04744	Phototransduction	16/881	36/7206	1.4721559535e-06
ko03010	Ribosome	1/881	129/7206	1.8267434406e-06
ko03040	Spliceosome	2/881	145/7206	2.17890760587e-06
ko04911	Insulin secretion	33/881	117/7206	2.41206865695e-06
ko04070	Phosphatidylinositol signaling system	32/881	112/7206	2.71183328304e-06
ko05032	Morphine addiction	31/881	110/7206	5.07451147347e-06
ko04970	Salivary secretion	28/881	95/7206	5.09530500699e-06
ko04720	Long-term potentiation	29/881	99/7206	6.2197447979e-06
ko05031	Amphetamine addiction	27/881	91/7206	6.52951455554e-06
ko04971	Gastric acid secretion	28/881	98/7206	1.24108416893e-05
ko04925	Aldosterone synthesis and secretion	29/881	105/7206	1.51358168554e-05
ko04024	cAMP signaling pathway	59/881	279/7206	1.53946487863e-05
ko04745	Phototransduction - fly	15/881	38/7206	1.82931491239e-05
ko04710	Circadian rhythm	16/881	43/7206	2.32186294308e-05
ko04922	Glucagon signaling pathway	33/881	128/7206	2.68544417739e-05
ko04725	Cholinergic synapse	38/881	160/7206	4.13388294624e-05
ko05322	Systemic lupus erythematosus	4/881	151/7206	4.31926314587e-05
ko04726	Serotonergic synapse	34/881	137/7206	5.26067152479e-05
ko04728	Dopaminergic synapse	42/881	185/7206	5.34735741386e-05
ko05203	Viral carcinogenesis	14/881	277/7206	7.2254966804e-05
ko04110	Cell cycle	4/881	145/7206	9.06839104622e-05
ko03013	RNA transport	6/881	166/7206	0.000166388241585
ko04261	Adrenergic signaling in cardiomyocytes	43/881	205/7206	0.000310554011175
ko04730	Long-term depression	21/881	78/7206	0.000347767201006
ko04371	Apelin signaling pathway	38/881	177/7206	0.000424415675291
ko04721	Synaptic vesicle cycle	21/881	80/7206	0.000480980190961
ko04966	Collecting duct acid secretion	10/881	26/7206	0.000595483497922
ko03008	Ribosome biogenesis in eukaryotes	1/881	79/7206	0.00076053946969
ko05224	Breast cancer	9/881	174/7206	0.00220528211616
ko04514	Cell adhesion molecules (CAMs)	28/881	130/7206	0.00258672683973
ko05169	Epstein-Barr virus infection	12/881	206/7206	0.00331764145839
ko05200	Pathways in cancer	40/881	492/7206	0.00337835195699
ko04626	Plant-pathogen interaction	7/881	18/7206	0.00374498845994
ko04270	Vascular smooth muscle contraction	31/881	154/7206	0.00409568617942
ko05130	Pathogenic Escherichia coli infection	2/881	77/7206	0.00473196750192
ko04723	Retrograde endocannabinoid signaling	34/881	175/7206	0.00494944253551
ko04740	Olfactory transduction	19/881	80/7206	0.00504624419462
ko04137	Mitophagy - animal	19/881	82/7206	0.00565457280603
ko04350	TGF-beta signaling pathway	4/881	103/7206	0.00586134927649
ko04964	Proximal tubule bicarbonate reclamation	9/881	29/7206	0.00603109655477
ko00120	Primary bile acid biosynthesis	7/881	20/7206	0.00732677422415
ko04072	Phospholipase D signaling pathway	37/881	197/7206	0.00767417429198
ko04750	Inflammatory mediator regulation of TRP channels	25/881	122/7206	0.00776943840843
ko05168	Herpes simplex infection	11/881	182/7206	0.00799324124453
ko04136	Autophagy - other	9/881	31/7206	0.00970332161283
ko04550	Signaling pathways regulating pluripotency of stem cells	10/881	165/7206	0.0113118679289
ko04924	Renin secretion	19/881	86/7206	0.0115600165194
ko03050	Proteasome	1/881	54/7206	0.0117086981981
ko00520	Amino sugar and nucleotide sugar metabolism	1/881	55/7206	0.0117714843241
ko04960	Aldosterone-regulated sodium reabsorption	11/881	41/7206	0.013130023197
ko05217	Basal cell carcinoma	2/881	68/7206	0.0142568580158
ko04014	Ras signaling pathway	48/881	279/7206	0.0149265694042
ko04141	Protein processing in endoplasmic reticulum	12/881	184/7206	0.0160151798701
ko04742	Taste transduction	14/881	61/7206	0.0168378592722
ko00010	Glycolysis / Gluconeogenesis	16/881	74/7206	0.0193403320199
ko00592	alpha-Linolenic acid metabolism	6/881	19/7206	0.0218511773183
ko00620	Pyruvate metabolism	11/881	46/7206	0.0226483941327
ko05219	Bladder cancer	1/881	48/7206	0.0254385915356
ko05016	Huntington's disease	16/881	215/7206	0.0264788134176
ko00240	Pyrimidine metabolism	6/881	110/7206	0.0268954152927
ko00362	Benzoate degradation	3/881	6/7206	0.0273864544989
ko00680	Methane metabolism	9/881	34/7206	0.0298087877989
ko04214	Apoptosis - fly	3/881	72/7206	0.0299994938562
ko04657	IL-17 signaling pathway	4/881	87/7206	0.0303514713153
ko00051	Fructose and mannose metabolism	10/881	42/7206	0.0310643889729
ko00562	Inositol phosphate metabolism	18/881	89/7206	0.0321460957976
ko04930	Type II diabetes mellitus	12/881	54/7206	0.0345646524538
ko04120	Ubiquitin mediated proteolysis	9/881	138/7206	0.0357401523031
ko03420	Nucleotide excision repair	1/881	46/7206	0.0383482176694
ko04260	Cardiac muscle contraction	19/881	98/7206	0.0415354351529
ko04113	Meiosis - yeast	3/881	70/7206	0.0419499499016
ko00564	Glycerophospholipid metabolism	19/881	99/7206	0.0430368917154
ko01230	Biosynthesis of amino acids	17/881	85/7206	0.0430786921269
ko05014	Amyotrophic lateral sclerosis (ALS)	15/881	74/7206	0.0470701238011