ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	74/442	423/7206	2.6109257046e-17
ko05033	Nicotine addiction	22/442	56/7206	3.92836680615e-13
ko04724	Glutamatergic synapse	34/442	152/7206	1.99696125662e-11
ko04727	GABAergic synapse	28/442	110/7206	4.94691659974e-11
ko04728	Dopaminergic synapse	37/442	185/7206	8.33398146712e-11
ko04740	Olfactory transduction	22/442	80/7206	1.24759656308e-09
ko05032	Morphine addiction	24/442	110/7206	3.31299614866e-08
ko04974	Protein digestion and absorption	21/442	96/7206	2.3152463111e-07
ko04742	Taste transduction	16/442	61/7206	4.78283266758e-07
ko04723	Retrograde endocannabinoid signaling	29/442	175/7206	7.10553053344e-07
ko04713	Circadian entrainment	24/442	136/7206	2.09674732857e-06
ko04744	Phototransduction	11/442	36/7206	6.0494527269e-06
ko05030	Cocaine addiction	16/442	73/7206	6.27008690907e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	16/442	74/7206	7.55665326662e-06
ko04726	Serotonergic synapse	23/442	137/7206	8.18347719562e-06
ko04725	Cholinergic synapse	25/442	160/7206	1.22926377601e-05
ko04721	Synaptic vesicle cycle	15/442	80/7206	8.51692644406e-05
ko04060	Cytokine-cytokine receptor interaction	1/442	191/7206	0.000160866146143
ko04964	Proximal tubule bicarbonate reclamation	8/442	29/7206	0.000256673328984
ko05161	Hepatitis B	1/442	173/7206	0.000323441677236
ko05031	Amphetamine addiction	15/442	91/7206	0.000377652026695
ko05164	Influenza A	1/442	167/7206	0.000475996739759
ko04024	cAMP signaling pathway	32/442	279/7206	0.000508185313768
ko04140	Autophagy - animal	1/442	164/7206	0.000729628431513
ko04512	ECM-receptor interaction	13/442	79/7206	0.000930200817558
ko04976	Bile secretion	13/442	80/7206	0.00105023160285
ko04151	PI3K-Akt signaling pathway	40/442	390/7206	0.00106357041182
ko04514	Cell adhesion molecules (CAMs)	18/442	130/7206	0.00115934459524
ko05168	Herpes simplex infection	2/442	182/7206	0.00144918932598
ko05166	HTLV-I infection	6/442	292/7206	0.00161859691093
ko03013	RNA transport	2/442	166/7206	0.00294142307295
ko05203	Viral carcinogenesis	6/442	277/7206	0.00297458968186
ko04611	Platelet activation	2/442	163/7206	0.00428669233108
ko05016	Huntington's disease	4/442	215/7206	0.00541916692432
ko04911	Insulin secretion	15/442	117/7206	0.00560408219466
ko04217	Necroptosis	3/442	178/7206	0.00680264617259
ko04211	Longevity regulating pathway	1/442	123/7206	0.00687141054914
ko04066	HIF-1 signaling pathway	1/442	123/7206	0.00687141054914
ko04932	Non-alcoholic fatty liver disease (NAFLD)	3/442	182/7206	0.00694970180395
ko05034	Alcoholism	25/442	238/7206	0.00826587115788
ko05322	Systemic lupus erythematosus	2/442	151/7206	0.00883143438093
ko04961	Endocrine and other factor-regulated calcium reabsorption	9/442	59/7206	0.00918645714928
ko04978	Mineral absorption	7/442	40/7206	0.00994703076653
ko04110	Cell cycle	2/442	145/7206	0.0126459004178
ko00830	Retinol metabolism	7/442	42/7206	0.0129568640032
ko00350	Tyrosine metabolism	6/442	33/7206	0.0138436466545
ko05215	Prostate cancer	1/442	111/7206	0.0146739308495
ko04970	Salivary secretion	12/442	95/7206	0.0152215554978
ko04120	Ubiquitin mediated proteolysis	2/442	138/7206	0.0177651183754
ko05169	Epstein-Barr virus infection	5/442	206/7206	0.0182799023655
ko04150	mTOR signaling pathway	4/442	184/7206	0.0186552675608
ko04141	Protein processing in endoplasmic reticulum	4/442	184/7206	0.0186552675608
ko05152	Tuberculosis	4/442	187/7206	0.0190468176741
ko00190	Oxidative phosphorylation	2/442	127/7206	0.0240738745735
ko01200	Carbon metabolism	2/442	128/7206	0.0241719706592
ko04630	Jak-STAT signaling pathway	2/442	132/7206	0.0252936421421
ko04142	Lysosome	3/442	151/7206	0.0253107657324
ko00910	Nitrogen metabolism	4/442	19/7206	0.0259285861506
ko05205	Proteoglycans in cancer	8/442	271/7206	0.027004489233
ko00564	Glycerophospholipid metabolism	1/442	99/7206	0.0312138642955
ko01522	Endocrine resistance	2/442	124/7206	0.0348251378954
ko04261	Adrenergic signaling in cardiomyocytes	20/442	205/7206	0.0372248320742
ko04146	Peroxisome	1/442	89/7206	0.0433675851737
ko04068	FoxO signaling pathway	4/442	167/7206	0.047588391314
ko04931	Insulin resistance	3/442	137/7206	0.0477651683964