ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	157/986	423/7206	3.58812460129e-36
ko04724	Glutamatergic synapse	72/986	152/7206	3.68651275051e-24
ko05033	Nicotine addiction	39/986	56/7206	9.94868789852e-22
ko05032	Morphine addiction	54/986	110/7206	2.79473583768e-19
ko04713	Circadian entrainment	61/986	136/7206	4.01257235818e-19
ko04020	Calcium signaling pathway	90/986	265/7206	1.35770713344e-17
ko04723	Retrograde endocannabinoid signaling	63/986	175/7206	4.18757332622e-14
ko04727	GABAergic synapse	47/986	110/7206	5.06043073605e-14
ko04725	Cholinergic synapse	59/986	160/7206	8.18289233605e-14
ko04921	Oxytocin signaling pathway	69/986	209/7206	3.61504610256e-13
ko04024	cAMP signaling pathway	84/986	279/7206	4.10270557525e-13
ko04728	Dopaminergic synapse	62/986	185/7206	3.67659849306e-12
ko04911	Insulin secretion	44/986	117/7206	5.98998380832e-11
ko04726	Serotonergic synapse	48/986	137/7206	1.45377441526e-10
ko04022	cGMP-PKG signaling pathway	65/986	216/7206	2.37748793026e-10
ko04360	Axon guidance	66/986	233/7206	2.50758916436e-09
ko04721	Synaptic vesicle cycle	31/986	80/7206	1.83337999992e-08
ko04742	Taste transduction	25/986	61/7206	1.2157579994e-07
ko04970	Salivary secretion	33/986	95/7206	1.42325215582e-07
ko04261	Adrenergic signaling in cardiomyocytes	56/986	205/7206	1.54020215722e-07
ko03010	Ribosome	1/986	129/7206	1.82544888719e-07
ko03040	Spliceosome	2/986	145/7206	2.48884914658e-07
ko05031	Amphetamine addiction	31/986	91/7206	5.57211277051e-07
ko05322	Systemic lupus erythematosus	3/986	151/7206	9.07944593178e-07
ko04730	Long-term depression	27/986	78/7206	2.09758827665e-06
ko03013	RNA transport	5/986	166/7206	5.38972274694e-06
ko04010	MAPK signaling pathway	72/986	321/7206	1.30359732847e-05
ko04720	Long-term potentiation	30/986	99/7206	1.98836441173e-05
ko04710	Circadian rhythm	17/986	43/7206	2.27928831757e-05
ko04514	Cell adhesion molecules (CAMs)	36/986	130/7206	2.42039911738e-05
ko04014	Ras signaling pathway	63/986	279/7206	3.72871142571e-05
ko04540	Gap junction	35/986	128/7206	3.91119737444e-05
ko04925	Aldosterone synthesis and secretion	30/986	105/7206	7.22120261819e-05
ko05164	Influenza A	7/986	167/7206	8.40720015133e-05
ko05030	Cocaine addiction	23/986	73/7206	8.61627972735e-05
ko04971	Gastric acid secretion	28/986	98/7206	8.77051481847e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	23/986	74/7206	0.000100872699961
ko04371	Apelin signaling pathway	43/986	177/7206	0.000134330655672
ko05203	Viral carcinogenesis	18/986	277/7206	0.000163196757616
ko04072	Phospholipase D signaling pathway	46/986	197/7206	0.000199652050095
ko04270	Vascular smooth muscle contraction	38/986	154/7206	0.000200860719835
ko04120	Ubiquitin mediated proteolysis	6/986	138/7206	0.000414155339672
ko05414	Dilated cardiomyopathy	29/986	112/7206	0.00045870028066
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/986	79/7206	0.000779217673496
ko04961	Endocrine and other factor-regulated calcium reabsorption	18/986	59/7206	0.000783628894682
ko04972	Pancreatic secretion	28/986	111/7206	0.00112777233362
ko05168	Herpes simplex infection	11/986	182/7206	0.00140179153974
ko05410	Hypertrophic cardiomyopathy (HCM)	25/986	100/7206	0.00194458555881
ko04015	Rap1 signaling pathway	56/986	278/7206	0.00236080675355
ko04214	Apoptosis - fly	2/986	72/7206	0.00304198721643
ko04260	Cardiac muscle contraction	24/986	98/7206	0.00428008013877
ko04711	Circadian rhythm - fly	6/986	13/7206	0.00469977421153
ko04750	Inflammatory mediator regulation of TRP channels	28/986	122/7206	0.00486112243705
ko04070	Phosphatidylinositol signaling system	26/986	112/7206	0.0052710537101
ko04141	Protein processing in endoplasmic reticulum	13/986	184/7206	0.00632161983764
ko04612	Antigen processing and presentation	3/986	77/7206	0.00725985564662
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/986	14/7206	0.00728415390601
ko04011	MAPK signaling pathway - yeast	1/986	53/7206	0.00765869299253
ko00240	Pyrimidine metabolism	6/986	110/7206	0.0076588109284
ko04146	Peroxisome	4/986	89/7206	0.0076996701063
ko04930	Type II diabetes mellitus	15/986	54/7206	0.0080252874586
ko04142	Lysosome	10/986	151/7206	0.00816763438123
ko04960	Aldosterone-regulated sodium reabsorption	12/986	41/7206	0.00939094629615
ko05133	Pertussis	4/986	87/7206	0.0109538397546
ko05204	Chemical carcinogenesis	1/986	48/7206	0.0111012795278
ko04740	Olfactory transduction	19/986	80/7206	0.0132448988428
ko01212	Fatty acid metabolism	2/986	60/7206	0.0134088319755
ko04110	Cell cycle	10/986	145/7206	0.0141267414434
ko04745	Phototransduction - fly	11/986	38/7206	0.014255669924
ko00071	Fatty acid degradation	1/986	45/7206	0.0164407814357
ko04924	Renin secretion	20/986	86/7206	0.0164410018475
ko03420	Nucleotide excision repair	1/986	46/7206	0.0164459581595
ko04923	Regulation of lipolysis in adipocytes	18/986	77/7206	0.0186465206783
ko04071	Sphingolipid signaling pathway	33/986	162/7206	0.0199353261082
ko03320	PPAR signaling pathway	3/986	69/7206	0.0206716880098
ko05162	Measles	8/986	120/7206	0.0220963130793
ko05169	Epstein-Barr virus infection	17/986	206/7206	0.0229802413902
ko03022	Basal transcription factors	1/986	44/7206	0.0248682876248
ko04621	NOD-like receptor signaling pathway	12/986	157/7206	0.0250891986192
ko04626	Plant-pathogen interaction	6/986	18/7206	0.0278219721264
ko04217	Necroptosis	15/986	178/7206	0.0360127943304
ko00140	Steroid hormone biosynthesis	1/986	41/7206	0.0366918577834
ko04922	Glucagon signaling pathway	26/986	128/7206	0.0367073617407
ko00310	Lysine degradation	4/986	73/7206	0.0390203409572
ko04630	Jak-STAT signaling pathway	10/986	132/7206	0.0400815083067
ko04622	RIG-I-like receptor signaling pathway	3/986	62/7206	0.04016730518
ko00590	Arachidonic acid metabolism	2/986	52/7206	0.0401801856408