ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	35/792	56/7206	1.9147507011e-20
ko04080	Neuroactive ligand-receptor interaction	111/792	423/7206	9.38585194405e-20
ko04360	Axon guidance	69/792	233/7206	2.08571648091e-15
ko04724	Glutamatergic synapse	53/792	152/7206	2.41473701668e-15
ko04728	Dopaminergic synapse	56/792	185/7206	3.80682837613e-13
ko04721	Synaptic vesicle cycle	32/792	80/7206	1.4037999593e-11
ko04713	Circadian entrainment	41/792	136/7206	6.80505506801e-10
ko04727	GABAergic synapse	35/792	110/7206	2.52066446292e-09
ko05032	Morphine addiction	35/792	110/7206	2.52066446292e-09
ko04514	Cell adhesion molecules (CAMs)	38/792	130/7206	7.5438121143e-09
ko04024	cAMP signaling pathway	61/792	279/7206	7.96273200866e-08
ko05030	Cocaine addiction	25/792	73/7206	9.72328424942e-08
ko04723	Retrograde endocannabinoid signaling	44/792	175/7206	1.00545920278e-07
ko04725	Cholinergic synapse	41/792	160/7206	1.26714608831e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	25/792	74/7206	1.31816067967e-07
ko04911	Insulin secretion	32/792	117/7206	6.21968835828e-07
ko05031	Amphetamine addiction	27/792	91/7206	8.22904134567e-07
ko03040	Spliceosome	1/792	145/7206	1.30956474514e-06
ko05203	Viral carcinogenesis	10/792	277/7206	8.53317907933e-06
ko01200	Carbon metabolism	1/792	128/7206	1.02294587657e-05
ko03013	RNA transport	3/792	166/7206	1.24225034383e-05
ko04010	MAPK signaling pathway	61/792	321/7206	1.4317662582e-05
ko04120	Ubiquitin mediated proteolysis	2/792	138/7206	2.54409811231e-05
ko04060	Cytokine-cytokine receptor interaction	5/792	191/7206	2.91725004091e-05
ko05168	Herpes simplex infection	5/792	182/7206	5.73253549619e-05
ko04742	Taste transduction	18/792	61/7206	6.06080716627e-05
ko04726	Serotonergic synapse	31/792	137/7206	7.70032393789e-05
ko04950	Maturity onset diabetes of the young	11/792	29/7206	0.000141031268504
ko04261	Adrenergic signaling in cardiomyocytes	41/792	205/7206	0.000148096007841
ko04141	Protein processing in endoplasmic reticulum	6/792	184/7206	0.000180164426233
ko05224	Breast cancer	35/792	174/7206	0.000320639348731
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/792	14/7206	0.000322983220519
ko04550	Signaling pathways regulating pluripotency of stem cells	33/792	165/7206	0.000569965186037
ko04146	Peroxisome	1/792	89/7206	0.000860435463596
ko04720	Long-term potentiation	22/792	99/7206	0.00101396430961
ko05217	Basal cell carcinoma	17/792	68/7206	0.00118929772704
ko03018	RNA degradation	1/792	84/7206	0.00121146251767
ko01230	Biosynthesis of amino acids	1/792	85/7206	0.00125461998889
ko03008	Ribosome biogenesis in eukaryotes	1/792	79/7206	0.00175646539283
ko04621	NOD-like receptor signaling pathway	6/792	157/7206	0.00178959599212
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/792	182/7206	0.00244310432093
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/792	79/7206	0.00293517328642
ko00240	Pyrimidine metabolism	3/792	110/7206	0.00297468647271
ko05322	Systemic lupus erythematosus	6/792	151/7206	0.00342993792981
ko00010	Glycolysis / Gluconeogenesis	1/792	74/7206	0.0040494999558
ko04970	Salivary secretion	20/792	95/7206	0.00418069389737
ko04391	Hippo signaling pathway - fly	19/792	90/7206	0.00558830451105
ko04921	Oxytocin signaling pathway	36/792	209/7206	0.00662006899107
ko05164	Influenza A	8/792	167/7206	0.00797364194269
ko04064	NF-kappa B signaling pathway	3/792	96/7206	0.00809446139957
ko00564	Glycerophospholipid metabolism	3/792	99/7206	0.00849020763131
ko04540	Gap junction	24/792	128/7206	0.00933884242878
ko04962	Vasopressin-regulated water reabsorption	13/792	58/7206	0.0100594887124
ko04964	Proximal tubule bicarbonate reclamation	8/792	29/7206	0.0107635215556
ko04015	Rap1 signaling pathway	44/792	278/7206	0.0109285369541
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/792	59/7206	0.0113392329063
ko05162	Measles	5/792	120/7206	0.0118067632105
ko04972	Pancreatic secretion	21/792	111/7206	0.01314359528
ko04730	Long-term depression	16/792	78/7206	0.015856762419
ko04512	ECM-receptor interaction	16/792	79/7206	0.0165510589539
ko04966	Collecting duct acid secretion	7/792	26/7206	0.0191077028745
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	7/792	26/7206	0.0191077028745
ko04611	Platelet activation	9/792	163/7206	0.0219313538835
ko04140	Autophagy - animal	9/792	164/7206	0.0221001129017
ko05146	Amoebiasis	4/792	99/7206	0.0224687152509
ko00230	Purine metabolism	12/792	194/7206	0.0268912278575
ko04022	cGMP-PKG signaling pathway	34/792	216/7206	0.0271579310394
ko04138	Autophagy - yeast	3/792	81/7206	0.0310636972964
ko04340	Hedgehog signaling pathway	12/792	58/7206	0.031137889577
ko04014	Ras signaling pathway	42/792	279/7206	0.0314592254503
ko04390	Hippo signaling pathway	30/792	188/7206	0.03296980457
ko05210	Colorectal cancer	16/792	86/7206	0.0349467197521
ko04217	Necroptosis	11/792	178/7206	0.0383386901165
ko04913	Ovarian steroidogenesis	2/792	63/7206	0.0424441298739
ko04640	Hematopoietic cell lineage	2/792	64/7206	0.0426907387481
ko04151	PI3K-Akt signaling pathway	55/792	390/7206	0.0458816350881
ko04974	Protein digestion and absorption	17/792	96/7206	0.0464449335392
ko00603	Glycosphingolipid biosynthesis - globo and isoglobo series	3/792	8/7206	0.048527326891