ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	47/458	145/7206	6.24520306381e-22
ko03050	Proteasome	25/458	54/7206	1.91059974212e-16
ko03030	DNA replication	20/458	38/7206	8.92724195776e-15
ko03013	RNA transport	36/458	166/7206	3.66373757793e-11
ko04080	Neuroactive ligand-receptor interaction	2/458	423/7206	3.93465843396e-10
ko03015	mRNA surveillance pathway	24/458	93/7206	1.86805314492e-09
ko05217	Basal cell carcinoma	20/458	68/7206	3.63504795422e-09
ko03008	Ribosome biogenesis in eukaryotes	20/458	79/7206	6.08654422481e-08
ko04110	Cell cycle	28/458	145/7206	8.56247261859e-08
ko00240	Pyrimidine metabolism	22/458	110/7206	1.14235912178e-06
ko03420	Nucleotide excision repair	13/458	46/7206	3.41913940804e-06
ko03430	Mismatch repair	9/458	22/7206	3.69686877386e-06
ko04111	Cell cycle - yeast	18/458	90/7206	1.08269354593e-05
ko04020	Calcium signaling pathway	3/458	265/7206	5.0004448704e-05
ko04932	Non-alcoholic fatty liver disease (NAFLD)	1/458	182/7206	0.000150984905088
ko04390	Hippo signaling pathway	26/458	188/7206	0.000182581999159
ko03410	Base excision repair	9/458	38/7206	0.000485674542648
ko05012	Parkinson's disease	1/458	155/7206	0.000692471853529
ko04621	NOD-like receptor signaling pathway	1/458	157/7206	0.000705948603548
ko03440	Homologous recombination	9/458	41/7206	0.000880334434602
ko04113	Meiosis - yeast	12/458	70/7206	0.0013623367192
ko04723	Retrograde endocannabinoid signaling	2/458	175/7206	0.0014297172281
ko00230	Purine metabolism	24/458	194/7206	0.00147543499669
ko04310	Wnt signaling pathway	23/458	181/7206	0.00160696906297
ko05010	Alzheimer's disease	3/458	202/7206	0.00178209838413
ko04068	FoxO signaling pathway	2/458	167/7206	0.00203907037071
ko04630	Jak-STAT signaling pathway	1/458	132/7206	0.00324085525394
ko05169	Epstein-Barr virus infection	24/458	206/7206	0.00341586260713
ko05224	Breast cancer	21/458	174/7206	0.00407175703068
ko05166	HTLV-I infection	31/458	292/7206	0.00448512377804
ko04066	HIF-1 signaling pathway	1/458	123/7206	0.00463026999404
ko04010	MAPK signaling pathway	9/458	321/7206	0.00478012362585
ko04024	cAMP signaling pathway	7/458	279/7206	0.00538930404519
ko00970	Aminoacyl-tRNA biosynthesis	8/458	44/7206	0.00583842539308
ko04724	Glutamatergic synapse	2/458	152/7206	0.00616182156219
ko04910	Insulin signaling pathway	3/458	172/7206	0.00676218834996
ko04062	Chemokine signaling pathway	4/458	201/7206	0.00743972744033
ko04727	GABAergic synapse	1/458	110/7206	0.00980561973508
ko04972	Pancreatic secretion	1/458	111/7206	0.00982232206335
ko05414	Dilated cardiomyopathy	1/458	112/7206	0.00988354825601
ko04060	Cytokine-cytokine receptor interaction	4/458	191/7206	0.00992088028144
ko04022	cGMP-PKG signaling pathway	5/458	216/7206	0.0100458255128
ko04380	Osteoclast differentiation	2/458	134/7206	0.0120070436794
ko05231	Choline metabolism in cancer	2/458	134/7206	0.0120070436794
ko04931	Insulin resistance	2/458	137/7206	0.0121028628641
ko04725	Cholinergic synapse	3/458	160/7206	0.0131641221953
ko04921	Oxytocin signaling pathway	5/458	209/7206	0.0135779223155
ko03460	Fanconi anemia pathway	8/458	51/7206	0.0142326667371
ko04330	Notch signaling pathway	9/458	62/7206	0.0156421634781
ko04915	Estrogen signaling pathway	2/458	131/7206	0.0171835658585
ko04270	Vascular smooth muscle contraction	3/458	154/7206	0.018302666107
ko04371	Apelin signaling pathway	4/458	177/7206	0.0185385300348
ko04217	Necroptosis	4/458	178/7206	0.0186038404222
ko04261	Adrenergic signaling in cardiomyocytes	5/458	205/7206	0.0187471091042
ko04971	Gastric acid secretion	1/458	98/7206	0.0206383449183
ko05410	Hypertrophic cardiomyopathy (HCM)	1/458	100/7206	0.0209163567677
ko04620	Toll-like receptor signaling pathway	1/458	100/7206	0.0209163567677
ko04014	Ras signaling pathway	9/458	279/7206	0.0241756172565
ko05145	Toxoplasmosis	2/458	126/7206	0.0246316528301
ko05120	Epithelial cell signaling in Helicobacter pylori infection	1/458	92/7206	0.0298801001658
ko04970	Salivary secretion	1/458	95/7206	0.0307788492262
ko04064	NF-kappa B signaling pathway	1/458	96/7206	0.0313185973546
ko05152	Tuberculosis	5/458	187/7206	0.0327532153153
ko04911	Insulin secretion	2/458	117/7206	0.0338013707796
ko00670	One carbon pool by folate	4/458	20/7206	0.0346108604157
ko04668	TNF signaling pathway	2/458	120/7206	0.0348259391653
ko05164	Influenza A	4/458	167/7206	0.0348723184062
ko00514	Other types of O-glycan biosynthesis	5/458	30/7206	0.0387017420588
ko04917	Prolactin signaling pathway	1/458	87/7206	0.0435082782366
ko05133	Pertussis	1/458	87/7206	0.0435082782366
ko04662	B cell receptor signaling pathway	1/458	88/7206	0.0439871537012
ko05032	Morphine addiction	2/458	110/7206	0.0472431076445
ko04070	Phosphatidylinositol signaling system	2/458	112/7206	0.0478890992375
ko04933	AGE-RAGE signaling pathway in diabetic complications	3/458	135/7206	0.0479744605768
ko04713	Circadian entrainment	3/458	136/7206	0.0483313165528
ko04726	Serotonergic synapse	3/458	137/7206	0.0488012021684