ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	157/1013	423/7206	1.11945643501e-34
ko05033	Nicotine addiction	46/1013	56/7206	2.24754817624e-30
ko04724	Glutamatergic synapse	79/1013	152/7206	4.15045517027e-29
ko05032	Morphine addiction	62/1013	110/7206	1.35577702312e-25
ko04727	GABAergic synapse	60/1013	110/7206	8.80062425764e-24
ko04721	Synaptic vesicle cycle	48/1013	80/7206	1.11361612982e-21
ko04728	Dopaminergic synapse	78/1013	185/7206	2.41919834626e-21
ko04713	Circadian entrainment	63/1013	136/7206	5.39854380437e-20
ko04723	Retrograde endocannabinoid signaling	73/1013	175/7206	1.03517251744e-19
ko04725	Cholinergic synapse	65/1013	160/7206	5.78819051046e-17
ko04024	cAMP signaling pathway	91/1013	279/7206	8.15146856691e-16
ko04744	Phototransduction	26/1013	36/7206	3.26295586283e-15
ko04726	Serotonergic synapse	52/1013	137/7206	2.00797874151e-12
ko04742	Taste transduction	30/1013	61/7206	5.35554107087e-11
ko04911	Insulin secretion	44/1013	117/7206	1.48258977135e-10
ko04921	Oxytocin signaling pathway	63/1013	209/7206	9.90984193951e-10
ko04720	Long-term potentiation	38/1013	99/7206	1.36584329599e-09
ko05031	Amphetamine addiction	36/1013	91/7206	1.40803067422e-09
ko04020	Calcium signaling pathway	74/1013	265/7206	2.18050502574e-09
ko04261	Adrenergic signaling in cardiomyocytes	60/1013	205/7206	9.32816289456e-09
ko04966	Collecting duct acid secretion	16/1013	26/7206	2.76231556117e-08
ko05203	Viral carcinogenesis	11/1013	277/7206	2.86181652886e-08
ko04060	Cytokine-cytokine receptor interaction	5/1013	191/7206	1.20368123545e-07
ko03040	Spliceosome	2/1013	145/7206	1.65101680509e-07
ko05030	Cocaine addiction	27/1013	73/7206	8.02107862253e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	27/1013	74/7206	1.0965474199e-06
ko04970	Salivary secretion	32/1013	95/7206	1.41447853221e-06
ko04360	Axon guidance	60/1013	233/7206	1.84145626512e-06
ko03013	RNA transport	6/1013	166/7206	1.25673095144e-05
ko04120	Ubiquitin mediated proteolysis	4/1013	138/7206	1.77313354295e-05
ko05168	Herpes simplex infection	8/1013	182/7206	3.12824735217e-05
ko04514	Cell adhesion molecules (CAMs)	36/1013	130/7206	3.54126759902e-05
ko04925	Aldosterone synthesis and secretion	31/1013	105/7206	4.66814485588e-05
ko04022	cGMP-PKG signaling pathway	52/1013	216/7206	5.99242926176e-05
ko05322	Systemic lupus erythematosus	6/1013	151/7206	7.32930695907e-05
ko04141	Protein processing in endoplasmic reticulum	9/1013	184/7206	8.91912095177e-05
ko04010	MAPK signaling pathway	70/1013	321/7206	0.000104962838214
ko04730	Long-term depression	24/1013	78/7206	0.000115602271867
ko03008	Ribosome biogenesis in eukaryotes	1/1013	79/7206	0.000130048330719
ko04070	Phosphatidylinositol signaling system	31/1013	112/7206	0.000155484125512
ko04971	Gastric acid secretion	28/1013	98/7206	0.000175732566738
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/1013	14/7206	0.000202676807003
ko04924	Renin secretion	25/1013	86/7206	0.00024660836889
ko05110	Vibrio cholerae infection	20/1013	63/7206	0.000319474325918
ko05205	Proteoglycans in cancer	19/1013	271/7206	0.000335878335694
ko05164	Influenza A	9/1013	167/7206	0.000433405267649
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/1013	79/7206	0.000455435449817
ko05169	Epstein-Barr virus infection	13/1013	206/7206	0.000513798684821
ko04915	Estrogen signaling pathway	33/1013	131/7206	0.000554766607986
ko04064	NF-kappa B signaling pathway	3/1013	96/7206	0.000570103096931
ko05162	Measles	5/1013	120/7206	0.000768957110805
ko04972	Pancreatic secretion	29/1013	111/7206	0.000773623321247
ko04260	Cardiac muscle contraction	26/1013	98/7206	0.0010484068016
ko04745	Phototransduction - fly	13/1013	38/7206	0.00138463410862
ko04621	NOD-like receptor signaling pathway	9/1013	157/7206	0.00153298757042
ko04110	Cell cycle	8/1013	145/7206	0.00153548883868
ko04740	Olfactory transduction	22/1013	80/7206	0.00166756773453
ko04146	Peroxisome	3/1013	89/7206	0.00176971819238
ko04540	Gap junction	31/1013	128/7206	0.00185650417975
ko04014	Ras signaling pathway	58/1013	279/7206	0.00198612878273
ko00240	Pyrimidine metabolism	5/1013	110/7206	0.00207313034411
ko05120	Epithelial cell signaling in Helicobacter pylori infection	24/1013	92/7206	0.00213865517908
ko03018	RNA degradation	3/1013	84/7206	0.00245406335029
ko05321	Inflammatory bowel disease (IBD)	1/1013	56/7206	0.00330761512261
ko04964	Proximal tubule bicarbonate reclamation	10/1013	29/7206	0.00456574961903
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/1013	182/7206	0.00477105126615
ko00480	Glutathione metabolism	1/1013	55/7206	0.00517284545956
ko05161	Hepatitis B	12/1013	173/7206	0.0052880784179
ko04640	Hematopoietic cell lineage	2/1013	64/7206	0.00631602527958
ko05140	Leishmaniasis	3/1013	75/7206	0.00714394417357
ko00590	Arachidonic acid metabolism	1/1013	52/7206	0.00766092844084
ko04626	Plant-pathogen interaction	7/1013	18/7206	0.00821968217277
ko05414	Dilated cardiomyopathy	26/1013	112/7206	0.00856244085753
ko04072	Phospholipase D signaling pathway	41/1013	197/7206	0.00896112128021
ko05145	Toxoplasmosis	8/1013	126/7206	0.00929261058607
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	6/1013	15/7206	0.012256862363
ko04510	Focal adhesion	21/1013	240/7206	0.0139269247265
ko04630	Jak-STAT signaling pathway	9/1013	132/7206	0.0154956051186
ko03022	Basal transcription factors	1/1013	44/7206	0.0161951622226
ko05144	Malaria	1/1013	45/7206	0.0162767618461
ko00071	Fatty acid degradation	1/1013	45/7206	0.0162767618461
ko03420	Nucleotide excision repair	1/1013	46/7206	0.0167489415285
ko00515	Mannose type O-glycan biosynthesis	8/1013	25/7206	0.0175506721799
ko05222	Small cell lung cancer	5/1013	89/7206	0.0200858956248
ko01200	Carbon metabolism	9/1013	128/7206	0.0201077260316
ko04612	Antigen processing and presentation	4/1013	77/7206	0.0203439619651
ko04391	Hippo signaling pathway - fly	21/1013	90/7206	0.0205709774753
ko04976	Bile secretion	19/1013	80/7206	0.0217505156423
ko05034	Alcoholism	46/1013	238/7206	0.0223992696863
ko04750	Inflammatory mediator regulation of TRP channels	26/1013	122/7206	0.0251263482476
ko04115	p53 signaling pathway	4/1013	74/7206	0.0280888786334
ko00280	Valine, leucine and isoleucine degradation	2/1013	54/7206	0.0280898223375
ko05206	MicroRNAs in cancer	15/1013	177/7206	0.0283570158775
ko00600	Sphingolipid metabolism	3/1013	63/7206	0.0283994802205
ko01524	Platinum drug resistance	4/1013	76/7206	0.0290126575044
ko04350	TGF-beta signaling pathway	7/1013	103/7206	0.0314420402188
ko00630	Glyoxylate and dicarboxylate metabolism	1/1013	38/7206	0.0354433621671
ko00980	Metabolism of xenobiotics by cytochrome P450	1/1013	40/7206	0.0364107390281
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/1013	59/7206	0.038464388011
ko05166	HTLV-I infection	29/1013	292/7206	0.0388704526498
ko04214	Apoptosis - fly	4/1013	72/7206	0.039024980712
ko00380	Tryptophan metabolism	2/1013	50/7206	0.0393369551744
ko04071	Sphingolipid signaling pathway	32/1013	162/7206	0.0394806860092
ko00310	Lysine degradation	4/1013	73/7206	0.0398860711521
ko00330	Arginine and proline metabolism	3/1013	61/7206	0.0400182057773
ko04140	Autophagy - animal	14/1013	164/7206	0.0402653739096
ko05146	Amoebiasis	7/1013	99/7206	0.0414925514248
ko05231	Choline metabolism in cancer	27/1013	134/7206	0.0448333005454
ko04930	Type II diabetes mellitus	13/1013	54/7206	0.0465075496856
ko04912	GnRH signaling pathway	25/1013	122/7206	0.0477927487537