ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	173/1239	423/7206	9.17169068141e-33
ko04724	Glutamatergic synapse	82/1239	152/7206	2.16382954215e-25
ko05033	Nicotine addiction	43/1239	56/7206	1.33667852531e-22
ko05032	Morphine addiction	63/1239	110/7206	1.33220744715e-21
ko04727	GABAergic synapse	60/1239	110/7206	3.49432780019e-19
ko04713	Circadian entrainment	68/1239	136/7206	7.56862566542e-19
ko04024	cAMP signaling pathway	104/1239	279/7206	2.50494344908e-16
ko04728	Dopaminergic synapse	78/1239	185/7206	5.53366967529e-16
ko04723	Retrograde endocannabinoid signaling	74/1239	175/7206	2.64485605218e-15
ko04020	Calcium signaling pathway	98/1239	265/7206	3.4867828264e-15
ko04725	Cholinergic synapse	68/1239	160/7206	2.73506335943e-14
ko04721	Synaptic vesicle cycle	40/1239	80/7206	1.32163330168e-11
ko04911	Insulin secretion	50/1239	117/7206	6.01001412301e-11
ko04726	Serotonergic synapse	55/1239	137/7206	1.27392155135e-10
ko04921	Oxytocin signaling pathway	74/1239	209/7206	1.46503342077e-10
ko04744	Phototransduction	23/1239	36/7206	5.07608319534e-10
ko04261	Adrenergic signaling in cardiomyocytes	71/1239	205/7206	8.29654830581e-10
ko03010	Ribosome	1/1239	129/7206	9.32704837293e-10
ko03040	Spliceosome	2/1239	145/7206	9.72594822795e-10
ko03013	RNA transport	4/1239	166/7206	2.03441245371e-09
ko04072	Phospholipase D signaling pathway	68/1239	197/7206	2.34597107848e-09
ko05322	Systemic lupus erythematosus	3/1239	151/7206	2.75793248218e-09
ko05031	Amphetamine addiction	38/1239	91/7206	2.6244360241e-08
ko04742	Taste transduction	28/1239	61/7206	1.66061850354e-07
ko04022	cGMP-PKG signaling pathway	68/1239	216/7206	1.85782228831e-07
ko04070	Phosphatidylinositol signaling system	41/1239	112/7206	7.39640826113e-07
ko04925	Aldosterone synthesis and secretion	39/1239	105/7206	7.49461869573e-07
ko05030	Cocaine addiction	30/1239	73/7206	1.15851267552e-06
ko04970	Salivary secretion	35/1239	95/7206	3.52249928125e-06
ko04720	Long-term potentiation	36/1239	99/7206	4.92319868015e-06
ko04110	Cell cycle	7/1239	145/7206	1.03877832376e-05
ko04360	Axon guidance	66/1239	233/7206	1.86623065466e-05
ko04010	MAPK signaling pathway	85/1239	321/7206	1.97960570543e-05
ko04710	Circadian rhythm	19/1239	43/7206	3.17873601435e-05
ko05203	Viral carcinogenesis	24/1239	277/7206	4.49125898055e-05
ko04514	Cell adhesion molecules (CAMs)	41/1239	130/7206	5.13686334907e-05
ko05231	Choline metabolism in cancer	41/1239	134/7206	0.000112124095883
ko04930	Type II diabetes mellitus	21/1239	54/7206	0.000157248835801
ko04923	Regulation of lipolysis in adipocytes	27/1239	77/7206	0.000179395048852
ko04730	Long-term depression	27/1239	78/7206	0.000201393827933
ko04971	Gastric acid secretion	32/1239	98/7206	0.000202755505473
ko04014	Ras signaling pathway	71/1239	279/7206	0.000353907351575
ko04711	Circadian rhythm - fly	8/1239	13/7206	0.000424699555767
ko04972	Pancreatic secretion	34/1239	111/7206	0.000507197356198
ko04612	Antigen processing and presentation	3/1239	77/7206	0.000673912719453
ko00520	Amino sugar and nucleotide sugar metabolism	1/1239	55/7206	0.000871332166549
ko04924	Renin secretion	27/1239	86/7206	0.00128465382136
ko00240	Pyrimidine metabolism	7/1239	110/7206	0.00129028415892
ko05169	Epstein-Barr virus infection	19/1239	206/7206	0.00136757856634
ko05168	Herpes simplex infection	16/1239	182/7206	0.00139199757909
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	25/1239	79/7206	0.00143076210658
ko04964	Proximal tubule bicarbonate reclamation	12/1239	29/7206	0.00185389931203
ko05133	Pertussis	5/1239	87/7206	0.00242589245109
ko03420	Nucleotide excision repair	1/1239	46/7206	0.00280195496871
ko04141	Protein processing in endoplasmic reticulum	17/1239	184/7206	0.0028252305229
ko05014	Amyotrophic lateral sclerosis (ALS)	23/1239	74/7206	0.00292511912547
ko04750	Inflammatory mediator regulation of TRP channels	34/1239	122/7206	0.0033452243242
ko05164	Influenza A	15/1239	167/7206	0.00345394561631
ko04745	Phototransduction - fly	14/1239	38/7206	0.00369997939648
ko04740	Olfactory transduction	24/1239	80/7206	0.00421865494545
ko03022	Basal transcription factors	1/1239	44/7206	0.0042419547154
ko00562	Inositol phosphate metabolism	26/1239	89/7206	0.00436407478888
ko05144	Malaria	1/1239	45/7206	0.00440657860468
ko04371	Apelin signaling pathway	45/1239	177/7206	0.0046551172623
ko04961	Endocrine and other factor-regulated calcium reabsorption	19/1239	59/7206	0.00473199900841
ko05414	Dilated cardiomyopathy	31/1239	112/7206	0.00513266686269
ko04622	RIG-I-like receptor signaling pathway	3/1239	62/7206	0.00621390708138
ko04922	Glucagon signaling pathway	34/1239	128/7206	0.00645774176241
ko04113	Meiosis - yeast	4/1239	70/7206	0.00658378581993
ko04966	Collecting duct acid secretion	10/1239	26/7206	0.00810649121432
ko05130	Pathogenic Escherichia coli infection	5/1239	77/7206	0.00928718617002
ko04270	Vascular smooth muscle contraction	39/1239	154/7206	0.00935126576405
ko04260	Cardiac muscle contraction	27/1239	98/7206	0.009824084682
ko04915	Estrogen signaling pathway	34/1239	131/7206	0.00993632638966
ko04976	Bile secretion	23/1239	80/7206	0.0103714972228
ko04960	Aldosterone-regulated sodium reabsorption	14/1239	41/7206	0.0105603042557
ko04666	Fc gamma R-mediated phagocytosis	32/1239	122/7206	0.0107034568789
ko05230	Central carbon metabolism in cancer	23/1239	81/7206	0.0111418431455
ko04973	Carbohydrate digestion and absorption	14/1239	42/7206	0.0116638101747
ko03018	RNA degradation	6/1239	84/7206	0.0125398895383
ko04540	Gap junction	33/1239	128/7206	0.0127195357443
ko04115	p53 signaling pathway	5/1239	74/7206	0.0128571391994
ko04919	Thyroid hormone signaling pathway	36/1239	143/7206	0.0136030263182
ko03410	Base excision repair	1/1239	38/7206	0.0151609515501
ko05016	Huntington's disease	24/1239	215/7206	0.0167303565796
ko00965	Betalain biosynthesis	3/1239	4/7206	0.0176802831136
ko00280	Valine, leucine and isoleucine degradation	3/1239	54/7206	0.0181188116135
ko04621	NOD-like receptor signaling pathway	16/1239	157/7206	0.0181608555483
ko00480	Glutathione metabolism	3/1239	55/7206	0.0182946577765
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1239	14/7206	0.021960662067
ko05410	Hypertrophic cardiomyopathy (HCM)	26/1239	100/7206	0.0230822602773
ko04610	Complement and coagulation cascades	6/1239	79/7206	0.0232749143272
ko05205	Proteoglycans in cancer	33/1239	271/7206	0.0263995028166
ko02010	ABC transporters	12/1239	39/7206	0.0322586605082
ko04060	Cytokine-cytokine receptor interaction	22/1239	191/7206	0.0326790990268
ko00980	Metabolism of xenobiotics by cytochrome P450	2/1239	40/7206	0.0357982992985
ko05131	Shigellosis	7/1239	82/7206	0.0382510152321
ko05012	Parkinson's disease	17/1239	155/7206	0.0402638096001
ko05134	Legionellosis	6/1239	74/7206	0.0424098308654
ko04213	Longevity regulating pathway - multiple species	22/1239	86/7206	0.0439227259483
ko05110	Vibrio cholerae infection	17/1239	63/7206	0.0443241046158
ko04071	Sphingolipid signaling pathway	38/1239	162/7206	0.0445535473201
ko05416	Viral myocarditis	4/1239	55/7206	0.0486932481273
ko04142	Lysosome	17/1239	151/7206	0.0499288263959