ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	184/1078	423/7206	1.18176434139e-48
ko04724	Glutamatergic synapse	85/1078	152/7206	2.40065305479e-32
ko05033	Nicotine addiction	48/1078	56/7206	4.24291613358e-32
ko04727	GABAergic synapse	66/1078	110/7206	8.96729768199e-28
ko05032	Morphine addiction	63/1078	110/7206	5.5457011548e-25
ko04713	Circadian entrainment	67/1078	136/7206	1.55737662763e-21
ko04721	Synaptic vesicle cycle	48/1078	80/7206	1.69868949549e-20
ko04723	Retrograde endocannabinoid signaling	75/1078	175/7206	2.00594642097e-19
ko04728	Dopaminergic synapse	77/1078	185/7206	5.34004920058e-19
ko04744	Phototransduction	29/1078	36/7206	2.45956254794e-18
ko04725	Cholinergic synapse	69/1078	160/7206	3.93714014419e-18
ko04742	Taste transduction	38/1078	61/7206	2.84894445824e-17
ko04911	Insulin secretion	54/1078	117/7206	5.35811033701e-16
ko04024	cAMP signaling pathway	92/1078	279/7206	1.31561845717e-14
ko04726	Serotonergic synapse	54/1078	137/7206	1.61653528234e-12
ko04740	Olfactory transduction	38/1078	80/7206	4.07928708387e-12
ko04020	Calcium signaling pathway	80/1078	265/7206	1.1386279658e-10
ko04921	Oxytocin signaling pathway	67/1078	209/7206	3.16387500937e-10
ko05031	Amphetamine addiction	37/1078	91/7206	1.97183757218e-09
ko04261	Adrenergic signaling in cardiomyocytes	64/1078	205/7206	2.00974338251e-09
ko03040	Spliceosome	1/1078	145/7206	2.18261674121e-09
ko05203	Viral carcinogenesis	11/1078	277/7206	2.93226348571e-09
ko04720	Long-term potentiation	38/1078	99/7206	8.13663251144e-09
ko04970	Salivary secretion	36/1078	95/7206	2.98553657194e-08
ko04971	Gastric acid secretion	35/1078	98/7206	3.70057671931e-07
ko05168	Herpes simplex infection	6/1078	182/7206	4.32871700437e-07
ko05030	Cocaine addiction	28/1078	73/7206	7.70378915793e-07
ko03013	RNA transport	6/1078	166/7206	2.66474914532e-06
ko05164	Influenza A	6/1078	167/7206	2.6711127705e-06
ko04966	Collecting duct acid secretion	14/1078	26/7206	4.27558606377e-06
ko04120	Ubiquitin mediated proteolysis	4/1078	138/7206	5.19434716958e-06
ko04925	Aldosterone synthesis and secretion	34/1078	105/7206	5.63007094788e-06
ko04060	Cytokine-cytokine receptor interaction	9/1078	191/7206	7.84919710868e-06
ko04976	Bile secretion	28/1078	80/7206	8.51343680142e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	26/1078	74/7206	1.82854821215e-05
ko04972	Pancreatic secretion	34/1078	111/7206	2.18013412211e-05
ko04964	Proximal tubule bicarbonate reclamation	14/1078	29/7206	2.20787111417e-05
ko05322	Systemic lupus erythematosus	6/1078	151/7206	2.38543651691e-05
ko05205	Proteoglycans in cancer	18/1078	271/7206	2.66460848743e-05
ko04621	NOD-like receptor signaling pathway	7/1078	157/7206	3.70494858516e-05
ko04022	cGMP-PKG signaling pathway	55/1078	216/7206	4.01526845756e-05
ko04745	Phototransduction - fly	16/1078	38/7206	4.81447868918e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	26/1078	79/7206	4.87273782413e-05
ko05162	Measles	4/1078	120/7206	4.91382551559e-05
ko04141	Protein processing in endoplasmic reticulum	10/1078	184/7206	6.02717871752e-05
ko05169	Epstein-Barr virus infection	12/1078	206/7206	6.09953421287e-05
ko04260	Cardiac muscle contraction	30/1078	98/7206	7.77713784311e-05
ko04110	Cell cycle	7/1078	145/7206	0.000146122625734
ko04730	Long-term depression	25/1078	78/7206	0.000149647611064
ko04010	MAPK signaling pathway	73/1078	321/7206	0.000153516618058
ko04514	Cell adhesion molecules (CAMs)	36/1078	130/7206	0.00015574897317
ko04072	Phospholipase D signaling pathway	49/1078	197/7206	0.000229585010441
ko04360	Axon guidance	56/1078	233/7206	0.00023838923331
ko04540	Gap junction	35/1078	128/7206	0.000240163272338
ko04961	Endocrine and other factor-regulated calcium reabsorption	20/1078	59/7206	0.000284782397255
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/1078	182/7206	0.000296404957373
ko04924	Renin secretion	26/1078	86/7206	0.000331631136255
ko05166	HTLV-I infection	24/1078	292/7206	0.000561274634009
ko03008	Ribosome biogenesis in eukaryotes	2/1078	79/7206	0.000644826154643
ko05140	Leishmaniasis	2/1078	75/7206	0.000907808893852
ko04064	NF-kappa B signaling pathway	4/1078	96/7206	0.00129910472542
ko04214	Apoptosis - fly	2/1078	72/7206	0.00132950942495
ko05161	Hepatitis B	12/1078	173/7206	0.00163586893966
ko04140	Autophagy - animal	11/1078	164/7206	0.00175991852569
ko05110	Vibrio cholerae infection	19/1078	63/7206	0.0019980600503
ko04974	Protein digestion and absorption	26/1078	96/7206	0.00210515881044
ko00520	Amino sugar and nucleotide sugar metabolism	1/1078	55/7206	0.00211528065359
ko00480	Glutathione metabolism	1/1078	55/7206	0.00211528065359
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/1078	14/7206	0.00214807778917
ko04610	Complement and coagulation cascades	3/1078	79/7206	0.0023384422049
ko04146	Peroxisome	4/1078	89/7206	0.00259752404881
ko00240	Pyrimidine metabolism	6/1078	110/7206	0.00278979073316
ko04750	Inflammatory mediator regulation of TRP channels	31/1078	122/7206	0.00288029977276
ko04612	Antigen processing and presentation	3/1078	77/7206	0.00337417428844
ko04657	IL-17 signaling pathway	4/1078	87/7206	0.00367566177352
ko04640	Hematopoietic cell lineage	2/1078	64/7206	0.00419214236262
ko05016	Huntington's disease	18/1078	215/7206	0.00468457010735
ko05414	Dilated cardiomyopathy	28/1078	112/7206	0.00470169245463
ko04070	Phosphatidylinositol signaling system	28/1078	112/7206	0.00470169245463
ko03018	RNA degradation	4/1078	84/7206	0.00517536378889
ko00330	Arginine and proline metabolism	2/1078	61/7206	0.00608704067788
ko00260	Glycine, serine and threonine metabolism	1/1078	48/7206	0.00712314168794
ko04350	TGF-beta signaling pathway	6/1078	103/7206	0.0074819266501
ko04014	Ras signaling pathway	58/1078	279/7206	0.00773130144201
ko05418	Fluid shear stress and atherosclerosis	14/1078	173/7206	0.00920410506984
ko03022	Basal transcription factors	1/1078	44/7206	0.0105463945399
ko05144	Malaria	1/1078	45/7206	0.0105681173418
ko00071	Fatty acid degradation	1/1078	45/7206	0.0105681173418
ko04217	Necroptosis	15/1078	178/7206	0.0105733358367
ko03420	Nucleotide excision repair	1/1078	46/7206	0.0108951518715
ko05321	Inflammatory bowel disease (IBD)	2/1078	56/7206	0.0129832815951
ko04978	Mineral absorption	12/1078	40/7206	0.013011346731
ko04915	Estrogen signaling pathway	30/1078	131/7206	0.0132633090992
ko04658	Th1 and Th2 cell differentiation	6/1078	96/7206	0.0135695040457
ko01524	Platinum drug resistance	4/1078	76/7206	0.0142970087197
ko00280	Valine, leucine and isoleucine degradation	2/1078	54/7206	0.0192831221033
ko04668	TNF signaling pathway	9/1078	120/7206	0.0194654924151
ko04210	Apoptosis	16/1078	180/7206	0.0194968317743
ko04622	RIG-I-like receptor signaling pathway	3/1078	62/7206	0.0196149824244
ko00561	Glycerolipid metabolism	3/1078	63/7206	0.0197531085785
ko05215	Prostate cancer	8/1078	111/7206	0.0215509491504
ko00564	Glycerophospholipid metabolism	7/1078	99/7206	0.0229706661616
ko05145	Toxoplasmosis	10/1078	126/7206	0.0230257584645
ko04620	Toll-like receptor signaling pathway	7/1078	100/7206	0.0230543388605
ko00980	Metabolism of xenobiotics by cytochrome P450	1/1078	40/7206	0.0236481249076
ko04218	Cellular senescence	16/1078	177/7206	0.0245986132907
ko00140	Steroid hormone biosynthesis	1/1078	41/7206	0.0246566371084
ko04973	Carbohydrate digestion and absorption	12/1078	42/7206	0.0262970992024
ko04138	Autophagy - yeast	5/1078	81/7206	0.0267248108451
ko01212	Fatty acid metabolism	3/1078	60/7206	0.0277595430225
ko04930	Type II diabetes mellitus	14/1078	54/7206	0.0330689422492
ko05133	Pertussis	6/1078	87/7206	0.0332783449112
ko00982	Drug metabolism - cytochrome P450	1/1078	37/7206	0.0348397552322
ko04630	Jak-STAT signaling pathway	11/1078	132/7206	0.0351682056316
ko04341	Hedgehog signaling pathway - fly	1/1078	38/7206	0.0360726095629
ko00620	Pyruvate metabolism	2/1078	46/7206	0.0381937767416
ko05217	Basal cell carcinoma	4/1078	68/7206	0.0383145038331
ko00270	Cysteine and methionine metabolism	2/1078	47/7206	0.0383580968
ko05219	Bladder cancer	2/1078	48/7206	0.0392496897175
ko05012	Parkinson's disease	14/1078	155/7206	0.0395904762428
ko04626	Plant-pathogen interaction	6/1078	18/7206	0.0412104177712
ko01200	Carbon metabolism	11/1078	128/7206	0.0445210016424
ko05220	Chronic myeloid leukemia	6/1078	85/7206	0.0450155973774
ko04918	Thyroid hormone synthesis	20/1078	86/7206	0.0460041679904
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	8/1078	26/7206	0.0460434786358
ko00310	Lysine degradation	5/1078	73/7206	0.0481984268789
ko04115	p53 signaling pathway	5/1078	74/7206	0.0482680816315
ko04142	Lysosome	14/1078	151/7206	0.0494623376058